Abstract: Provided herein are, inter alia, compositions, systems, and methods for preventing or treating acne. Included are compositions, combinations, systems, and methods comprising at least one Propionibacterium acnes bacteriophage, at least one anti-acne compound, and a pharmaceutically acceptable carrier. Also included are compositions, combinations, and systems comprising a Propionibacterium acnes bacteriophage and an enzyme. Methods for preventing or treating acne are also provided.
Abstract: A composition and method for ameliorating drug-seeking behavior in drug addicts who have stopped using the addicted-to drug and who have reestablished non-addict physiological chemical balance.
Abstract: Provided herein are compositions and methods for the inhibition of enteric infection. In particular, compositions comprising bacteria of the class Clostridia are administered to human and/or animal subjects to prevent or decrease susceptibility to enteric infection.
Type:
Grant
Filed:
July 15, 2022
Date of Patent:
January 30, 2024
Assignee:
The University of Chicago
Inventors:
Cathyrn R. Nagler, Gabriel Nunez, Yun-Gi Kim
Abstract: The present invention relates to a built-in bio-sleeve and preparation method and use thereof. In order to provide a suitable built-in bio-sleeve material for dorsal nerve isolation surgery and penis enlargement surgery, a novel acellular allogeneic dermal matrix material is prepared in the present invention, which is manufactured into a built-in bio-sleeve for the treatment of premature ejaculation and short and small penis. The acellular allogeneic dermal matrix or the built-in bio-sleeve of the present invention is used for dorsal nerve isolation surgery, penis enlargement or lengthening surgery without cutting off the dorsal nerve, thereby avoiding the probability of psychological erectile dysfunction caused by the patient's worry about cutting off the dorsal nerve.
Abstract: The present invention provides improved methods, facilities and systems for parallel processing of biological cellular samples in an efficient and scalable manner. The invention enables parallel processing of biological cellular samples, such as patient samples, in a space and time efficient fashion. The methods, facilities and systems of the invention find particular utility in processing patient samples for use in cell therapy.
Abstract: Compositions and methods are provided in which a nutritional supplement that is utilized in the treatment viral infections (e.g., coronavirus, HCV, HIV), by correcting dysregulation of apoptosis, reducing production of pro-inflamatory cytokines, and increasing production of host anti-viral compounds. The nutritional supplements can be used in combination with known antiviral therapies, as well as low level radiotherapy and/or chemotherapy drugs conventionally used in the treatment of neoplastic disease.
Abstract: The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
Type:
Grant
Filed:
April 19, 2022
Date of Patent:
January 16, 2024
Assignee:
Korea University Research and Business Foundation
Inventors:
Kyoung Heon Kim, Yong-Su Jin, Eun-Ju Yun, Dong-Hyun Kim, Sora Yu, Kyung-Mun Cho, Na Jeong Park
Abstract: The present invention provides a coated-type feed additive composition for improving body weight gain of livestock or feed conversion ratio for livestock comprising: a core containing a physiologically active substance having a property of strengthening a membrane of intestinal epithelial cells; and a core coating agent.
Abstract: The present invention concerns a postbiotic composition comprising at least one postbiotic and at least one bacteriocin and/or endolysin, preferably formulated, and a postbiotic composition comprising at least one postbiotic and at least one bacteriocin and/or endolysin for use as a medicament, wherein said postbiotic is preferably a microbial lysate, preferably obtained from microorganisms heterologously expressing said at least one bacteriocin and/or endolysin and wherein said at least one postbiotic and said at least one bacteriocin and/or endolysin have a synergistic effect in the therapeutic treatment.
Abstract: The subject invention provides compositions and methods for inhibiting viral infections. Preferred embodiments of the invention provide pharmaceutical compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof.
Type:
Grant
Filed:
June 7, 2021
Date of Patent:
November 28, 2023
Assignee:
QUORUM INNOVATIONS, LLC
Inventors:
Nicholas T. Monsul, Eva A. Berkes, Frederick T. Boehm, Yu-Hsien Liao
Abstract: The invention provides an enzymatic method for measuring the concentration of one or more analytes in the plasma portion of a blood derived sample, containing a first and a second component, where said second component interferes with the measurement of said first component.
