Patents Examined by Patricia Leith
  • Patent number: 8951584
    Abstract: A fish feed comprises carvacrol and/or salvia extract (provided that where the fish feed comprises carvacrol and not salvia extract the lipid content of the fish feed is at least 15 wt %). The salvia extract may be selected from extract of Salvia officinalis and extract of Salvia lavandulifolia. The carvacrol may be synthetic or may be extracted from Origanum vulgare.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: February 10, 2015
    Assignee: Trouw International B.V.
    Inventors: Wolfgang Koppe, Alex Obach, Ramon Fontanillas
  • Patent number: 8937043
    Abstract: The invention concerns a method for obtaining a highly enriched TGF-beta protein fraction in activated form, from a liquid solution rich in proteins said to be soluble in the aqueous phase of milk and/or of whey, said method comprising the following steps; a) adjusting soluble proteins purified at a concentration between 5 and 30 g/liter of solution; b) precipitating part of the whey proteins by acidic treatment of the solution thus obtained to a pH ranging between 4 and 5.5 and at a temperature ranging between 55° C. and 68° C.; c) carrying out a microfiltration of the treated solution by diafiltration, so as to obtain respectively a microfiltration retentate and a microfiltrate; d) recuperating the microfiltration retentate containing the protein fraction highly enriched in TGF-beta; e) drying the microfiltration retentate which has been subjected to diafiltration to obtain a powder highly enriched in TGF-beta.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: January 20, 2015
    Assignee: Piere Jouan Biotechnologies S.A.
    Inventors: Jean-Louis Maubois, Jacques Fauquant, Pierre Jouan, Michel Bourtourault
  • Patent number: 8927243
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: January 6, 2015
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Patent number: 8916698
    Abstract: The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 23, 2014
    Assignee: University of South Florida
    Inventor: Matt Ewert
  • Patent number: 8911985
    Abstract: The present invention relates to a composition comprising a stable aqueous dispersion of polymer particles, an oxidoreductase, and a cofactor for the oxidoreductase and a method for its preparation. The invention is useful for converting certain classes of VOCs to non-VOCs.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: December 16, 2014
    Assignee: Rohm and Haas Company
    Inventors: David L. Frattarelli, Kathleen Rising Manna, James Charles Bohling, Selvanathan Arumugam
  • Patent number: 8906881
    Abstract: Chitosan-based nail formulations are useful to treat nail inflammatory diseases like psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may have a content in chitosan, chitosan derivative or a salt thereof from 0.1 to 25 wt. % with respect to the total weight of the formulation.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: December 9, 2014
    Assignee: Polichem SA
    Inventor: Federico Mailland
  • Patent number: 8906679
    Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: December 9, 2014
    Assignee: Taipei Veterans General Hospital
    Inventors: Shih-Hwa Chiou, Cherng-Kang Perng, Han-Tzo Lin, Yi-Ping Yang
  • Patent number: 8900645
    Abstract: The present invention relates to an extract obtained by extracting useful components containing equol from an equol-containing fermented soybean hypocotyl, and to a method for producing the same. The present invention makes it possible to efficiently obtain useful components containing equol from the fermented soybean hypocotyl by subjecting an equol-containing fermented soybean hypocotyl to extraction using an ethanol aqueous solution as an extractant. The present invention reduces the content of saponin, which causes an unpleasant taste, by sequentially subjecting the equol-containing fermented soybean hypocotyl to extraction using an ethanol aqueous solution and ethanol, while efficiently extracting equol and glycitein.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: December 2, 2014
    Assignee: Otsuka Pharmaceuticals Co., Ltd.
    Inventors: Michiaki Tominaga, Takao Taki, Toshiaki Matsumoto, Izumi Hanya, Takuma Imada, Kunihiko Matsuoka, Takuya Kishimoto, Yuko Uchiyama, Hiromasa Tsuneishi, Machiko Tsuji, Tania Valdes-Gonzalez, Kentaro Tadano, Kyoko Kameda
  • Patent number: 8900866
    Abstract: A method for forming a nerve graft includes the following steps. A carbon nanotube structure is provided. A hydrophilic layer is formed on a surface of the carbon nanotube structure. The hydrophilic layer is polarized to form a polar surface on the hydrophilic layer. A number of neurons are formed on the polar surface of the hydrophilic layer to form a nerve network. The neurons connect with each other.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: December 2, 2014
    Assignees: Tsinghua University, Hon Hai Precision Industry Co., Ltd.
    Inventors: Chen Feng, Li Fan, Wen-Mei Zhao
  • Patent number: 8900646
    Abstract: A method and composition for treating feedlot cattle in order to mask odor or pheromones given by cattle that trigger other cattle to mount them in a behavior pattern known as Buller Steer Syndrome, or to at least provide a scent which neutralizes that behavior.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: December 2, 2014
    Inventors: Danny Justman, Melissa Justman
  • Patent number: 8895087
    Abstract: A composition having a curcuminoid and an essential oil of turmeric. A composition having a curcuminoid and an essential oil of turmeric, wherein the essential oil is present in an amount sufficient to cause an enhancement of bioavailability of curcumin when the composition is administered to a human as compared to bioavailability of curcumin obtained upon administration of a composition prepared without adding essential oil to the curcuminoid. A method to prepare a composition having a curcuminoid and an essential oil of turmeric.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: November 25, 2014
    Assignee: Arjuna Natural Extracts, Ltd
    Inventor: Benny Antony
  • Patent number: 8895080
    Abstract: Embodiments of the invention provide eyelid preparations, methods, and kits, for treating ocular conditions. The eyelid preparations comprise a mixture of tea tree oil and sea buckthorn oil in a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: November 25, 2014
    Assignee: OCuSOFT, Inc.
