Abstract: A continuous volume detection system for a flexible venous reservoir in a cardiopulmonary bypass circuit is described. The volume detection system is based on a pressure measurement that is manipulated via application of fluid mechanics. Next-generation cardiopulmonary bypass system controllers may use this data to control the volume contained in the flexible venous reservoir.

Abstract: Blood processing systems and methods convey blood cells from a blood cell source into a blood component collection flow channel that includes a blood cell storage container and an in-line filter to remove leukocytes from blood cells before entering the blood cell storage container. The systems and methods also convey additive solution from an additive solution source into the blood component collection flow channel. The systems and methods alternate the conveyance of blood cells through the filter with the conveyance of additive solution through the filter.

Abstract: The invention relates to a method for determining blood volume during extracorporeal blood circulation, which is based on measuring the propagation rate or propagation time of the pulse waves propagating in the extracorporeal circulation system. The invention preferably involves the measurement of the propagation rate or propagation time of the pulse waves generated by the blood pump, which is placed in arterial branch of the blood line. The device for determining blood volume can make use of the pressure sensor, which is placed in the venous branch of the blood line and which is already provided in prior art blood treatment devices. As a result, the amount of equipment required is relatively low.

Abstract: A connector according to the invention comprises a hollow needle fastened to a body. A first tubular receptacle provided with a first foil surrounds a first end section of the needle. A second tubular receptacle provided with a second foil surrounds a second end section of the needle. The tubular receptacles are able to slide on the body. The holding sleeve moves the body toward the first foil over a first piercing stroke to pierce it, and then moves the second foil toward the body over a second piercing stroke to pierce it. In this way there may be obtained simultaneous piercing of the foils and foils or stoppers of containers such as flasks or sachets pressed against the foils, to provide a connection under optimum conditions of sterility.

Abstract: A method of alerting medical personnel of a problem during hemodialysis includes providing an active, fail-to-safe site sensor for a fistula needle at an access site during hemodialysis; and automatically alerting medical personnel of a problem during hemodialysis using the active, fail-to-safe site sensor during at least the following: failing of the active, fail-to-safe site sensor; insufficient powering to the active, fail-to-safe site sensor; partial fistula needle dislodging from the access site; and complete needle dislodging from the access site.

Abstract: Systems and methods manually process blood and blood components in sterile, closed environments, which further condition the blood components for subsequent pathogen inactivation processes. The systems and methods mate the manual collection of random donor platelet units with the creation of larger therapeutic doses of platelets targeted to undergo pathogen inactivation prior to long term storage and/or transfusion.