Abstract: Filter elements for perfusion systems and methods are provided. A filter element sheet includes a microporous membrane having a mean pore size of at least about 0.65 ?m and a feed spacer comprising woven fibers and having an open area of at least about 35%. The filter element sheet can be arranged within a filter element, for example, in a spiral-wound format or in a cassette format. A perfusion system includes at least one filter element and a pump configured to control flow of a liquid feed through the at least one filter element.

Abstract: The present invention discloses a sludge anaerobic fermentation treatment method with simultaneously enhanced acid production and phosphorus removal. The method includes steps of: (1) adding waste activated sludge into an anaerobic reaction system, with a concentration of a total suspended solid (TSS) of 10000-15000 mg/L; (2) maintaining a pH value of the waste activated sludge at 10±0.1; adding powdery magnetite of 0.3-0.9 g/gVS S. Compared with simple alkaline conditions, in the method of the present invention, an accumulation amount of short chain fatty acids (SCFAs) in a fermentation broth is increased by 20%, and a content of orthophosphoric acid is reduced by 10%. The method can further improve the enhancing effect by using sulfuric acid to modify the magnetite, the accumulation amount of SCFAs can be increased by 36.7% at most, and the content of phosphorus and refractory organic substances can be reduced by 32.4% and 40.4% at most, respectively.

Abstract: An artificial kidney and its supportive device comprising a catheter having an internal semipermeable membrane tube to act as an artificial kidney. Said catheter comprising a proximal portion having a semipermeable membrane tube, a blood/infusion lumen, a dialysate lumen and side holes, while a distal portion having a dual septa port assembly. Said supportive device comprising a device house with its cover that covers its internal cavity that includes sorbent bags with different sizes and arrangement, a screen, buttons, set knobs, two contactless conductivity cells, bidirectional rotary pumps, rotary valves, pressure sensors, a slot for memory card, a temperature sensor, scales, an IV pole and a blood leak detector.

Abstract: Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.

Abstract: The disclosure relates to systems and methods for controlling the sodium and bicarbonate concentrations in a dialysate. The systems and methods can use conductivity sensors to control the addition of water and bicarbonate to accurately control the final concentrations of both sodium and bicarbonate.

Abstract: A movable seal for interfacing between a first surface and a second surface includes a floating portion attached to a non-floating portion by a flexible coupling portion, wherein the non-floating portion is coupled to the first surface by nesting in a groove on the first surface, and wherein the non-floating portion forms a seal between the first and second surfaces when the first surface moves relative to the second surface in a first direction, and wherein the non-floating portion does not form a seal between the first and second surfaces when the first surface moves relative to the second surface in a second opposite direction.

Abstract: A water treatment system for a poultry chiller including a chiller tank is described herein. The system includes a float holding tank at a downstream section of the chiller tank; a fan at the downstream section of the chiller tank that is configured to blow float formed on a surface of the water in the chiller tank into the float holding tank; and a float removal mechanism at the float holding tank that is configured to remove the float from the float holding tank. Related methods are also described.

Abstract: Disclosed herein is a single pass cross flow diafiltration system comprising: a filtration module having; two or more filtration segments fluidly connected in series, each having an upstream side and a downstream side; wherein each filtration segment comprises hollow fiber filter membranes, and wherein each filtration segment has a selected length; wherein the hollow fiber filter membranes of each filtration segment have a selected inner diameter; wherein the selected inner diameter of each filtration segment may be the same or different, provided that at least one selected inner diameter differs from another selected inner diameter, and provided that the two or more filtration segments are arranged such that no selected inner diameter in a given filtration segment is larger on the upstream side; one or more pumps, mounted to urge fluid flow; and one or more points of introduction of a diadiluent, each of said points of introduction being fluidly connected to an upstream filtration segment.

Abstract: A micro alternating tangential flow (microATF) perfusion filter includes a hollow cylinder having a proximal end and a distal end. The proximal end is connected in series to a permeate chamber, followed by a retentate chamber. The proximal end either (i) terminates in or at the permeate chamber, or (ii) terminates in or at the retentate chamber. The portion of the proximal end within the permeate chamber, in a case of (ii), possesses at least one opening allowing fluid communication between an inside of the hollow cylinder and the permeate chamber. The microATF perfusion filter further includes an inlet, positioned over the retentate chamber, for communication with a source of positive or negative pressure, and an outlet, positioned in a wall of the permeate chamber, which can be connected to a check valve, which, in turn, can be connected to a hydrophobic fluid vent filter.

Abstract: Disclosed herein are membrane separator modules. The membrane separator module includes a plurality of hollow fibers arranged as an annular shaped bundle defining a bore, wherein each of the plurality of hollow fibers includes a lumen; a first manifold attached to a first end of the plurality of hollow fibers and a second manifold attached to a second end of the plurality of hollow fibers; a fluid inlet port disposed on the first manifold and in fluid communication with a first interior volume thereof, and a fluid outlet port disposed on the second manifold and in fluid communication with a second interior volume thereof, wherein a fluid path is defined through the inlet port, the first interior volume, the lumens of the plurality of hollow fibers, the second interior volume, and the outlet port; and an impeller operable to drive fluid flow over exterior surfaces of the plurality of hollow fibers.

Abstract: A thermally reflective membrane apparatus comprises a housing structure, and a thermally reflective membrane contained within the housing structure. The thermally reflective membrane comprises a semipermeable structure, and a porous, thermally reflective structure physically contacting the semipermeable structure. The porous, thermally reflective structure comprises discrete thermally reflective particles, and a binder material coupling the discrete thermally reflective particles to one another and the semipermeable structure. A fluid treatment system and method of treating a fluid are also described.

