Abstract: A hair cleanser comprising is a mixture of conditioners, cooling agents, emulsifiers, humectants, pH balancing agents, preservatives, thickeners, and vitamins. The cleanser may also include astringents, emollients, fragrances, re-fatting agents and botanicals.

Abstract: An expanding tablet is described comprising a drug release controlling membrane material. After swallowing, the tablet hydrates and expands such that the membrane ruptures to directly expose some surfaces of the core tablet to hydrating and eroding liquids, thus generating in situ a tablet which is platform supported on non-exposed surfaces, and which releases active ingredient in approximately zero order fashion. More particularly, the dosage form is adapted for controlled release of various pharmaceuticals. A working embodiment of the tablet was a spray-coated tablet comprising a core having greater than 25% of an expandable material which expands upon exposure to an aqueous environment and at least one active ingredient, e.g., glipizide, and an outer rupturable coating surrounding the core comprising a rate release modifying membrane and a water-soluble modifier. A method for administering an active ingredient also is described.

Abstract: The invention provides a process for microencapsulating a pharmaceutical substrate comprising the steps of: a) adding insoluble or sparingly soluble particles of the substrate to be microencapsulated to a stable buffer solution having a high ionic strength; b) dissolving a membrane-forming ionic polymer in the buffer; c) forming a coacervate by adding a water-complexing compound causing phase separation of the resulting mixture; and d) allowing the deposition of the coacervate onto the substrate so as to create a coating of polymer around the substrate.

Abstract: Controlled release, multi-step drug dosage forms comprising a plurality of dose units and a plurality of separators that control release of drug from the dose units. In one embodiment, a dose unit is a single dosage amount of a drug that is electrostatically deposited onto a substrate. The dosage forms are designed to deliver a drug to exhibit a desired pharmacokinetic profile.

Abstract: The present invention concerns methods of obtaining stable lutein and its derivatives. Additionally, the invention concerns various compositions comprising lutein, lutein esters, tetrahydrocurcuminoids, and carnosic acid.

Abstract: The present invention provides a pharmaceutical formulation suitable for filling softgel capsules comprising: (a) a therapeutically effective amount of a non-steroidal anti-inflammatory drug selected from the group consisting of selected from the group consisting of (1) the propionic acid derivatives; (2) the acetic acid derivatives; (3) the fenamic acid derivatives; (4) the biphenylcarboxylic acid derivatives; and (5) the oxicams; as well as Cox 2 inhibitors and mixtures thereof; and (b) a solvent system comprising 40% to 60% by weight a polyoxyethylene ether of the formula: wherein n=1 to 6; 15% to 35% by weight of glycerin and 15% to 35% by weight water. In the case of compositions containing an NSAID having carboxyl function an alkaline hydroxide may be added to neutralize said hydroxide function.

Abstract: A method of detoxifying the egg of puffer fish for creating healthy foodstuffs which includes the steps of heating the eggs of puffer fish and ginger root at a temperature of 100-200° C. for 30-40 minutes and drying the heated egg composition, and repeating the heating and drying steps a multiplicity of times to produce a detoxified product.

Abstract: A thermoplastic layer material has at least one odor reducing surface which is treated with a carboxylic acid-based odor control agent, and which is able to withstand insults with an aqueous liquid. The acid-based odor control agent is bound to the layer material by an organosilicone polymer binder. The binder is water-insoluble, and can form a highly gas-permeable coating. The binder is also highly porous, so as to expose the odor control agent to ammonia and other odoriferous gases which it is intended to control.

Abstract: Paroxetine salt compositions having improved stability are formed by controlling the pH to 6.5 or less. The compositions can be made with the aide of water without significant coloration problems. The paroxetine salts include paroxetine hydrochloride salts but preferably use paroxetine sulfonate salts such as paroxetine methane sulfonate.

