Patents Examined by Samuel Siefke
  • Patent number: 7247496
    Abstract: The measurement of the particle size distribution of an aerosol is of crucial importance in pharmaceutical development. A prerequisite for this is a valid method, e.g. the cascade impactor method described in the pharmacopoeias. It requires measurement of the active substance concentration in order to determine the particle size distribution. The invention provides a process which makes it possible to measure the size of aerosol droplets containing pharmaceutical substances which are unstable in the event of changes in the pH.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: July 24, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Dieter Hochrainer, Georg Boeck, Hubert Hoelz, Christian Scheffler, Christoph Kreher
  • Patent number: 6682937
    Abstract: Methods are provided for glucose detection and quantification in urine. The methods include selecting a test device comprising a matrix impregnated with a chromogenic indicator mixture, locating the test device to promote incidental contact of same with animal urine, reading a developed indicator color after the device has been wetted with urine, and determining the animal's urine glucose concentration.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: January 27, 2004
    Assignees: Hach Company, Nestec, Ltd.
    Inventors: Vladimir Evtodienko, Iouri Evtodienko, Lydia Dobler, Michael A. Van Lente, Ronald A. Lewis, II
  • Patent number: 6627450
    Abstract: Methods of measuring free and total chlorine content in solutions are provided without lowering the pH of the solution to the acid range by modifying a solution containing chlorine and water to contain a proton donating compound and electrochemically measuring the concentration of the chlorine in the solution. An additional potassium iodide reagent is added when total chlorine content is measured. Stable aqueous reagent solutions useful in automated chlorine analyzers which contain sodium bicarbonate, a base, and water or borax, water, and acid are also described. Finally, apparatuses for detecting the level of chlorine in water samples utilizing an automated chlorine detector, a cartridge having a solid proton donating compound, and optionally a standpipe are discussed.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: September 30, 2003
    Assignee: Severn Trent Water Purifications, Inc.
    Inventors: Robert M. Taylor, Dianne M. Phelan
  • Patent number: 6531322
    Abstract: A visual blood glucose test strip has two membranes that each incorporate a reagent that reacts with glucose in a blood sample applied to the membranes to cause a color change. One of the membranes also includes an inhibitor and a dye. A blood sample applied to the strip causes the two membranes to form two different colors. Comparing the colors to a calibrated color chart permits a user to determine the glucose concentration in the blood sample.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: March 11, 2003
    Assignee: Lifescan, Inc.
    Inventors: Franklin A. Jurik, Andrea Stubbs, Mimi Diemmy Dao, Carol Chang
  • Patent number: 6444169
    Abstract: Devices and test kits are provided for glucose detection and quantification in urine. The devices and kits comprise a chromogenic indicator mixture comprising a first indicator capable of color development to indicate the presence of a low-to-medium concentration of glucose, a second indicator capable of color development to indicate the presence of a higher concentration of glucose, wherein the first indicator prevents color development of the second indicator unless the higher concentration of glucose is present in the urine, and a non-chromogenic scavenger that interferes with color development of the first indicator when glucose levels are below a threshold concentration, and a carrier impregnated with the chromogenic indicator mixture.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: September 3, 2002
    Assignees: Ralston Purina Company, Environmental Test Systems, Inc.
    Inventors: Vladimir Evtodienko, Iouri Evtodienko, Lydia Dobler, Michael A. Van Lente, Ronald A. Lewis, II