Abstract: Assessing decongestive therapy delivered to a heart failure patient involves use of an implantable sensor configured to sense a physiologic parameter indicative of the patient's diuresis status and a processor coupled to the implantable sensor. The sensor may comprise a thoracic fluid sensor, a heart sounds sensor, a cardiac chamber or arterial pressure sensor, a respiration sensor, or a blood chemistry sensor, for example. The processor is configured to determine if a target level of patient diuresis has been achieved based on a relationship between the sensed physiologic parameter and a threshold developed for the patient, and to produce an output in response to determining that the target level of patient diuresis has been achieved. The processor may be disposed in an implantable housing, in a patient-external housing, or in a network server system.

Abstract: Methods and devices to deliver a tactile speech analog to a person's skin providing a silent, invisible, hands-free, eyes-free, and ears-free way to receive and directly comprehend electronic communications. Embodiments include an alternative to hearing aids that will enable people with hearing loss to better understand speech. A device, worn like watch or bracelet, supplements a person's remaining hearing to help identify and disambiguate those sounds he or she can not hear properly. Embodiments for hearing aids and hearing prosthetics are also described.

Abstract: An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic never through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

Abstract: An intrauterine device includes an articulating array. The intrauterine device can be operated by articulating the articulating array into an installed position or geometry within the uterus of a patient. Further, the articulating array can be constructed to include an insertion geometry have a smaller cross section than an installation geometry. The articulating array can also be constructed to be housed within a sheath in the intrauterine device. Once the sheath has been inserted into a patient, for example through the patient's cervix, the articulating array can be deployed in its insertion geometry and then articulated into an installed position. The articulating array can include a plurality of expansion chambers. The expansion chambers can be constructed and arranged to take on the installed geometry when expanded. In one embodiment, the purpose of the articulating array is to position a conductive array within the patient's uterus enabling ablation of the uterine lining.

Abstract: A temporary implantable medical device lead includes a connector, a helically coiled conductor and a first mechanical element. The connector is configured to connect the lead to an external control module. The helically coiled conductor has a proximal end mechanically and electrically connected to the connector. The conductor includes a plurality of filars mechanically and electrically connected to the connector. The first mechanical element includes a metal tube having a plurality of longitudinally spaced grooves formed along an exterior of the tube. The plurality of longitudinally spaced grooves receives at least some of the plurality of filars. The at least some of the plurality of filars electrically connected to the first mechanical element such that the first mechanical element is configured as an electrode to deliver electrical stimulation to portions or systems of a body from the external control module.

Abstract: Systems and methods are provided for controlling an entity in response to activity in a peripheral nerve comprising a plurality of fascicles. A multicontact electrode assembly is configured to record activity from the peripheral nerve. A processing component includes a sensor mapping component configured to quantify activity associated with a proper subset of the plurality of fascicles, an evaluation component configured to determine an adjustment of the status of the controlled entity from the quantified activity of the proper subset of the plurality of fascicles, and a controller configured to provide a control signal, representing the adjustment of the status of the controlled entity, to the controlled entity.

Abstract: Devices, systems and methods for reducing migration of leads, catheters and similar devices are provided. In particular, devices, systems and methods are provided for creating a slack anchor which assists in maintaining the lead or catheter in a desired position. In some embodiments, the slack anchor is created within the epidural space. When targeting nerve anatomy within the spinal column or in the vicinity of the epidural space, anchoring within the epidural space allows the associated lead or catheter to be anchored as close to the target therapy site as desired or possible. By anchoring close to the target therapy site, the risk of movement or migration is significantly reduced or eliminated.

Abstract: Thermal management solutions for wireless power transfer systems are provided, which may include any number of features. In one embodiment, an implantable wireless power receiver includes at least one thermal layer disposed on an interior surface of the receiver configured to conduct heat from a central portion of the receiver towards edges of the receiver. The thermal layer can comprise, for example, a copper layer or a ceramic layer embedded in an acrylic polymer matrix. In some embodiments, a plurality of thermal channels can be formed within the receiver to transport heat from central regions of the receiver towards edges of the receiver via free convection. In yet another embodiment, a fluid pipe can be connected to the receiver and be configured to carry heat from the receiver to a location remote from the receiver. Methods of use are also provided.

Abstract: A lead system and method of use for treating breathing disorders by the transvenous stimulation of the phrenic nerve. The lead is implanted in a vein near one portion of the phrenic nerve.

Abstract: A method is provided for non-contact cardiac assessment of a subject. Images of the subject are captured from at least two synchronized independent imaging devices spaced equidistant from the subject and positioned such that each imaging device captures an image of the subject different from other imaging devices. Spectral components of the captured images are extracted. The extracted spectral components are analyzed. A signal corresponding to cardiac information is identified in the extracted spectral components. The identified signal corresponding to the cardiac information is extracted from the extracted spectral components.

