Abstract: An intraparenchymal infusion catheter system for delivering drugs or other agents to selected sites in an organism, such as a human, includes a pump that may be implanted or disposed outside the organism. A catheter is coupled to the pump. The catheter comprises a flexible biocompatible tubular portion terminating in a free distal end. The distal end of the catheter bears a rounded tip, a portion of which is slidably disposed within the lumen of the tubular portion. The tip is porous for discharging an agent or drug to a selected site. The tip has a microporosity of less than or equal to 0.22 microns. The tubular portion is composed from a material that will expand from its nominal size when exposed to a stimulus such as heat or a solvent and return to its nominal size when the stimulus is withdrawn. By expanding the tubular portion, a physician can select the amount of the tip that is exposed to the organism, thereby customizing the catheter to the structural size of the selected site within the body.

Abstract: The present invention relates to a multiple valve single port manifold for use with a multiple lumen catheter. The inventive manifolds comprise a conduit with an entry port; a plurality of means for connecting the conduit to a plurality of catheter lumens, such that each lumen is capable of being in fluid communication with the entry port; and a plurality of means for controlling access from the conduit to the plurality of catheter lumens, such that each controlling means independently regulates access from the conduit to its corresponding catheter lumen. Because each catheter lumen is independently accessible from the same manifold port, the inventive devices are useful in any medical context where a need exists to independently control access to spatially proximal sites within a patient's passageway.

Abstract: Control apparatus for an ultrasonic phacoemulsification handpiece utilizes flow rates and temperature measurements as well as power provided to a handpiece for calculating an energy balance over a time interval and in response thereto, regulating power and/or fluid flow to and from the handpiece.

Abstract: An apparatus for altering characteristics of a fluid. The apparatus includes a first perimeter wall defining an internal chamber therein. The first perimeter wall defines a first opening and a second opening therethrough. The first opening is constructed to be fluidly connected to a fluid source. The internal chamber defined in said first perimeter wall is constructed to contain a beneficial agent therein. A beneficial agent is disposed in the internal chamber defined in the first perimeter wall, the beneficial agent being dispersible in a fluid flowing from the first opening to the second opening through the internal chamber defined in the first perimeter wall.

Abstract: An improved single- or multiple-dose syringe having a conventional housing and an improved plunger configuration carrying a medicament- or saline-filled cartridge the contents of which are sequentially dispensed after the dispensing of a volume of a drawn-up primary fluid. A method for sequential administration of medicinal fluids using the improved syringe is also a part of the invention.

Abstract: An intravenous (IV) fluid heat exchanger which transfers heat from a heating medium to an intravenous fluid being delivered to a patient. The IV fluid heat exchanger includes an input manifold for receiving the IV fluid and distributing the IV fluid through a plurality of passageways extending from the input manifold. An output manifold is also provided for receiving the IV fluid flowing through the passageways and directing the IV fluid through an exit path out of the IV fluid heat exchanger. The passageways are positioned in the proximity of the heating medium, wherein the passageways facilitate the transfer of heat from the heating medium to the IV fluid passing through the passageways. By providing a plurality of passageways for the IV fluid, the surface area of the IV fluid exposed to the inner surfaces of the heated passageways is optimized to improve the heating efficiency of the IV fluid heat exchanger.

Abstract: A plastic pre-filled syringe which includes an open ended barrel sealed at one end by a moveable stopper and sealed at the other end by a closure frangibly connected to the syringe. The syringe also includes an overcap which can be moved so to engage with the closure whereby removal of the overcap will cause the closure to be separated from the rest of the syringe and reveal the contents for injection.

Abstract: The present invention relates to a system for irrigating a wound with wound irrigation fluid and for preventing substantial splashback of the wound irrigation fluid. The system comprises: (i) fluid delivery device for delivering wound irrigation fluid; and (ii) a flexible wound irrigation shield configured such that the shield prevents substantial splashback of the irrigation fluid upon irrigation of a wound. The shield is configured to be disposed, preferably removably, on the fluid delivery device. The flexible shield is substantially conformable to a desired wound area, enabling the practitioner to irrigate awkward, uneven, and hard to reach areas. The shield can be folded into a compact position, then opened into a larger shield. The fluid delivery device comprises (i) a fluid source for providing wound irrigation fluid; and (ii) an adaptor for transmitting fluid from the fluid source to the wound.

Abstract: An ear tube for ventilating and equalizing the pressure between a middle ear and an outer ear. The ear tube is comprised of a shaft and a tab. The shaft further includes a top and a bottom at opposite longitudinal ends of the shaft, and a lumen with a major dimension greater in length than a perpendicular minor dimension. The tab extends outward, perpendicular from the bottom of the shaft.

Abstract: A container for a sterile medical solution comprises an upper surface, a lower surface, and a rigid top border having a central portion and peripheral portions. At least one separation line joints the upper and lower surfaces of the container to form first and second compartments. The top border of the container includes lines of weakness in the central portion thereof to form a hinged connection between the peripheral portions of the top border so that solutions in the first and second compartments are more quickly mixed when openable connectors between the compartments are broken.

Abstract: Device for securing and, if appropriate, straightening the ends of catheter guide wires. The device has an elongate hollow element open at both ends, with a cylindrical section and a conical section which tapers towards one end. A U-shaped slit which extends in the longitudinal direction is present in the wall of the hollow element, so that a tongue which can be pressed into the inside of the hollow element is formed between the legs of the U-shaped slit which open towards the one end.

