Patents Examined by Patricia Patten
  • Patent number: 6680075
    Abstract: Disclosed are a natural invigorating tea and a method for preparing the same. The natural invigorating tea may be in the form of powder, liquid, or granules and is made of parasitic herb, and alder and/or schizandrae fructus, optionally supplemented with torilis fructus and/or polygalae japonica herba. Taking of the tea at least twice a day, morning and evening, invigorates human body.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: January 20, 2004
    Inventor: Jong-Hyun Nam
  • Patent number: 6676978
    Abstract: A method for isolating a mixture of anthocyanins, bioflavonoids and phenolics from an edible berry using adsorbent resins which are regenerable for reuse is described. The mixture with a consumable carrier is particularly useful in foods and as a dietary supplement or nutraceutical product.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: January 13, 2004
    Assignee: Board of Trustees of Michigan State University
    Inventor: Muraleedharan G. Nair
  • Patent number: 6676933
    Abstract: A pharmaceutical composition contains mosapride, pancreatin and optionally simethicone and is used for treating, preventing or alleviating the symptoms of a gastrointestinal disorder. The pharmaceutical composition is provided in an oral dosage form for administration to a subject.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: January 13, 2004
    Assignee: Osmotica Corp.
    Inventors: Juan A. Vergez, Marcelo A. Ricci, Joaquina Faour
  • Patent number: 6669967
    Abstract: A method for the treatment of disorders related to normal hormonal variations in women during fertile, peri- and post-menopausal age, by the administering of a composition comprising, as active ingredients, a water and/or fat-soluble cytosolic extract of pollen and optionally pistils, optionally combined with Royal Jelly and vitamin E.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: December 30, 2003
    Assignee: Natumin Pharma AB
    Inventors: Kaj Winter, Christer Hedman, Lars Kärnerud
  • Patent number: 6663894
    Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: December 16, 2003
    Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis Pigmentosa
    Inventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loic Van Den Berghe, Sebastian Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
  • Patent number: 6660831
    Abstract: Methods for aiding in the diagnosis of dysautonomic disorders and dysautonomic conditions and methods for treating individuals diagnosed as having a dysautonomic disorder or a dysautonomic condition. In one aspect, a diagnosis method comprising analyzing a stool sample of an individual for the presence of a biological marker wherein the quantity of the biological marker is an indication of whether the invidual has, or can develop, a dysuatonic disorder or dysautonomic condition, as well as a therapuetic method for treating a dysautonomic disorder or dysautonomic condition by administration of, e.g., secretin, neuropeptides, peptides and/or digestive enzymes.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: December 9, 2003
    Inventor: Joan M. Fallon
  • Patent number: 6656914
    Abstract: A method for inhibiting a tumor in a mammal using a composition comprising an anthocyanin or cyanidin from a berry is described. The method involves using the composition in an amount and for a time to inhibit the tumor. The composition can include other antitumor agents.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: December 2, 2003
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Leslie D. Bourquin, Navindra P. Seeram, Soo-Young Kang
  • Patent number: 6654120
    Abstract: A control reference material for the measurement of cells and crystals that are present in synovial fluid at different pathognomic conditions. Several possible suspending buffers for the control, its methods of preparation and a method for using these controls for analyses are provided. These controls are less costly and more readily available in greater quantities than current controls prepared from normal human synovial fluid as the suspending base.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: November 25, 2003
    Assignee: Quantimetrix Corporation
    Inventor: Robert W. Ban
  • Patent number: 6638540
    Abstract: The present invention is concerned with nutritional or pharmaceutical compositions containing a plant extract or concentrate selected from the group consisting of allium (leek), aethusa (dog parsley), petroselium (parsley) and brassica (cabbage) extracts and concentrates. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: October 28, 2003
    Assignee: Universitat Bern
    Inventor: Roman Conrad Mühlbauer
  • Patent number: 6627232
