Abstract: Apparatus(es)/method(s) relating generally to remotely administering a medication is/are disclosed. In one such method, a drug delivery device is obtained. The drug delivery device has: at least one reservoir in fluid communication with a needle; at least one actuator to drive a fluid within a respective at least one reservoir to the needle; a microcontroller to control operation of the at least one actuator; and a dosage control loop configured for communication with the microcontroller and a hemoglobin sensor. A dosage provided by the drug delivery device is automatically adjusted responsive to hemoglobin count sensed by the hemoglobin sensor for transdermal administration of medication for management of chronic kidney disease.

Abstract: A suction and irrigation implement includes a handpiece, a pair of aligned adjacent valve assemblies, a rocker and a hub. The body may be transparent to allow visualization of aspirated substances. The valve assemblies include a plunger with a conical core that increases the area of the valve opening with increased depression. The rocker, a pivoting actuator, opens one valve assembly at a time, thereby preventing simultaneous irrigation and suction. A suction and irrigation tube connects to the hub, which may be rotated to adjust the orientation of the tube, while the implement is in use. Detents define specific orientations.

Abstract: A priming system including a resilient chamber having flexible walls and a first check valve in a first fluid pathway between the resilient chamber and a fluid reservoir such that a fluid flows through the first check valve only in a direction from the fluid reservoir toward the resilient chamber and the fluid returns to the fluid reservoir through a second fluid pathway between the resilient chamber and the fluid reservoir upon compression of the walls of the resilient chamber.

Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.

Abstract: Aspiration systems and methods for controlling blood loss during thrombus removal are disclosed herein. The systems include an aspiration catheter, an aspiration tubing, a receptacle for collecting aspirated blood, a vacuum line coupled to the receptacle, and a sensor configured to measure a flow parameter associated with a liquid within an aspiration lumen. The systems further include a regulator configured to adjust a vacuum pressure within the vacuum line, and a vacuum controller operably coupled to the sensor and the regulator. The vacuum controller is configured to receive the flow parameter from the sensor, compare the flow parameter to a target range for the flow parameter, and send an automatic control signal to the regulator based on a comparison of the flow parameter to the target range. The automatic control signal causes the regulator to adjust the vacuum pressure within the vacuum line.

Abstract: An irrigation system having attachable anti-sliding features that prevent movement of the system along a surface. The irrigation system includes a console having a front panel with an inflow pump and an outflow pump. The front panel extends to a front edge of the console and the front edge is connected to a bottom side of the console. The attachable anti-sliding features include one or more feet attached to the bottom side of the console. Each foot has an L-shaped body having a first end and a second end with a first surface and an opposing second surface both extending between the first end and the second end. A protrusion extends from the second end of the body, forming the L-shape. The one or more feet are attached to the bottom side of the console such that the protrusion extends away from the console.

Abstract: Described is an actuation mechanism for a medicament delivery device having a needle with a distal tip. The actuation mechanism comprises an outer sleeve telescopically relative to the delivery device and an inner sleeve telescopically arranged relative to the outer sleeve. The outer sleeve is axially translatable relative to the delivery device, and the inner sleeve is axially translatable relative to the outer sleeve. In a first state, the inner sleeve protrudes distally from the outer sleeve and the outer sleeve protrudes distally from the delivery device. In a second state, the inner sleeve is contained within the outer sleeve. Movement of the outer sleeve proximally relative to the delivery device in the second state initiates delivery of a medicament in the delivery device.

Abstract: The present invention provides a coronary artery bypass surgery treatment tool or the like including a flexible tube, a suction cup in which an opening portion is formed to communicate with the flexible tube and which is provided at a distal end of the flexible tube, a joint portion which has a suction path, a male connector which is provided in one of a proximal end of the flexible tube and a distal end of the suction path of the joint portion, and a female connector which is provided in the other thereof and is detachably connected to the male connector.

Abstract: A phacoemulsification surgical console, and a related system and method. The console, system and method may include a cassette receiver suitable for receiving a surgical cassette, a controller suitable for controlling provided aspects of the phacoemulsification; and a pre-alignment feature along a lower portion under and proximate to the cassette receiver, extending outwardly from the lower portion, and suitable for aligning the surgical cassette to the cassette receiver. The pre-alignment feature may comprise a shelf.

Abstract: The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002? to about 0.008?.

Abstract: An electronic automatic injection device including a housing configured to receive an injection module containing a material to be injected, an electric motor having a rotary drive output, at least one forward driving spring and a multifunctional electric motor driven drive assembly responsive to the rotary drive output of the electric motor and being operative in a first mode of operation, when the injection module includes a prefilled syringe, to enable the at least one forward driving spring to displace the prefilled syringe in a forward direction and in a second mode of operation, when the injection module includes a needleless cartridge, to eject the injectable liquid from the prefilled syringe through a needle.

