Patents Examined by Quynh-Nhu H. Vu
  • Patent number: 11911583
    Abstract: A therapeutic delivery device that provides a controlled release of high doses of a therapeutic agent in a local area, sustains the high dose controlled release with a percutaneous port for refilling the device, and is versatile for use with multiple types of therapeutic agents and/or implant systems. A rate determining/controlled release membrane is used to decrease the molecular mobility of the therapeutic compounds thereby controlling the therapeutic release profile. The therapeutic delivery device includes a body defining an internal reservoir for receiving a therapeutic agent and including a first membrane for providing a controlled release of the therapeutic agent to the surgical site, a port in fluid communication with the reservoir, a sleeve configured to encapsulate the body, and a rigid housing configured to support the body and a portion of the sleeve, the rigid housing configured to release the body and the sleeve after the body and the sleeve are anchored position relative to the surgical site.
    Type: Grant
    Filed: August 15, 2020
    Date of Patent: February 27, 2024
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Dustin Williams, Nicholas Ashton
  • Patent number: 11911584
    Abstract: A therapeutic delivery device that provides a controlled release of high doses of a therapeutic agent in a local area, sustains the high dose controlled release with a percutaneous port for refilling the device, and is versatile for use with multiple types of therapeutic agents and/or implant systems. A rate determining/controlled release membrane is used to decrease the molecular mobility of the therapeutic compounds thereby controlling the therapeutic release profile. The therapeutic delivery device includes a body defining an internal reservoir for receiving a therapeutic agent and including a first membrane for providing a controlled release of the therapeutic agent to the surgical site, a port in fluid communication with the reservoir, a sleeve configured to encapsulate the body, and a rigid housing configured to support the body and a portion of the sleeve, the rigid housing configured to release the body and the sleeve after the body and the sleeve are anchored position relative to the surgical site.
    Type: Grant
    Filed: August 15, 2020
    Date of Patent: February 27, 2024
    Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Dustin Williams, Nicholas Ashton
  • Patent number: 11904111
    Abstract: Disclosed herein are catheter assemblies (100) with a locator tip (134) proximal to the distal tip (112) of a catheter tube (110). The locator tip is sized to remain outside a female urethra and configured to allow the catheter tube to pass there through. As an example, the locator tip allows a woman using a urinary catheter to target her urethra without exposing the catheter tube to tissue until the urethra is located and insertion is initiated. This avoids infecting the urethra with a catheter tube that has been contaminated by bacteria around the urethra.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: February 20, 2024
    Assignee: ConvaTec Limited
    Inventors: David A. Donnelly, Julie Lambrethsen, Melanie Clutton
  • Patent number: 11904139
    Abstract: A processor-implemented method for closed-loop control in steady-state conditions includes determining, based on data including historical bolus information but excluding historical basal information, an amount of unmetabolized therapeutic substance in a patient; determining, based on a difference between a most recent measurement of a physiological condition of the patient and a target value for the physiological condition, a first amount or rate of a basal dosage for delivery to the patient; adjusting, based on the amount of unmetabolized therapeutic substance, the first amount or rate of the basal dosage to determine a second amount or rate of the basal dosage; and causing delivery of the second amount or rate of the basal dosage based on communicating the second amount or rate in a delivery command.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: February 20, 2024
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Benyamin Grosman, Louis J. Lintereur, Anirban Roy, Neha J. Parikh, Di Wu, Patrick E. Weydt, David Dunleavy, Ali Dianaty
  • Patent number: 11904136
    Abstract: An infusion set includes a base (221) and a flexible catheter (242) movable from a first catheter position disposed substantially entirely within the base (221) to a second catheter position in which a free end of the catheter (242) is disposed externally of the base (221). An introducer needle (234) is located within the catheter (242) and is movable between a first introducer needle position disposed substantially entirely within the base (221) and a second introducer needle position in which a free end of the introducer needle (234) is disposed externally of the bases (221). A spring (281) is activated to move the catheter (242) from the first to the second catheter position and the introducer needle (234) from the first to the second introducer needle position to facilitate insertion of the catheter (242).