    Abstract: A cocoa extract which is rich in procyanidin monomers and oligomers is made by extracting de-fatted, unroasted, unfermented cocoa beans with organic solvents. The yield of procyanidins in an extract varies with type of solvent used, extraction temperature, extraction pH and whether or not the solvent is an aqueous solvent solution. Extraction parameters can be optimized to increase procyanidin yield, and different conditions and/or solvents result in the preferential extraction of the higher or lower oligomers. A preferred extraction method is counter-current extraction method.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: September 30, 2003
    Assignee: Mars Incorporated
    Inventors: John F. Hammerstone, Jr., Mark J. Chimel
  • Patent number: 6617161
    Abstract: A chemically defined-serum free growth medium for the in vitro and ex vivo of cells and cell lines. The medium consists of about a one to one ratio (v/v) of two basal growth media containing &agr;-ketoglutarate, insulin, transferrin, selenium, bovine serum albumin, linoleic acid, ceruloplasmin, cholesterol, phosphatidyl-ethanolamine, &agr;-tocopherol acid succinate, reduced glutathione, taurine, triiodothyronine, hydrocortisone, parathyroid hormone, L-ascorbic acid 2-sulfate, &bgr;-glycerophosphate, PDGF, EGF and FGF. Chondrocytes, when cultured in this medium in the presence of a cartilage derived morphogenetic protein or bone morphogenetic protein, retain their cartilaginous phenotype.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: September 9, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Frank P. Luyten, Ludwig Erlacher
  • Patent number: 6616928
    Abstract: The present invention relates to an active oxygen scavenging agent and a cancer chemopreventing agent both comprising a dried Grifola, a dry Grifola powder and/or a Grifola extract, and to a food or animal feed comprising the active oxygen scavenging agent or the cancer chemopreventing agent.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: September 9, 2003
    Assignee: Yukiguni Maitake Co., Ltd.
    Inventors: Kenji Tazawa, Yasuo Odaira, Masataka Watanabe
  • Patent number: 6610330
    Abstract: The invention relates to an anti-diabetic agent obtained from the plant Humboldtia decurrens, an anti-diabetic formulation comprising an effect amount of the extract obtained from the plant Humboldtia decurrens optionally together with additives, a process for obtaining the anti-diabetic agent, and a method for treatment of diabetes.
    Type: Grant
    Filed: November 6, 2001
    Date of Patent: August 26, 2003
    Assignees: Council of Scientific & Industrial Research, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala Institute for Research Training and Development Studies of Scheduled Castes and Scheduled Tribes
    Inventors: Janaswamy Madhusudana Rao, Mangattu Achutankunju Sumathykutty, Gopalan Vijay Nair, Alathur Damodaran Damodaran, Kodandaraman Rathinam, Rajagopal Sivakumar, Kottilil Mohan Das, Narayanapillai Viswanathan Nair
  • Patent number: 6610331
    Abstract: A method and kit for enhancing the natural fertility process. The kit includes a vaginal douche that is used prior to intercourse to enhance the sperm transportation and sustaining properties of the cervical mucous. The douche contains a balanced electrolyte solution, polysaccharides, and pH buffers. The kit also includes nutriceuticals specifically formulated for both the male and female which include amino acids, minerals, vitamins, herbs, phytoestrogens, and antioxidants along with a specified dosing regimen. A basal body temperature thermometer and chart is provided with instructions to confirm when and if ovulation will/did occur. Commercially available urinary chemical reagent strips are provided with instructions so as to predict/confirm if and when ovulation will occur. A lubricating medium will also be provided and utilized at the time of intercourse which is nonspermicidal and which contains polysaccharides which influence natural sperm motility.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: August 26, 2003
    Inventors: Scott M. Sweazy, Jill A. Sweazy
  • Patent number: 6610292
    Abstract: An enzymatic method is provided for treating ophthalmic disorders of the mammalian eye. Prevention of neovascularization and the increased rate of clearance from the vitreous of materials toxic to the retina is accomplished by administering an amount of hyaluronidase effective to liquefy the vitreous humor of the treated eye without causing toxic damage to the eye. Liquefaction of the vitreous humor increases the rate of liquid exchange from the vitreal chamber. This increase in exchange removes those materials and conditions whose presence causes ophthalmological and retinal damage.