Abstract: A funnel-less filtration device that attaches directly to a storage container such as a cell culture media bottle. The device includes a filter collar containing one or more membranes, an inlet with a coupling device for attaching the filter device to a supply of liquid to be filtered, an outlet at a lower portion of the collar, a vacuum port in the collar below the membrane(s) and a filtered vent in the collar above the membrane(s). Optionally, the device may include a filtrate reservoir attached to the outlet, preferably by a threaded connection. Optionally, the upper opening to the filter collar is selectively and removably sealed with a lid until used. The lid is then removed the filter device inverted over a storage container such as cell culture media bottle and the two are attached via the upper opening of the filter collar. The assembly is then inverted so the supply container is above the filter device.

Abstract: A system for separating a solvent includes a first mixing tank comprising a waste solvent feed and a reactant feed; a first filter comprising a nanofiltration membrane; a distillation column or an evaporator; a condenser or cooler; and a pervaporation membrane. A method for separating a solvent includes mixing a waste solvent with a reactant to cause precipitation or complexing and forming a mixture; filtering the mixture using a nanofiltration membrane and forming a permeate; distilling or evaporating the permeate to form a concentrated solvent; condensing or cooling the concentrated solvent to below a boiling point of solvents in the concentrated solvent; and filtering the concentrated solvent using pervaporation to form a purified solvent. The system and method may be used to separate and purify a solvent without creating thermal degradation products.

Abstract: The present invention relates to a groundwater circulation well system with pressure-adjustable hydrodynamic cavitation, including a circulation well body, a sucked and injected water circulation assembly and a hydrodynamic cavitator. The sucked and injected water circulation assembly is based on a water suction and injection pump. The hydrodynamic cavitator is provided, inside a vortex chamber, with a vortex water inlet column capable of changing a water passing aperture. The hydrodynamic cavitator is capable of changing a bubbling pressure and a breaking pressure of hydrodynamic cavitation bubbles in the vortex water inlet column. The hydrodynamic cavitator generates vortices in the circulation well body to accelerate uniform mixing of a remediation agent and the groundwater. Energy from collapsing and bursting of the hydrodynamic cavitation bubbles activates the remediation agent such that contaminants in the groundwater are efficiently degraded.

Abstract: A priming subsystem of a cell processing system carries out a method for priming a spinning membrane separator having an inlet and first and second outlets. The method includes opening a first selectable junction disposed between a priming fluid container and the inlet to open a path between the priming fluid container and the inlet, operating a first pump coupled to the first outlet to draw priming fluid from the priming fluid container into the spinning membrane separator, and closing the first selectable junction and a second selectable junction coupled to the second outlet after drawing the priming fluid into the spinning membrane separator. The method further includes operating the first pump after the first selectable junction is closed to draw a vacuum, and opening the first selectable junction after drawing the vacuum.

Abstract: The invention relates to filtration system (20), comprising a tank (40) filled at least partly with water to be filtered, and at least one filtration module (30), the at least one filtration module (30) comprising at least one filter membrane (10) for filtering the water comprising a substrate (12) which is penetrated by at least one capillary (16), and at least one filtrate pipe (32) for drawing filtered water out of the tank (40), whereat the at least one filtration module (30) is arranged in the tank (40) such that the at least one filter membrane (10) is submerged at least partly in the water to be filtered. The at least one filtration module (30) is designed and arranged such that water to be filtered flows into the at least one capillary (16) and from the at least one capillary (16) through the substrate (12) into the filtrate pipe (32).

Abstract: The present inventions are directed to systems and methods to increase the removal of PFAS and other recalcitrant organic compound contaminants from water, and particularly ground and drinking water, using sub-micron powdered activated carbon.

Abstract: As pellets grow from seed/sand in a fluidized bed pellent reactor, the weight of the reactor is measured and the density of the contents of the reactor is calculated, and the input flow of untreated water, water treatment chemical, and seed/sand are adjusted to provide improved removal of water hardness while reducing fine particulates in the outflow of softened water from the reactor.

Abstract: The present disclosure describes a field flow fractionator including (1) a top plate assembly including (a) a first non-corrosive material, and (b) at least three fluid fittings machined (simpler) into the material, (2) a spacer, (3) a membrane, (4) a bottom plate assembly including (a) a second non-corrosive material, (b) a cavity machined into the second non-corrosive material, (c) a frit configured to be placed into the cavity, and (d) at least one bottom plate o-ring configured to seal the bottom plate assembly to the spacer, and (5) where the top plate assembly, the spacer, the membrane, and the bottom assembly define a separation channel. In an embodiment, the at least three fluid fittings including a fitting for an in-flow, a fitting for an out-flow, and a fitting for a cross-flow.

Abstract: A system and method for producing very high concentration brine streams from which commercially efficiently obtained minerals may be obtained is produced by a dual membrane brine concentrator system (DTRI Concentrator). The system includes a nano-filtration system which removes divalent ions from the seawater, a brine concentrator such as a hollow fine fiber forward osmosis system which receives and further concentrates the brine rejected from the nano-filtration system, a SWRO system which receives the NF system permeate and removes monovalent ions, and another brine concentrator which further concentrates the brine rejected from SWRO system. Various permeate and reject brine flow may be forwarded through the Dual Membrane Brine Concentrator system, and multiple stages of the system components may be used, to enhance brine concentration and improve system efficiency.