Abstract: An apparatus for applying electrical current to biological tissue such as skin, bone or muscle. A portable housing can be powered with a battery or attached cord leading to an alternating current or direct current power supply. An extendible arm permits a person to apply the treatment without assistance, and the housing can be operated with a single hand. An amplifier generates a high voltage direct current, and a controller generates a high quality square waveform output. Such waveform comprises an output to an electrode assembly in electrical contact with the biological tissue. The electrode assembly comprises at least one negative electrode and at least one positive electrode which generate an electric current through the biological tissue between the positive and negative electrodes. The electrode assembly is movable relative to the biological tissue so that the current path is continually changing.

Abstract: A method is provided of localizing a drug action where the drug is present throughout a vascular system. The localization occurs to within a volume of blood in a blood vessel, the vascular system having an initial temperature substantially within a first temperature range. A temperature-specific enzyme is delivered throughout a vascular system including a volume of blood in a blood vessel, the temperature-specific enzyme having a working temperature within a prespecified temperature range that does not substantially overlap the first temperature range. A heat transfer element is delivered to a blood vessel in fluid communication with the volume of blood. The temperature of the heat transfer element is adjusted such that the volume of blood in the blood vessel is heated or cooled to the prespecified temperature range. In this way, the action of the temperature-specific enzyme is substantially limited to the volume of blood heated or cooled.

Abstract: A surgical heating probe, comprising a handle, a radio-frequency-shielded neck extending from the handle and having an unshielded cathode and an unshielded anode present in the neck with a shielded insulating section of the neck located between the cathode and the unshielded anode, the neck being formed so that three points located in the cathode, the anode, and the insulating; section, respectively, form a triangular plane, the cathode, the anode, and the insulating section being spaced apart at distances adapted so that the cathode and the anode can closely approach opposite sides of an animal tendon, and an energy connector fixture located in the handle and adapted to connect a supply of heating energy to the anode and the cathode. The probe is particularly useful for the treatment of strabismus, and the invention involves the use of radio frequency heating to shrink extraocular tendons in the treatment of strabismus.

Abstract: The present invention is a method and apparatus for conveniently and removably sealing inlet ports within an inflatable thermal blanket. In accordance with the present invention a generally planar sheet of material having a plurality of resilient side extensions extending from a central body is used to close an inlet port within an inflatable thermal blanket. In accordance with the preferred invention, the generally circular portion of the central body has a diameter which is slightly smaller than the diameter of the inlet port. Preferably, for extensions extend from the central body each extension being generally circular. Each extension is preferably formed from the same material used to form the central body, and is sufficiently resilient to be easily flexed and to return to an essentially coplanar sheet when released.

Abstract: Low-power, low-voltage electrosurgical apparatus providing three current unipolar modes whose circuitry for generating the modulation signals needed to implement the three current modes employs no microcontroller but generates the modulation waveforms using a oscillator-binary counter and dual multiplexers, integrated components (ICs) that are of relatively low cost. Safety features can be incorporated by including a timer circuit cooperating with the binary counter to provide power to the IC components and avoid overheating of the apparatus. The oscillator-binary counter component is used to generate at plural outputs plural series of digital pulses at various frequencies, some of the pulse series being used to generate approximate sine-waves that can be employed for the cut/coag and hemo modes, and others of the pulse series being employed to operate a timer, indicator lights, and an audible warning system.

Abstract: A selective organ heat transfer device with deep irregularities in a turbulence-inducing exterior surface. The device can have a plurality of elongated, articulated segments, each having a turbulence-inducing exterior surface. A flexible joint connects adjacent elongated, articulated segments. An inner lumen is disposed within the heat transfer segments. The inner lumen is capable of transporting a pressurized working fluid to a distal end of the heat transfer element. The irregularities may be grooves, and the grooves have a curved termination point which directs blood along a direction having a component perpendicular to the axis of the segments, thereby enhancing turbulence and heat transfer.

