Patents Examined by Raymond Kenley, III
  • Inhibition of nitric oxide production by retinoic acid
    Patent number: 5457129
    Abstract: A novel method of inhibiting production of two important mediators of cellular function, tumor necrosis factor and nitric oxide, and treating a pathophysiological state characterized by an undesirable production or level of tumor necrosis factor or nitric acid. The methods of the present invention employ retinoic acid compounds. The most preferred retinoic acid is all-trans-retinoic acid.
    Type: Grant
    Filed: May 17, 1993
    Date of Patent: October 10, 1995
    Assignee: Research Development Foundation
    Inventors: Bharat B. Aggarwal, Kapil Mehta