Abstract: A suture securing system is provided for use in closing a vessel puncture site while eliminating the need for sutures to be manually tied in knots. The system may include an elongate body comprising a shaft and a barrel slidably mounted on the shaft. A knot replacement element may include an outer surface and an inner lumen configured to receive suture lengths. The knot replacement element may be at least partially positioned within the distal end of the barrel adjacent to the distal portion of the shaft and may be configured to selectively fasten the suture lengths together over the vessel repair site. The system may also include a snare configured to draw the suture lengths through the knot replacement element and at least a portion of the elongate body. A trimmer member may be configured to selectively trim the suture lengths extending from the knot replacement element.

Abstract: An expandable mechanical distension device for hollow organ growth comprising a spring stent structure to elongate hollow organs by mechanical expansion. The device preferably expands radially to engage the internal walls of the hollow organ segment at a desired treatment location and expands axially to enlarge the hollow organ segment. The distension device may be configured for the treatment of patients with insufficient hollow viscus, e.g. hollow organ deficiency such as short gut syndrome, to enhance their gut length by mechanical force.

Abstract: Suture anchors are disclosed having suture locking features able to lock multiple suture ends extending from a body tissue, such as from a bone tunnel, with a single device.

Abstract: In various embodiments, a device for treating disease of a vessel includes a stent graft having an outer surface; and at least two side branch portals each having a proximal end and a distal end. Each distal end is substantially contiguous with the outer surface of the stent graft. In various other embodiments, the distal ends are generally axially further spaced apart than the proximal ends.

Abstract: A shaped medical balloon is provided that has a conforming shape, yet is inexpensive to manufacture, wherein a central portion of the balloon is folded inside and welded together at the fold and is further welded to said lumen, thus creating a conforming depression in the surface of said balloon at the central portion.

Abstract: An atherectomy device is disclosed, which is rotationally driven by an electric motor. In some designs, the device includes features unavailable on gas turbine-driven systems, such as the storing in memory of low/medium/high preset rotation speeds for particular models of handle, calculations of the amount of saline left in the IV and associated warnings when it gets sufficiently low, and automatic adjustment of the IV pump rate to a predetermined or calculated level when the rotational speed of the motor is changed. The electric motor has far more rotational inertia than a comparable gas turbine, so the system includes a control mechanism that helps prevent damage from excessive torque being applied to the distal end of the drive shaft. When an obstruction at the distal end is detected, by a drop in the motor rotational speed, the motor is released and is allowed to spin freely as a flywheel.

Abstract: An atherectomy device is disclosed, which is rotationally driven by an electric motor. In some designs, the device includes features unavailable on gas turbine-driven systems, such as the storing in memory of low/medium/high preset rotation speeds for particular models of handle, calculations of the amount of saline left in the IV and associated warnings when it gets sufficiently low, and automatic adjustment of the IV pump rate to a predetermined or calculated level when the rotational speed of the motor is changed. The electric motor has far more rotational inertia than a comparable gas turbine, so the system includes a control mechanism that helps prevent damage from excessive torque being applied to the distal end of the drive shaft. When an obstruction at the distal end is detected, by a drop in the motor rotational speed, the motor is released and is allowed to spin freely as a flywheel.

Abstract: A surgical instrument may include an end effector, an input drive shaft, a closure drive, and/or a firing drive. The end effector may comprise a jaw assembly including a first jaw member and a second jaw member. The end effector may comprise an I-beam member axially translated between a proximal position and a distal position within the end effector. In one embodiment, the input drive shaft may selectively engage the firing drive and/or the closure drive. In one configuration, the closure drive is threadedly engaged with the firing drive allowing the input drive shaft, during a firing stroke, to simultaneously move the closure drive and the firing drive until the closure drive is disengaged from the firing drive. On a reverse stroke, the closure drive may be reengaged with the firing drive.

Abstract: A mesh patch for a laparoscopic hernia surgery, which includes a flexible mesh, an adhesion layer surface, and an anti-adhesion layer surface. The flexible mesh is formed of a thin layer of filament using a biocompatible polymer. The adhesion layer surface is disposed on a front surface of the mesh. The adhesion layer surface is coated with an adhesion inducing material to be fixedly attached to a peritoneum. The anti-adhesion layer surface is disposed on a rear surface of the mesh. The anti-adhesion layer surface is coated with an anti-adhesion material so as not to adhere to intestines in an abdominal cavity. The protection film is detachably attached to the adhesion layer surface and the anti-adhesion layer surface to protect the mesh. Here, the protection film is easily detached by a laparoscopic instrument, and has an adhesive strength such that the mesh is unfolded upon detaching.