Abstract: An electrosurgical instrument having a universal handle that is adapted for mounting and unmounting of different core assemblies for carrying out various electrosurgical procedures. The mounting and unmounting is accomplished by constructing the handle in several parts with upper concave portions configured to receive and hold the core assemblies which are provided with similar outer housings so they all can fit within the concave portions. The handle parts are held together with detent mechanisms which allow them to be easily snapped together and apart as desired. The handle can accommodate a variety of core assemblies that can comprise parts of a family of assemblies capable of both unipolar and bipolar electrosurgical procedures, and thus provides a very flexible instrument for the active surgeon.

Abstract: A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with an anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a secondary lead is surrounded by the primary leads, and extends beyond the primary leads.

Abstract: A therapeutic heat transfer pad includes a pad assembly having two sheets of impervious material connected or bonded to one another by an edge seal or seam along perimeters thereof to form a fluid receiving cavity therebetween. The sheets are also connected or bonded to one another by a plurality of inner seals or seams located interiorly of the edge seal to define a plurality of interconnected fluid passages. A pair of fluid inlet tubes extend into the fluid receiving cavity from externally of the pad assembly for introducing a heat transfer fluid into the fluid receiving cavity. The inlet tubes enter the fluid receiving cavity at a common entry point or location and terminate within the fluid receiving cavity at open ends, respectively. The open ends of the inlet tubes are spaced from one another in the fluid receiving cavity and are adjacent and in communication with different ones of the fluid passages.

Abstract: An electrosurgical handpiece that is bipolar or unipolar in operation and that is configured for use in MIS. The bipolar operation confines the electrosurgical currents to a small active region between the active ends of the bipolar electrode and thus reduces the possibility that excessive heat will be developed that can damage patient tissue. The position of the active region can be controlled to avoid patient tissue that may be more sensitive to excessive heat. In one embodiment, the handpiece is constructed with a flexible end controllable by the surgeon so as to allow the surgeon to manipulate the end as desired during the surgical procedure. This feature allows the surgeon to position the active electrode end at the optimum location within, say, a herniated disk to remove undesired regions and to provide controlled heat to shrink the tissue during surgery.

Abstract: In a sterilization method a plethora of magnetizable metal particles are deposited into a uterus of a living female organism. Subsequently, a magnet is placed near an external skin surface of the female organism near the uterus to thereby cause at least some of the metal particles to embed in a myometrium or endometrium of the uterus. The metal particles may be magnetized prior to deposition in the uterus. The particles are advantageously formed to have a sharp end which easily penetrates into the uterine lining. Each particle is magnetized so that the sharp end has a predetermined magnetic pole, whereby a magnet with the opposite pole placed against the organism results in an embedding of the sharp end in the uterine lining. In addition, microwave radiation is optionally transmitted into the female organism in a region about the uterus after the embedding of the metal particles in the myometrium or endometrium.

Abstract: A method and apparatus for performing hypothermia of a selected organ without significant effect on surrounding organs or other tissues. A flexible coaxial catheter is inserted through the vascular system of a patient to place the distal tip of the catheter in an artery feeding the selected organ. A chilled perfluorocarbon fluid is pumped through an insulated inner supply conduit of the catheter to cool a flexible bellows shaped heat transfer element in the distal tip of the catheter. The heat transfer bellows cools the blood flowing through the artery, to cool the selected organ, distal to the tip of the catheter.

Abstract: The present invention is a method and apparatus for conveniently and removably sealing inlet ports within an inflatable thermal blanket. In accordance with the present invention a generally planar sheet of material having a plurality of resilient side extensions extending from a central body is used to close an inlet port within an inflatable thermal blanket. In accordance with the preferred invention, the generally circular portion of the central body has a diameter which is slightly smaller than the diameter of the inlet port. Preferably, for extensions extend from the central body each extension being generally circular. Each extension is preferably formed from the same material used to form the central body, and is sufficiently resilient to be easily flexed and to return to an essentially coplanar sheet when released.