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: February 20, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Cole Constantineau, Ryan Schoonmaker, Azadeh Khanicheh, Michel Bruehwiler, Judy Walish
  • Patent number: 11890405
    Abstract: A multi-port medical syringe comprises a port body, a syringe barrel, and a plunger. The port body comprises a cylindrical cavity with at least three ports. The three port are configured to connect the cylindrical cavity of the port body with three medical devices: a first port configured for attachment to a medical device such as an input fluid source; a second port configured for fluid transmission through a urinary catheter to a bladder of a human or animal; and a third port configured for attachment to a medical device such as a drainage fluid storage vessel. The syringe barrel comprises a cylindrical tube, at least a portion of which fits snugly inside the cylindrical cavity of the port body. The syringe barrel further comprises a syringe barrel port located proximate to, or in, an otherwise closed end of the syringe barrel.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: February 6, 2024
    Inventors: Albert A. Mikhail, Corollos Samir Abdelshehid
  • Patent number: 11878147
    Abstract: A method and system of providing a needle-less injector specifically configured to the needs of a user. The method includes assembling a needle-less injector by positioning an inner housing within the outer housing such that the inner housing is axially movable within the outer housing between a ready position and a firing position. The method further includes receiving a user selection of a delivery spring weight from a plurality of available delivery spring weights. Then a delivery spring having the selected spring weight is placed within the inner housing. The completed needle-less injector having a delivery spring with the selected weigh may then be delivered to the user. In alternative injector configurations, the user may also select one or more of a skin tensioning spring weight or a hammer length along with or instead of the delivery spring weight.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: January 23, 2024
    Assignee: PharmaJet Inc.
    Inventors: John Bingham, Robert Steinway
  • Patent number: 11878153
    Abstract: The present invention relates to a medicament delivery device comprising a housing, a compartment inside said housing for positioning a medicament container, an injection needle arranged to said housing, being connectable to said medicament container for delivering a dose of medicament, a manually operated activation mechanism for activating said device, an actuation mechanism operably connected to said activation mechanism and arranged to, upon activation of said activation mechanism, extend said injection needle from a first position inside said housing to a second position wherein a penetration of a patient is performed, a plunger rod arranged in said housing capable of acting on said medicament container for delivering a dose of medicament through said injection needle, a driver capable of acting on said plunger rod for delivering a dose of medicament.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: January 23, 2024
    Assignee: SHL MEDICAL AG
    Inventors: Eugen Koch, Cheng-Jung Yang, Laura Scholze
  • Patent number: 11872382
    Abstract: The present disclosure provides improved technologies relating to medical fluid heating systems and apparatus. In certain embodiments, the present disclosure relates to systems and apparatus for heating a fluid and, more particularly, for quickly and controllably heating a flow of blood or a blood product, for example, for infusion into a patient or for hyperthermia treatment. In particular, in a first aspect, the present disclosure is directed to a system and apparatus featuring single flow path fluid heating (“single path flow”). Moreover, in a second aspect, the present disclosure is directed to a system, apparatus, and related method for efficiently utilizing the thermal energy of an infusate stored in a reservoir (“slack time heating”). Furthermore, in a third aspect, the present disclosure is directed to a fluid heating system and apparatus featuring a vacuum release valve designed to prevent the undesired orientation of deformed inflow tubing (“vacuum release valve”).
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: January 16, 2024
    Assignee: Belmont Instrument, LLC
    Inventors: John Joseph Landy, III, George G. Brusard, Tristan Dion, Yeu Wen Tseng
  • Patent number: 11872360
    Abstract: A catheter system may include a catheter adapter and a catheter extending distally from the catheter adapter. The catheter system may include a needle assembly, which may include a plug, an outer housing, and an introducer needle. An outer surface of the plug may include multiple grooves, which may be in fluid communication with the introducer needle and configured to receive blood flashback. The grooves may include a first groove having a first surface-area-to-volume ratio, and a second groove having a second surface-area-to-volume ratio. The first surface-area-to-volume ratio may be less than the second surface-area-to-volume ratio. The first groove may have a greater volume than the second groove. The outer housing may seal a top of the first groove and a top of the second groove to prevent blood from flowing out the top of the first groove and the top of the second groove.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: January 16, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Bin Wang, Jonathan Karl Burkholz
  • Patent number: 11865309
    Abstract: A drug delivery device includes a reservoir for containing a medical product, a distally projecting end-piece having an outer surface and a total length measured along a longitudinal axis of said end-piece, said end-piece defining an axial passageway for the transfer of said medical product contained in said reservoir, wherein a gripping surface is provided on a portion of said outer surface, said portion being located in a distal region of said end-piece, the length of said portion representing at most 40%, preferably less than 33%, of the total length of the end-piece. An assembly includes such a drug delivery device and an adaptor intended to be mounted onto the end-piece.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: January 9, 2024
    Assignee: Becton Dickinson France
    Inventors: Stéphane Bonnet, Sylvain Hallynck
  • Patent number: 11865293
    Abstract: A body-fluid-and-medication leak-proof and closed medical connector has a first connecting assembly and a second connecting assembly. The first connecting assembly has a first sleeve and a first resilient valve. The first resilient valve tends to seal a first opening of the first sleeve. The second connecting assembly has a second sleeve and a second resilient valve. The second resilient valve tends to seal a second opening of the second sleeve. The two resilient valves can avoid leakage of the medication remaining in an injector and a vial, or remaining in a fluid infusion tube and a catheter. The two resilient valves also can seal in two directions to avoid leakage during connecting or separating the two connecting assemblies after supplying medication. Therefore, the transfer of the medication is more hygienic and safe, and the waste of medical resources is effectively reduced.