Abstract: A device and method for marking a treatment isocenter on a patient's body. One embodiment includes a base including alignment indicia, a marker disposed over the base and positioned relative to the indicia for marking the isocenter on the patient's body and an actuator for actuating the marker and causing a mark indicating the isocenter to be made on the patient's body. The actuator can include a button and a spring coupled to the marker. Compressing the actuator causes the marker to travel through an ink well prior to piercing the patient's skin.

Abstract: A surgical tissue cutting instrument comprises a tubular outer member, an inner member rotatably disposed within the outer member and having a cutting element, a handpiece, and an irrigation system. The irrigation system includes an irrigation channel composed of a first irrigation passage within the handpiece and a second irrigation passage within the thickness of the annular wall of the outer member, and a sleeve disposed over a front end of the handpiece and over the outer member adjacent an outlet opening of the second irrigation passage. The sleeve allows communication through the outlet opening of the second irrigation passage and an inlet port of the first passage. The inlet port is connectible with a source of irrigation fluid.

Abstract: A system for treating a patient is provided that includes an expandable vascular device having a body having a substantially uniform porosity that is adapted to change by adjusting an axial length of the body. The system also includes an expanding member positioned within a central lumen of the device, the expanding member configured to engage the body, as the body is radially expanded from a collapsed configuration, and to reduce a porosity of the body within a body region more than the body porosity is reduced outside the region.

Abstract: In one general aspect, various embodiments are directed to an ultrasonic surgical instrument that has an ultrasonic blade that protrudes from an ultrasonic transducer assembly. In some embodiments, the ultrasonic blade coaxially extends through a rotatable tissue cutting blade that is rotatably supported by a housing that supports the ultrasonic transducer assembly. In other embodiments, the ultrasonic blade and the tissue cutting blade are both selectively rotatable relative to the housing. In yet other embodiments, the tissue cutting blade and the ultrasonic blade are supported relative to each other in separate sheaths attached to the housing.

Abstract: A surgical instrument comprises a handle having a blade proximate a distal end of the handle. A blade edge inset from a mouth of the recess is exposed within the recess and faces at least partially toward a proximal end of the handle with the blade edge inset from a mouth of the recess. The distal end further comprises a point bounding a portion of the recess and facing at least partially toward the proximal end of the handle. Methods of use are also disclosed.

Abstract: The present invention relates to methods of using medical cutting tools for treating aortic septal dissections.

Abstract: A vascular closure device includes a carrier tube, a sealing tip, and a sealing tip connection member. The carrier tube includes a distal end. The sealing tip is releasably connected to the distal end of the carrier tube. The sealing tip connection member extends through the sealing tip and includes a proximal portion extending proximally from the sealing tip. Applying a tension force at the proximal portion of the sealing tip connection member removes the sealing tip connection member from the sealing tip, and removing the sealing tip connection member from the sealing tip radially expands a portion of the sealing tip.

Abstract: Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes various example vitrectomy probes having an adjustable cutting port size. For example, one example vitrectomy probe includes a piezoelectric element adapted to adjust the size of the cutting port. Further, the disclosure provides examples for adjusting the size of the cutter port while the vitrectomy probe is in operation.

Abstract: A medical retrieval basket used for entrapping and extracting objects such as urinary and biliary calculi from the body comprising a handle assembly, a flexible shaft, and a basket. The basket comprises a plurality of outwardly disposed shape memory wires and is bulbous in shape at its distal end. Located at the intersection point of the wires at the distal end of the basket is a hub that restricts the degree of relative movement between the wires. This hub also serves to increase contact points with the object to be retrieved and to stabilize the orientation of the basket wires. The substantially tipless configuration of the distal end of the basket permits the basket to retrieve objects from difficult to reach locations and reduces tissue trauma caused by the basket tip. The basket wires have varying cross sectional shapes and sizes in different sections of the basket to optimize the performance to the needs of each section within the basket.

Abstract: Vitrectomy probes and system related thereto are disclosed herein. The disclosure describes vitrectomy probes having an adjustable cutting port size. In some instances, the cutting port size may be adjusted by altering a position of a stroke limiter via a pancake motor. Various example features are described for adjusting the size of the cutting port.

Abstract: A stent deployment device and methods for use, where the device comprises: (a) an outer sheath having a proximal end and a distal end, (b) a pull apparatus at least partially disposed within the outer sheath, where a portion of the pull apparatus is sized and shaped to receive a stent or a stent graft, (c) a push apparatus, where a portion of the push apparatus is sized to fit within a portion of the pull apparatus, and (d) a push-pull drive mechanism in mechanical communication with the pull and push apparatuses, where the push-pull drive mechanism includes at least a push and a pull gear or a push and a pull reel sized and shaped based on a stent ratio.