Abstract: RF/MRI compatible leads include at least one conductor that turns back on itself at least twice in a lengthwise direction, and can turn back on itself at least twice at multiple locations along its length. The at least one electrical lead can be configured so that the lead heats local tissue less than about 10 degrees Celsius (typically about 5 degrees Celsius or less) or does not heat local tissue when a patient is exposed to target RF frequencies at a peak input SAR of at least about 4 W/kg and/or a whole body average SAR of at least about 2 W/kg. Related devices and methods of fabricating leads are also described.

Abstract: Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers.

Abstract: A system and method to select segments of cardiac signals. Each of a plurality of segments in a first signal is correlated at a plurality of offsets to determine a highest correlation coefficient for each of the plurality of segments in the first signal. Each of a plurality of segments in a second signal is correlated at the plurality of offsets to determine a highest correlation coefficient for each of the plurality of segments in the second signal. A plurality of composite correlation coefficients is generated using highest correlation coefficients for segments of the first signal and segments of the second signal. The segments of the first and second signals are approximately contemporaneous. A set of segments including a segment from the first signal and a segment from the second signal is selected. The set is associated with a highest composite correlation coefficient from the plurality of composite correlation coefficients.

Abstract: A method for knitting a garment having a tubular form, including knitting at least one conductive textile electrode on a machine having N participating feeders and M needles. The method includes the steps of continuously knitting the tubular form with one or more flexible non-conductive yarns, and knitting the electrode integrally within the tubular form, using a conductive yarn, in addition to the non-conductive yarns. The conductive yarn is knitted in a float-loop form by knitting a stitch and skipping over y needles, as follows: repeatably knitting a line segment Lk, using feeder Fi and starting at needle D1; and knitting line segment Lk+1, using the next feeder and start stitching the first float-loop at needle D1+s where 0<s<y. The tubular form has a preconfigured 10 knitting density, wherein the electrode has a knitting density that is higher than the preconfigured knitting density of the tubular form.

Abstract: An exemplary system includes a processing facility and a control facility. The processing facility is configured to 1) divide an audio signal presented to a cochlear implant patient into a plurality of analysis channels each containing a frequency domain signal, and 2) maintain data representative of a crossover frequency. The control facility is configured to 1) direct a cochlear implant to apply electrical stimulation representative of each frequency domain signal included in a plurality of low frequency analysis channels located below the crossover frequency in accordance with a low frequency stimulation strategy that includes a degree of focusing, and 2) direct the cochlear implant to apply electrical stimulation representative of each frequency domain signal included in a plurality of high frequency analysis channels located above the crossover frequency in accordance with a high frequency stimulation strategy that includes a lesser degree of focusing than the low frequency stimulation strategy.

Abstract: A method including measuring cardiac beats in signals at one or more electrodes on a catheter in response to electrical activity in the heart cavity and collecting a plurality of additional data signals related to the cardiac beats, computing criteria that is used to characterize beat morphology of a cardiac beat in the plurality of additional data signals, the criteria based on a comparison of the plurality of additional data signals and a beat template, selecting a subset of less than all of the cardiac beats in the signals measured by the one or more electrodes by determining, based on the criteria, whether to select the cardiac beat and include beat data for the cardiac beat, and determining physiological information based on the selected subset of less than all of the cardiac beats in the signals measured by the one or more electrodes.

Abstract: Aspects are generally directed to techniques for determining weights for stimulation channels of a stimulating hearing prosthesis. The determined weights are used to provide stimulation to a recipient of the stimulating hearing prosthesis.

Abstract: An active implantable medical device includes a VNS pulse bursts generator for stimulation of the vagus nerve according to several selectable configurations. The device may further include a sensor of the current activity level of the patient. The generator is controlled on the activity signal via a classifier determining the of class the current level of activity among a plurality of classes of activity. A controller selects a configuration of VNS therapy depending on the class of activity thus determined. Limits of the activity classes are dynamically changeable by a calibration module that conducts a historical analysis of the successive current activity levels over a predetermined analysis period. The calibration module can prepare a histogram of the historical analysis, and can define the limits of the activity classes depending on the outcome of the historical analysis and the histogram.

Abstract: A blood flow index calculating method includes: obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body; extracting an area of the first site of the living body and an area of the second site of the living body, by a processor; detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body, by the processor; first calculating a delay amount from the pulse wave pattern of the first site and the pulse wave pattern of the second site, by the processor; and second calculating an index related to blood flow by using the delay amount, by the processor.

Abstract: A cutting element for a cutting head for a device for cutting hair is disclosed. A laser beam is directed across a cutting zone, in the cutting head, substantially parallel to a user's skin. The laser beam has an effective cutting region in which the laser beam is of a sufficient intensity to cut hair entering said region. The cutting element has a guard adjacent to the cutting zone to contact a user's skin and space the laser beam there from. The guard has a non-planar shape in a direction extending across the cutting zone so that it substantially follows the contours of an edge of the effective cutting region of the laser beam to reduce any variation in the distance between the edge of the effective cutting region and the user's skin across the length of the cutting zone.