Abstract: The present invention involves a selective organ heat transfer device having a flexible coaxial catheter capable of insertion into a selected feeding artery in the vascular system of a patient. A heat transfer element is attached to a distal portion of the catheter as well as a turbulence-enhancing element which is adapted to enhance turbulent blood flow along the heat transfer element. The heat transfer element may include the turbulence-enhancing element and/or a turbulence-enhancing element may be located proximal of the heat transfer element.

Abstract: An bipolar electrosurgical tool (10) for cauterizing or ablating tissue. The tool has a nose cone (12) which serves as a handle. A conductive shaft (14) extends from the nose cone. A tip assembly (18) with an active electrode (20) is mounted to the shaft. A circuit board (78) is mounted in the nose cone. Conductive traces that forming contact pads (96, 102) are formed on the circuit board. A web (108) formed from a single piece of elastomeric material is seated over the opening in which the printed circuit board is mounted to seal the opening shut. Integrally formed with the web are buttons (116, 118) that are in registration over the contact pads. The buttons can be depressed downwardly towards the contact pads. When a button is so depressed, a conductive landing pad (120) integral with the button closes the connection between the traces that form the contact pad. Thus, the tool of this invention is provided with switches. The circuit board also has two conductive traces (92, 104a) that run in parallel.

Abstract: A method and apparatus for selective photothermolysis of a target tissue within surrounding tissue. The target and the surrounding tissue are heated to a predetermined temperature of about 60° C. by a pulsed heat source such as a flash lamp which creates a temperature gradient in the air included in a cavity formed between the housing of the apparatus and the surrounding tissue. The surface temperature of the tissue is monitored by a sensor unit. When the tissue surface reaches the predetermined temperature the target tissue is heated to the point of coagulation, preferably by narrow band electromagnetic radiation. The temperature difference between the coagulating target and the surrounding tissue is sufficiently mild that heat diffusing out of the target does not damage the surrounding tissue, even in the case of a relatively large target such as varicose veins.

Abstract: A thermotherapy device for treatment of diseased biological tissues. The thermotherapy device includes a primary and at least one secondary cooling and/or radiation shielding lumen. The lumens are connected or disposed adjacent one another along their longitudinal exterior walls. An energy source is insertable into one or more of the cooling lumens to carry out a heating protocol to treat the diseased tissue while screening and/or cooling normal tissue. A transrectal ultrasound positioning and temperature sensing device can control the energy source for effective treatment.

Abstract: Disclosed is a surgical apparatus including a surgical instrument including a housing and a cannula, and a surgical tool including a shaft and a tip, and a drive interface and an electrical interface, and the drive interface producing a surgical motion of the tip, and the electrical interface producing a cauterizing action of the tip. Also disclosed is a cutting and cauterizing device for connection to a surgical instrument. Additionally, methods for using both the surgical apparatus and the cutting and cauterizing device are disclosed.

Abstract: An electrosurgical handpiece that is bipolar in operation and that is configured for use in minimally invasive surgery (MIS). The bipolar operation confines the electrosurgical currents to a small active region between the active ends of the bipolar electrode and thus reduces the possibility that excessive heat will be developed that can damage patient tissue. The position of the active region can be controlled to avoid patient tissue that may be more sensitive to excessive heat. In one embodiment, the electrosurgical electrode ends are configured as parallel prongs spaced apart to embrace a blood vessel. In another embodiment, the electrosurgical electrode ends are configured as one straight and one hooked prong to more easily embrace a blood vessel. The handpiece is constructed with a flexible end controllable by the surgeon so as to allow the surgeon to manipulate the end as desired during the surgical procedure.

Abstract: A thermal and moisture barrier device for use with a specialized heating and humidifying apparatus in the care of extremely premature neonatal infants. The thermal and moisture barrier comprises a collapsible and substantially flexible cover which defines an enclosed volume, large enough to accommodate an extremely premature neonatal infant. At least one flexible opening is located on a portion of the cover which communicates with the enclosed volume. A diaphragm provides closure of the flexible openings. The diaphragm is a resiliently flexible sheet extending across the opening and has slits.