Patents Examined by P. Kulkosqy
  • Conjugates of superoxide dismutage coupled to high molecular weight polyalkylene glycols
    Patent number: 5468478
    Abstract: A biologically persistent, water-soluble, substantially non-immunogenic, substantially non-antigenic conjugate of superoxide dismutase is prepared by coupling one to five strands of a polyalkylene glycol which is polyethylene glycol or polyethylene-polypropylene glycol copolymer, wherein said polyalkylene glycol has an average molecular weight of about 35,000-1,000,000.
    Type: Grant
    Filed: October 18, 1993
    Date of Patent: November 21, 1995
    Assignee: Oxis International, Inc.
    Inventors: Mark Saifer, Ralph Somack, L. David Williams