Type:
Grant
Filed:
June 30, 2021
Date of Patent:
November 14, 2023
Assignee:
ABBOTT RAPID DIAGNOSTICS INTERNATIONAL UNLIMITED COMPANY
Inventors:
Arne Ludvig Faaren, Frank Frantzen, Arne Kristian Nordhei, Erling Sundrehagen, Lars Ørning
Abstract: The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.
Type:
Grant
Filed:
February 8, 2021
Date of Patent:
November 14, 2023
Assignee:
DUKE UNIVERSITY
Inventors:
Joanne Kurtzberg, Geraldine Dawson, Jesse Troy, Jessica Sun
Abstract: The present invention relates to compositions comprising one or more extracts and/or compounds having retinol-like activity and properties and methods of using the compositions to treat the eye.
Abstract: Methods of preparing placental tissue products/compositions are disclosed together with methods of utilizing the placental tissue composition for delivery of a therapeutic agent.
Abstract: This disclosure relates to pharmaceutical compositions for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold. The pharmaceutical composition can comprise a probiotic formulation of non-pathogenic bacteria, vitamin C and vitamin D along with a pharmaceutically acceptable excipient or filler. A method of for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold is also disclosed in which a patient in need of a treatment for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold is identified. The pharmaceutical composition can then be administered orally to the patient.
Abstract: The present invention relates to methods of modulating dermal and sub-dermal properties of a subject. The present invention relates to methods comprising administering to a subject a spore-based probiotic composition.
Type:
Grant
Filed:
September 7, 2021
Date of Patent:
October 17, 2023
Assignee:
Novozymes A/S
Inventors:
Kiran Krishnan, Dale M. Kriz, Thomas F. Bayne
Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
Type:
Grant
Filed:
October 26, 2020
Date of Patent:
October 10, 2023
Assignee:
RTI Surgical, Inc.
Inventors:
C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
Abstract: Micronutrient compositions for treating hair loss, and methods for treating hair loss by periodically administering the compositions. The micronutrients include vitamins, antioxidants, minerals, such as ferrous, calcium, and zinc salts, amino acids, fatty acids, co-enzyme Q10, biotin, omega 3, B-complex, curcumin, colostrum, lactoferrin, N acetyl cysteine, inositol, melatonin, biotin, and the like, and combinations thereof. Careful selection of doses and dosing schedules allows enhancing efficiency, preventing antagonism, reducing side effect and avoiding wastage and overdose of the micronutrients. The components support the activity of the hair growth cycle, and act as building blocks required for hair growth, lack of which can lead to slowing down and arrest of hair growth. They also help maintain inter- and intra-cellular calcium levels, reduce interference with glucose metabolism, gastric irritation and constipation in patients, and promote hair growth, without using Minoxidil or Finasteride.
Abstract: The present invention provides a method and a dietary composition for prevention and regulation of obesity capable of obtaining efficacy such as required appetite suppression or satiety by having a positive effect on concentrations of neurotransmitters such as serotonin, dopamine, and norepinephrine, and GLP-1 which are the principle of a mechanism of appetite inhibitory drugs without prescription of medicines (Phentermine, Prozac, Saxenda, etc.) and further being used as an alternative diet and supplying a protein that is the most lack ingredient during diet. The dietary composition includes tryptophan, which is one amino acid, tyrosine, which is the other amino acid, arginine, which is another amino acid, and a whey protein as active ingredients.
Abstract: The present application relates to a Bifidobacterium breve or progeny thereof. Specifically, the present application relates to Bifidobacterium breve 207-1 and a composition, culture, food product or dietary supplement containing the same. The present application also relates to the use of Bifidobacterium breve 207-1 and the composition, culture, food product or dietary supplement containing the same in medicine.
Type:
Grant
Filed:
February 2, 2021
Date of Patent:
September 26, 2023
Assignee:
BYHEALTH CO., LTD.
Inventors:
Xiaolei Ze, Xuguang Zhang, Ruikun He, Fang He