    Type: Grant
    Filed: November 19, 1999
    Date of Patent: August 26, 2003
    Assignee: ISTA Pharmaceuticals, Inc.
    Inventors: Hampar Karageozian, Vicken Karageozian, Maria C. Kenney, Jose L. G. Flores, Gabriel Arturo Carpio Aragon, Anthony B. Nesburn
  • Patent number: 6601580
    Abstract: Methods for reducing, partially preventing or completely preventing nitric oxide (NO) inhalation-related impairment of HPV in a mammal are disclosed. The methods include administering a therapeutically effective amount of NO by inhalation, and co-administering an effective amount of an anti-reactive oxygen species (anti-ROS) agent, e.g., N-acetylcysteine, or a leukotriene blocker. Methods for reducing, partially preventing or completely preventing loss of pulmonary vasodilatory responsiveness to NO inhalation in a mammal are also disclosed. The methods include administering a therapeutically effective amount of NO by inhalation, and co-administering an effective amount of an anti-ROS agent a therapeutically effective amount of a leukotriene blocker.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: August 5, 2003
    Assignee: The General Hospital Corporation
    Inventors: Kenneth D. Bloch, Fumito Ichinose, Warren M. Zapol
  • Patent number: 6599541
    Abstract: The invention provides a novel composition useful in the treatment of resistant bacterial infections, said composition comprising an extract obtained from Azadiracta indica or Melia azadirachta and an effective amount of an antibiotic or chemotherapuetic antibacterial drug. Further, the invention provides a method for the treatment of resistant bacterial infections. The invention also provides a process for the preparation of the composition of the invention.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: July 29, 2003
    Assignee: Dabur Research Foundation
    Inventors: Narasimha Baba Brindavanam, Chandra Kant Katiyar, Dasalukunte Bhimrao Ananta Narayana
  • Patent number: 6589569
    Abstract: A medicinal composition has been created that is useful in the treatment of PMS in human females who experience adverse PMS symptoms. The composition is comprised of an extract of asparagus racemosus. The composition preferably includes about eighty-five parts Asparagus racemosus and about five parts each of Withania sominifera, Pedalium murex, and Tinospora cordifolia. The active component of the Asparagus racemosus is saponin glucoside (A4). Preferably, the composition is administered in capsular form with each capsule containing about one-half gram of the composition. Two of these capsules are taken three times a day.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: July 8, 2003
    Inventor: Kirpal S Dhaliwal
  • Patent number: 6586016
    Abstract: The present invention provides Chinese herbal compositions, ST 188L and method for prevention and treatment of cancers and infectious diseases. The Chinese herbal compositions comprise a formulation prepared ratably from a group of herbal plants consisting essentially of Ecchinops grijissii, Cirsium segetum Bge, Solanum indicum Linn, Lonicerae flos, and Zizyphi fructus. ST188L appeared to be activated in vivo to stimulate the activity of NK cells and LAK cells as shown by the increases in cytolytic activity of peripheral blood mononuclear cells isolated from volunteers after intake of ST 188L toward target cells, such as K562, Daudi, HepG2 and HBV transfected HepG2-2215 in a dose dependent manner. ST 188L has been proven to be effective on eradicating malignancy in a cancer patient by enhancing said patients' endogenous immune system to keep said patient cancer free for more than ten years.
    Type: Grant
    Filed: September 13, 2001
    Date of Patent: July 1, 2003
    Assignee: Sagittarius Life Science Corp.
    Inventors: Yi Ming Tsai, Kou Mark Hwang, Suying Liu
  • Patent number: 6576271
    Abstract: A method for inhibiting cyclooxygenase enzymes and inflammation in a mammal using a cherry or cherry anthocyanins, bioflavonoids and phenolics is described. In particular a mixture including the anthocyanins, the bioflavonoids and the phenolics is described for this use.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: June 10, 2003
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Muraleedharan G. Nair, Haibo Wang, Gale M. Strasburg, Alden M. Booren, James I. Gray