    Inventors: Nat Adkins, Jr., Cynthia Barratt
  • Patent number: 8883461
    Abstract: The present invention discloses a process for producing purple-blue natural pigment containing violacein and its derivative (deoxyviolacein) using Chromobacterium sp. NIIST-CKK-01 (MTCC 5522, NCIM 5341; Genbank Accession No. FJ982784). The method comprises the steps of maintaining and growing the bacterium in a specific medium under defined conditions of pH, temperature and agitation. At the end of incubation, pigment and biomass is separated from the culture broth, pigment is recovered from the biomass through solvent extraction and finally pigment is concentrated by drying.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: November 11, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventor: Krishnakumar Bhaskaran
  • Patent number: 8877259
    Abstract: Disclosed is a topical skin cleanser comprising Silybum marianum fruit extract, Momordica grosvenorii fruit extract, and a cosmetic vehicle comprising at least 50% by weight of the composition of water and disodium EDTA, glycerin, phenoxyethanol, triethanolamine, 3-Iodo-2-propynyl butyl carbamate, and benzyl alcohol.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: November 4, 2014
    Assignee: Mary Kay Inc.
    Inventors: Tiffany Florence, Michelle Hines, David Gan, Barbara Durkee
  • Patent number: 8871279
    Abstract: This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of cancer by administering the herbal composition PHY906 in combination with one or more chemotherapeutic compounds to a mammal undergoing such chemotherapy.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: October 28, 2014
    Assignee: Yale University
    Inventors: Yung-Chi Cheng, Shwu-Huey Liu, Zaoli Jiang, Robert Tilton
  • Patent number: 8865434
    Abstract: A method of producing saccharides containing glucose as the major constituent by degrading at least one selected from the group consisting of cellulose and hemicellulose with a cellulose saccharifying enzyme is provided. The method includes the steps of: mixing a cellulose material and a solution containing cellulose saccharifying enzyme to prepare a mixture; and saccharifying the cellulose material with the saccharifying enzyme. A gross energy density Y (W/m3) subjected to the mixture and a substrate concentration X (w/v%) of the cellulose material to the enzyme solution satisfy a formula (1) below during the step of saccharifying. Y??0.0125X2+1.195X+23.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: October 21, 2014
    Assignee: JGC Corporation
    Inventors: Daisuke Taneda, Makoto Ikeo
  • Patent number: 8859020
    Abstract: Disclosure provides a formulation of curcuminoid with essential oil of turmeric to enhance the bioavailability of curcumin and to augment the biological activity of curcumin, wherein curcumin is the main constituent of curcuminoid and wherein Ar-turmerone is the main constituent of the essential oil of turmeric. An application of curcuminoid with essential oil of turmeric to enhance the bioavailability of curcumin for oral supplementation against a variety of diseases and method of doing the same is provided.
    Type: Grant
    Filed: October 4, 2012
    Date of Patent: October 14, 2014
    Inventor: Benny Antony
  • Patent number: 8859237
    Abstract: Described is a new stand-alone diguanylate cyclase polypeptide having a GGDEF motif and a mutated I-site that does not bind c-di-GMP. We demonstrate that the production yield of c-di-GMP and analogues was significantly increased by mutation of a conserved residue in the putative regulatory I-site.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: October 14, 2014
    Assignee: Nanyang Technological University
    Inventors: Zhao-Xun Liang, Feng Rao
  • Patent number: 8852934
    Abstract: According to embodiments, a method of producing insulin-producing tissues (IPTs) by culturing comprises: preparing non-endocrinal epithelial cells (NEECs) and vascular endothelial cells (VECs), which have been isolated or originated from postnatal pancreata, preferably by capturing of NEECs by collagen; culturing in vitro the NEECs and the VECs at least partly separately from each other; and then generating in vitro a tissue complex (IPTs) that contains both the NEECs and the VECs. In another embodiment, the native islet cells are seeded on a monolayer of VECs that have preferably been separately cultured and purified. In a further embodiment, a method of enriching NEECs comprises: culturing NEECs adhering to a container or substrate; removing NEECs by treating with a tissue-dissociation enzyme to leave left-over cells (LOCs) still attached on the container or substrate; and culturing NEECs in a medium conditioned by, or in the presence of the LOCs.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: October 7, 2014
    Assignee: Kyoto University
    Inventors: Jun Kanamune, Yasuhiro Iwanaga, Shinji Uemoto, Yoshiya Kawaguchi
  • Patent number: 8852919
    Abstract: A microfluidic apparatus, method, and associated applications utilize and apply to a formalin-fixed paraffin-embedded (FFPE) tissue sample and performing a liquid-liquid extraction to remove the paraffin from the tissue sample prior to a nucleic acid purification step. A microfluidic device includes a dedicated liquid-liquid extraction process vessel, a nucleic acid purification process component, and a nucleic acid amplification reactor. A liquid-liquid extraction and nucleic acid purification kit includes a microfluidic device capable of performing both a liquid-liquid extraction process and a nucleic acid purification process, including a dedicated liquid-liquid extraction process vessel, an immiscible liquid or a precursor phase thereof disposed in the vessel, a nucleic acid purification process component, a nucleic acid amplification reactor fluidically, and a supply of reagents suitable to enable the liquid-liquid extraction process and the nucleic acid purification process.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: October 7, 2014
    Assignee: Rheonix, Inc.
    Inventor: Peng Zhou