Abstract: An electronic surgical probe including an axially elongated member adapted to receive ultrasonic vibrations from an ultrasonic motor or transducer and having a circular cross-section, has a coaxially positioned cannula or sheath and outer layer of TEFLON surrounding the elongated member, the cannula or sheath defining an aperture adjacent the distal end portion of the elongated member, wherein fluid adjacent the distal end portion of the elongated member is activated or cavitated by ultrasonic vibrations from the distal end of the elongated member and passing through the aperture of the cannula acts upon tissue and/or other matter.

Abstract: A sleeve apparatus for a phacoemulsification/irrigation and aspiration handpiece having an ultrasonic drive assembly attached to a hollow needle includes a compressible sleeve for establishing an annular passage around the needle and enabling the irrigation fluid to pass into an eye through a cornea/sclera wound while cooling the needle. The compressible sleeve includes a wall configuration for controlling compression of the sleeve in order to cause the compressible sleeve to shape and conform to the corneal/sclera wound and limit fluid egress from the wound. A hub is provided for attaching the compressible sleeve to the handpiece and enabling the needle to be angularly displaced within the compressible sleeve means during phacoemulsification.

Abstract: There is disclosed a medical catheter comprising a proximal shaft section and a distal shaft section. The proximal shaft section has an inner diameter and wall thickness which is constant over the length of the proximal shaft section. The distal shaft section has an inner diameter which is greater than the proximal shaft inner diameter and has a step up or taper therebetween. The proximal end of the distal shaft section is aligned proximal to the proximal end of a curved portion of the guiding catheter's distal shaft section.

Abstract: A system for non-invasively withdrawing and monitoring bodily fluids from the skin of a user is provided. The system apparatus includes a portable hand-held housing (16) having an internal chamber (9). Fluid displacement mechanism (1) is removably coupled to the housing (16) for directing the fluid from the skin into the internal chamber (9). The fluid displacement mechanism (1) has a first end (20) adapted to be located on an outer surface of the skin and an opposing second end (21) located internal the housing (16). Vacuum pump (10) in the housing (16) non-invasively extracts the fluid from the skin and draws the extracted fluid into the internal chamber (9) through the fluid displacement mechanism (1). A monitoring mechanism within the internal chamber (9) monitors the fluid drawn into the chamber (9).

Abstract: A catheter includes a segment having a longitudinal axis. The segment has a helical coil extending coaxially with the longitudinal axis. The coil has a plurality of turns along a length of the axis. Adjacent turns have opposing surfaces joined by bridging members tying at least selected ones of the adjacent turns.

Abstract: The invention relates to a tampon applicator having a cylindrical outer sleeve and an inner sleeve, which is displaceable therein, is provided with an axial longitudinal slit and encloses a tampon. A tongue-shaped retention element is integrally connected to the outer sleeve so as to be bendable and projects through the longitudinal slit of the inner sleeve into the latter, and lies against the rear end of the tampon. When the inner sleeve is withdrawn out of the outer sleeve, the tampon is held in place by the retention element and transferred into the outer sleeve. The retention element is provided with one part of a locking mechanism (detent plate), the other part of which is formed by one of the two sleeves (longitudinal edges of the longitudinal slit of the inner sleeve. The aforesaid locking parts interact in such a way that the retention element is locked in its engaged position bent into the inner sleeve.

Abstract: A trocar assembly consisting of a trocar in a central opening in a cannula. The cannula is provided with at least one separate passage running parallel to the central passage. The separate passage is connected to a source of cleansing fluid and a pump for pumping fluid through the separate passage. The separate passage terminates in an orifice near the distal end of the central opening of the cannula. In operation, when the cannula is used to provide access for a laparoscope or other viewing instrument, the end of the viewing instrument may become clouded with moisture and other debris. In this case, the end of the viewing instrument may be withdrawn into the distal end of the cannula adjacent the fluid orifice. The pump is actuated and cleansing fluid is forced over the end of the instrument cleaning away the obstructing matter without removing the instrument from the cannula. Drying air can also be supplied to the instrument, either through the same or a different separate passage.

Abstract: A process for making a reinforced tubular product, especially a catheter, in a single extrusion step. A reinforcing member is applied to an extruded thermoplastic catheter body of about its finished size which is softened by heating while tensioning the reinforcing member to control the surface deformation or penetration of the catheter wall by the reinforcing member to produce an irregular surface contour on the catheter body. The catheter body is then smoothed in a sizing die burying the reinforcement to form the finished product. The heating step may be in addition to or substituted by a curing step when a thermosetting or cross-linking material is used for the body. The reinforcement may be braid, or a helical wrap of one or more members applied at one or more controlled angles relative to the axis of the catheter to control the apparent stiffness and torque transmission efficiency of the catheter.

Abstract: An expansible balloon catheter has at least a first exterior surface with a given coefficient of friction and a second exterior surface with a greater coefficient of friction. In a compact form only the first exterior surface is exposed to produce one coefficient of friction during transfer of the collapsed or uninflated balloon to and across a lesion. When inflated, the second surface dominates the first surface and produces a second coefficient of friction.