    Type: Grant
    Filed: November 20, 2020
    Date of Patent: January 9, 2024
    Inventor: Hsi-Chin Tsai
  • Patent number: 11865291
    Abstract: Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.
    Type: Grant
    Filed: May 2, 2023
    Date of Patent: January 9, 2024
    Assignee: Inari Medical, Inc.
    Inventors: Benjamin E. Merritt, John C. Thress, Paul Lubock
  • Patent number: 11844921
    Abstract: Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: December 19, 2023
    Assignee: Inari Medical, Inc.
    Inventors: Benjamin E. Merritt, John C. Thress, Paul Lubock
  • Patent number: 11839744
    Abstract: Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: December 12, 2023
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Benyamin Grosman, Louis J. Lintereur, Anirban Roy, Neha J. Parikh, Di Wu, Patrick E. Weydt, David Dunleavy, Ali Dianaty
  • Patent number: 11833329
    Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide techniques to implement functionality to receive blood glucose measurements over a period of time. An average of missing blood glucose measurement values may be maintained over a predetermined time period. A count of a number of missing blood glucose measurement values over a period of time may be established. A controller may calculate a divergence of the number of missing blood glucose measurement values over the period of time from the average of missing blood glucose measurements over the predetermined time period. Based on a value of the divergence, a determination that a safety constraint for delivery of insulin is to be reduced. The safety constraint may be reduced by a predetermined percentage. An instruction to deliver an insulin dosage may be generated according to the reduced safety constraint may be forwarded to a wearable drug delivery device.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: December 5, 2023
    Assignee: INSULET CORPORATION
    Inventors: Joon Bok Lee, Jason O'Connor, Yibin Zheng
  • Patent number: 11826536
    Abstract: An implantable percutaneous fluid delivery device is described that includes a subcutaneous base portion having one or more ports for supplying fluid to one or more implanted catheter devices and a percutaneous portion including an extracorporeal surface. The one or more ports of the subcutaneous base portion are accessible from the extracorporeal surface of the percutaneous portion. The subcutaneous base portion is at least partially insertable into a complementary recess formed in a bone, the subcutaneous base portion including one or more features for gripping the internal surface of such a complementary recess thereby directly anchoring the subcutaneous base portion to the bone. The device may be used to route fluid to neurosurgical catheters optionally via a router unit.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: November 28, 2023
    Assignee: RENISHAW (IRELAND) LIMITED
    Inventors: Paul David Fielder, Steven S Gill, Trefor Owen Lewis, Andrew Samuel Vick
  • Patent number: 11806460
    Abstract: A method includes, after an extracorporeal blood treatment, connecting a fluid source to an access line that is connected to a patient, and delivering a fluid from the fluid source to the access line to infuse blood from the access line to the patient, wherein the fluid delivered to the access line has a temperature from about 30 degrees Celsius to about 38 degrees Celsius.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: November 7, 2023
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: David Yuds, Samiullah K. Durrani, Martin Joseph Crnkovich
  • Patent number: 11793932
    Abstract: Provided is a medicine injection device capable of injecting a liquid medicine into a human body by using a medicine container configured to discharge the medicine contained therein along a designated path when a pressure is applied from outside, the medicine injection device including one or more medicine pressing units including one or more inflatable parts capable of being inflated by air to apply a pressure to the medicine container, and a first pumping unit capable of inflating one of the inflatable parts by including a first pump capable of generating air of a preset pressure, and a first pipe connectable to the one of the inflatable parts. According to the present invention, a risk of breakdown and a total manufacturing cost may be reduced due to a simple structure of the medicine injection device.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: October 24, 2023
    Assignee: IMPACT KOREA CO., LTD.
    Inventor: Moung Sook Lee
  • Patent number: 11793934
    Abstract: Disclosed is a medical system having a cartridge and an inserter. The cartridge includes a housing having an interior volume with a first guide within the interior volume. A cradle is disposed within the interior volume and is configured for mounting a medical appliance. The cradle includes a subcutaneous element and an insertion needle. The insertion needle is configured for being actuated to insert the subcutaneous element into a subject. The inserter includes a second guide configured to mate with the housing of the cartridge, and the first guide and second guide are configured to cooperate to guide the inserter into the interior volume along a guiding path defined by the first guide. The inserter is configured to removably attach to the cradle when guided into the interior volume. An insertion assembly is provided for actuating the insertion needle to insert the subcutaneous element into the subject.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: October 24, 2023
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Frank Deck