Abstract: The invention relates to carrier particles for use in pharmaceutical compositions for the pulmonary administration of medicaments by means of dry powder inhalers. In particular, the invention relates to a novel technological process for obtaining a carrier modified so as to improve the efficiency of redispersion of active particles and hence increase the respirable fraction. After the treatment of the invention, the surface of said modified carrier particles can also be coated with a suitable additive so as to further improve the respirable fraction.

Abstract: Carpeted floor covering articles comprising carpet pile fibers to which a topical antimicrobial application of solid particles has been applied either during or after product manufacture (such as part of a cleaning or treatment process) are provided. Such a topical treatment includes specific inorganic antimicrobial metal ion-based solid compounds, such as silver ion-exchange compounds, silver zeolites, and/or silver glasses, which may or may not be dispersed within a liquid medium for ease in handling and application. Such treatments also optionally include compositions of stain resistant agents, anti soil-redeposition compounds and liquids, surfactants, antistatic agents, and the like, to impart other characteristics to the target carpeted products. Such carpeted products thus exhibit excellent antimicrobial characteristics at both the surface of the carpet pile, as well as within the pile itself.

Abstract: The present disclosure is directed to compositions containing boron which are useful for a variety of purposes, including enhancing bone health, alleviating arthritis, pain, and inflammation, and producing other beneficial health effects. The disclosure is further directed to methods of preparing such compositions, methods of using (including administering) the compositions, and kits comprising the compositions. The compositions have a pH which is at least about 2 pH units less than the pKa of the boron compound.

Abstract: The use of vanillin as a hypolipidemic—a hypotriglyceridemic pharmaceutical agent over a wide range of concentration in the treatment of diabetes (type-2), cardiovascular disturbances, and obesity. Vanillin is also used as a food additive for preventing the development of such pathological conditions, particularly in young people.

Abstract: In a method for manufacturing a thin-walled, skin-contacting elastomeric article to be worn over a human body part, an article-shaped form is dipped into a latex composition that has been mixed with the extract of the plant Aloe vera forming the article. The article is processed and cured so that the extract is present within the article as one or combination of a polymer, co-polymer and filler of the article. An Aloe vera coating may be applied to at least one surface of the article.

Abstract: Methods and compositions are provided for reducing the risk of cardiovascular events in individuals who are at elevated cardiovascular risk, including individuals who have systemic lupus erythematosus. The methods comprise administering a combination of: a cholesterol-lowering agent, such as an HMG CoA reductase inhibitor; an inhibitor of the renin-angiotensin system, such as an ACE inhibitor; aspirin; and optionally one or more of vitamin B6, vitamin B12, and folic acid. Pharmaceutical formulations combining all the active agents in unit-dose form for once-daily dosing are provided.

Abstract: The present invention relates to a new layering process, in particular to a process for the manufacture of multiparticulate solid oral dosage forms based on a dry spray layering technique optionally with electrostatic attraction. The invention also relates to an apparatus for use in the process.

Abstract: A food additive composition in a ground particulate composition containing multiple vitamins, calcium citrate, sugar, minerals, herbs, at least 70% to 80% by volume of different types of grains, 10%-20% by volume of beans, berries, and cloves. Two different compositions containing dried (1) vegetables and (2) fruits are formulated, and the nutritious and flavorful additive compositions can be added to food being cooked or while eating out.

Abstract: A deodorant composition, which comprises a pyrone compound given by formula: wherein R represents a C3-C10 acyclic hydrocarbyl group, as an active ingredient, is very effective for removing bad smell.

Abstract: A hair relaxer and conditioner consisting of natural components such as coffee, walnut oil, fish oil carnauba milk and honey. The components are mixed in predetermined proportions to provide hair straightening without damage to the hair and scalp. The pH of the product is between 4.70 and 5.30.

Abstract: Iron oxide-silicon dioxide-titanium dioxide mixed oxide is produced by burning vapourable compounds of iron, silicon and titanium together in a hydrogen/oxygen flame. The mixed oxides may be used as UV absorbers in cosmetics.