Patents Examined by Pili Hawes
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Patent number: 7147869Abstract: A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.Type: GrantFiled: December 6, 2001Date of Patent: December 12, 2006Assignee: Altana Pharma AGInventors: Rango Dietrich, Hartmut Ney, Rudolf Linder
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Patent number: 7141248Abstract: Methods of producing an intraocular lens include introducing a solution into a lens forming enclosure, wherein the solution comprises discrete crosslinkable units of a size small enough to provide an optically clear solution while contributing to a high refractive index of at least 1.3, performing crosslinking between the units of the solution, and thereby forming a solid lens in the enclosure, optionally under a forming pressure.Type: GrantFiled: May 23, 2003Date of Patent: November 28, 2006Assignee: AMO Groningen BVInventors: Kenneth A. Hodd, Keith Alfred Dillingham, Jacqueline de Groot
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Patent number: 7132111Abstract: The present invention includes a method for making a formulation for treating mucosal discontinuities, comprising: providing phenolic compounds and treating the purified phenolic compounds with sulfuric acid to make sulfonic acids and sulfonate salts. The present invention also includes formulations prepared by the method.Type: GrantFiled: May 21, 2003Date of Patent: November 7, 2006Assignee: Epien Medical, Inc.Inventor: Michael Basara
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Patent number: 7122203Abstract: The present invention is directed to pharmaceutical formulations containing 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxypheny)benzo[b]thiophene or a salt thereof; stabilized to oxidation or other forms of decomposition by incorporation of a stabilizing agent selected from methionine, acetylcysteine, cysteine or salts thereof.Type: GrantFiled: April 30, 2001Date of Patent: October 17, 2006Assignee: Eli Lilly and CompanyInventors: Fadia Najjar Bashore, Kerry John Hartauer, Michael Dean Minnett, Eugene Clark Rickard, Cheryl Ann Tingle
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Patent number: 7101567Abstract: Preparations whereby two or more drugs can be released separately at appropriate speeds depending on the disease or the release behaviors of one or more drugs can be precisely controlled, which consist of an outer layer wherein a water-soluble drug is dispersed in a carrier made of a biologically non-degradable and hydrophobic polymer material, and one or more inner layers wherein a water-soluble drug, differing in kind or concentration from the one contained in the outer layer, is dispersed in a carrier made of a biologically non-degradable and hydrophobic polymer material, and in which the outer and inner layers are concentrically located in diametral direction of rod-like preparations and both or one of the ends in the axial direction are opened so as to directly come into contact with the environment.Type: GrantFiled: May 19, 1999Date of Patent: September 5, 2006Assignee: Dainippon Sumitomo Pharma Co., Ltd.Inventors: Akihiko Sano, Masako Kajihara, Toshihiko Sugie
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Patent number: 7087240Abstract: Devices and methods for treatment of erectile dysfunction and methods of manufacture and of use are provided. The devices include filmogenic material, a therapeutic agent, a permeation enhancer, and other ingredients. An embodiment of the device includes a backing and a release liner.Type: GrantFiled: June 25, 1999Date of Patent: August 8, 2006Assignee: Lavipharm Laboratories Inc.Inventor: Spiros Fotinos
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Patent number: 7067150Abstract: The present invention provides oral delivery systems for functional ingredients, such as drugs, nutritional supplements, botanicals, and vitamins. The delivery systems comprise an ingestible matrix within which the functional ingredient(s) are substantially uniformly and completely dispersed and in which degradation of the functional ingredient(s) is minimised. The matrix comprises 1) one or more carbohydrate; 2) one or more sugar, sugar syrup and/or sugar alcohol; 3) one or more hydrocolloid; 4) one or more polyhydric alcohol; 5) one or more source of mono- or divalent cations, and 5) water. The combination of carbohydrate and hydrocolloid in the matrix ensures that the delivery system readily retains the solvent component and thereby prevents separation of the solvent from other components of the matrix. The invention also provides methods of preparing and using the delivery systems.Type: GrantFiled: March 25, 2003Date of Patent: June 27, 2006Assignee: Scepter Holdings, Inc.Inventors: Michael Farber, Jonathan Farber
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Patent number: 7037525Abstract: The invention relates to formulations, e.g. film-coated tablets containing oxcarbazepine and to processes for the production of said formulations. The film-coated tablets have a tablet core comprising a therapeutically effective dose of oxacarbazepine being in a finely ground form having a mean particle size of from 4 to 12 ?m (median value), and a hydrophilic permeable outer coating.Type: GrantFiled: May 5, 2003Date of Patent: May 2, 2006Assignee: Novartis AGInventor: Burkhard Schlütermann
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Patent number: 7018653Abstract: The present invention relates to a novel method for the preparation of a solid dosage form of desmopressin, or a pharmaceutically acceptable salt thereof, comprising providing a desmopressin containing granulate suitable for compression to a pharmaceutically acceptable tablet, as well as to solid dosage forms, preferably tablets, obtainable by said method.Type: GrantFiled: December 29, 2003Date of Patent: March 28, 2006Assignee: Ferring B.V.Inventors: Kristen Wannerberger, Hans Lindner, Lars-Erik Olsson, Ann Elisabeth Svensson
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Patent number: 7011847Abstract: Pharmaceutical compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more bisphosphonic acids or salts thereof, a seal coating surrounding the active coating and an enteric coating surrounding the seal coating. Alendronic acid and alendronate sodium trihydrate are the preferred active ingredients. The composition may be provided in the form of pellets in a capsule or Peltabs. The invention further provides methods for the treatment of disorders caused by the abnormal dissolution or deposition of calcium salts using the inventive compositions.Type: GrantFiled: October 16, 2003Date of Patent: March 14, 2006Assignee: U & I Pharmaceuticals Ltd.Inventors: Amar Lulla, Geena Malhotra
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Patent number: 6984403Abstract: The present invention is related to an oral dosage form comprising an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a glyceride which comprises glyceryl monobehenate, glyceryl dibehenate, glyceryl tribehenate, or a mixture thereof and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule.Type: GrantFiled: January 23, 2004Date of Patent: January 10, 2006Assignee: Pfizer Inc.Inventors: Timothy A. Hagen, Julian B. Lo, Avinash G. Thombre, Scott M. Herbig, Leah Elizabeth Appel, Marshall David Crew, Dwayne Thomas Friesen, David Keith Lyon, Scott Baldwin McCray, James Blair West