Patents Examined by Padmavathi V. Baskar
  • Polypeptides and polynucleotides BASB040 from neisseria meningitidis and vaccine comprising said polypeptides and polynucleotides
    Patent number: 6770284
    Abstract: The invention provides BASB040 polypeptides and polynticleotides from Neisseria meningitidis encoding BASB040 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
    Type: Grant
    Filed: September 21, 2001
    Date of Patent: August 3, 2004
    Assignee: GlaxoSmithKline Biological S.A.
    Inventor: Jean-Louis Ruelle
  • Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
    Patent number: 6638517
    Abstract: Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: October 28, 2003
    Assignee: Corixa Corporation
    Inventors: Steven G. Reed, Antonio Campos-Neto, John R. Webb, Davin C. Dillon, Yasir A. W. Skeiky, Ajay Bhatia, Rhea N. Coler, Peter Probst, Mark Brannon
  • Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
    Patent number: 6613337
    Abstract: Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
    Type: Grant
    Filed: August 14, 2000
    Date of Patent: September 2, 2003
    Assignee: Corixa Corporation
    Inventors: Steven G. Reed, Antonio Campos-Neto, John R. Webb, Davin C. Dillon, Yasir A. W. Skeiky, Ajay Bhatia, Rhea Coler, Peter Probst
  • Chimeric gene formed of the DNA sequences that encode the antigenic determinants of four proteins of L. infantum, useful of serologic diagnosis of canine leishmaniosis and protein obtained
    Patent number: 6525186
    Abstract: A chimeric polypeptide encoded by a chimeric gene formed by DNA sequences that encode four antigenic determinants of L. infantum is disclosed. These antigenic determinants are obtained from rLiP2a, rLiP2b, rLiH2A and rLiPO. The protein obtained, has a molecular mass of 38 KD with an isoelectric point of 7.37. This chimeric polypeptide is useful for diagnosing, preventing and/or treating leishmaniosis in animals or humans.
    Type: Grant
    Filed: February 21, 2001
    Date of Patent: February 25, 2003
    Assignee: C.B.F. Leti S.A.
    Inventors: Carlos Alonso Bebate, Jose Maria Requena Rolania, Manuel Soto Alvarez
  • Cloning and characterization of bves, a novel gene expressed in heart and uses thereof
    Patent number: 6503540
    Abstract: The present invention is directed to cloning and characterization of bves (blood vessel/epicardial substance), a cDNA expressed in developing and adult heart and skeletal muscle cells in chick, mouse and human. Also provided are applications of Bves as a marker for cardiovascular or skeletal muscle diseases.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: January 7, 2003
    Inventors: David E. Reese, David M. Bader