Patents Examined by Ronald Griffin
  • Method of preparing etoposide
    Patent number: 5463040
    Abstract: The present invention relates to a method of increasing the yield of etoposide produced relative to prior art processes. A residue obtained as a result of reacting etoposide triacetate with a first lower alkanol in the presence of a first transesterification catalyst is provided. This residue is then reacted with a second lower alkanol and a second transesterification catalyst.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: October 31, 1995
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventor: Calvin Vogel
  • Inclusion compound of eicosapentaenoic acid and food product containing the same
    Patent number: 4831022
    Abstract: A novel EPA/CD inclusion compound and a food product containing the same are disclosed. The undesirable odor of EPA is masked by including it into such EPA/CD inclusion compound. Gamma-CD is most favorable because it includes much more EPA, and highly stabilizes it. The EPA/CD inclusion compound is advantageously usable in perorally- or parenterally-usable products directed to the promotion or maintenance of health.
    Type: Grant
    Filed: September 15, 1988
    Date of Patent: May 16, 1989
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Hiromi Hijiya, Masakazu Mitsuhashi, Toshi Miyake