Abstract: Devices and methods are disclosed for improved irrigation sleeves for ophthalmic instruments to prevent or reduce the likelihood of the irrigation sleeve twisting and/or buckling upon inserting the irrigation sleeve into the eye. In some embodiments, an irrigation sleeve comprises a side opening for irrigation having an elongated shape, wherein the elongated shape is longer in a direction parallel to the longitudinal axis of the distal tube of the irrigation sleeve than in a direction around a circumference of the distal tube of the irrigation sleeve. In some embodiments, an irrigation sleeve comprises at least one rib on an internal surface of the distal end of the irrigation sleeve. In some embodiments, the irrigation sleeve has been subjected to one or more manufacturing steps adapted to stiffen the irrigation sleeve, such as being coated with a stiffening coating or being treated by being exposed to gamma irradiation.

Abstract: A method of managing insulin includes receiving blood glucose measurements on a computing device from a glucometer. The blood glucose measurements are separated by a time interval. The method includes determining, by the computing device, an insulin dose rate based on the blood glucose measurements and determining a blood glucose drop rate based on the blood glucose measurements and the time interval. The method also includes determining a blood glucose percentage drop based on the blood glucose measurements. The method includes decreasing the time interval between blood glucose measurements by the glucometer when the blood glucose drop rate is greater than a threshold drop rate, and decreasing the time interval between blood glucose measurements by the glucometer when the blood glucose percentage drop is greater than a threshold percentage drop.

Abstract: A breast pumping assembly for a forward-leaning chair is provided. The assembly allows for a breast pumping mother to be optimally positioned and comfortable while pumping breast milk, leading to quicker and more effective pumping. The breast pumping assembly and the chair are adjustable to adapt for different sized mothers and changing body size and shape as pumping progresses.

Abstract: Some embodiments of a medical device anchor system include an anchor device that receives a medical instrument (such as a catheter or the like) and secures the instrument in place relative to a skin penetration point. In some circumstances, the anchor device may allow the anchor device to be used after medical instrument is already in place without the need for a second penetration point for the anchor device.

Abstract: The device includes a dilator having a valve element configured to at least inhibit fluid flow through the dilator in a distal direction, while not inhibiting the passage of articles (e.g., a guidewire) through the dilator in a proximal direction.

Abstract: The present invention provides a coronary artery bypass surgery treatment tool or the like including a flexible tube, a suction cup in which an opening portion is formed to communicate with the flexible tube and which is provided at a distal end of the flexible tube, a joint portion which has a suction path, a male connector which is provided in one of a proximal end of the flexible tube and a distal end of the suction path of the joint portion, and a female connector which is provided in the other thereof and is detachably connected to the male connector.

Abstract: A balloon catheter is disclosed which allows easier fusion-bonding between an inner tube shaft and an outer tube shaft and in which the inner tube shaft can be prevented from being warped when the inner tube shaft passes through a stenosed site, and a method of manufacturing such a balloon catheter. The balloon catheter includes an inner tube shaft having a first layer and a second layer located on an inner surface side of the first layer. The outer tube shaft is fusion-bonded to the first layer and recessed toward the inner tube shaft side. The first layer is formed of a material having higher optical absorption property than the outer tube shaft and the second layer. The second layer is formed of a material having a melting point higher than that of the first layer.

Abstract: An autoinjector for dispensing a fluid product, in particular a medicament, comprises: a) a housing (2) and a product container (13), in particular a syringe, arranged in the housing and has a piston displaceable in a distal direction, by means of an advancement member, in order to dispense the product contained in the product container, b) a removable covering cap (4) arranged at the distal end of the housing, c) a triggering member (3), which, in the starting position, projects beyond the distal end of the housing, d) where the triggering member, in order to trigger the dispensing operation, can move in a proximal direction relative to the housing from the starting position into a triggering position when the covering cap has been removed from the housing, and e) where the triggering member is blocked against movement into the triggering position when the covering cap is arranged on the housing.

Abstract: Improved devices and methods for the expression of milk from a breast are disclosed herein. A device for expressing breast milk may comprise a breast interface including a flange configured to engage a breast and fluidly seal thereagainst, and an actuatable assembly operably coupled to the breast interface and configured to apply vacuum pressure at the breast interface. The breast interface may be configured to apply anterior compression to an anterior portion of the breast when the actuatable assembly is actuated. The flange may be configured to apply posterior compression to a posterior portion of the breast when the actuatable assembly is actuated. The posterior compression can help improve the efficiency of milk expression by reducing the retrograde flow of milk.