Abstract: A method of isotope-labelling a microbiota sample. It involves providing a first microbiota sample that was obtained from a given source; exposing the first microbiota sample to an isotope enriched medium; and culturing the exposed first microbiota sample in the isotope enriched medium to obtain an isotope-labelled microbiota sample, wherein the isotope labelled metaproteome of the isotope-labelled microbiota sample is taxon specific for taxa present in the first microbiota sample when initially obtained from the given source.
Type:
Grant
Filed:
January 27, 2021
Date of Patent:
March 19, 2024
Assignee:
UNIVERSITY OF OTTAWA
Inventors:
Joseph Michel Daniel Figeys, Alain Christophe Stintzi, David R. Mack, Xu Zhang, Zhibin Ning
Abstract: The present specification discloses pest control compositions, articles of manufacture, containers or kits comprising such compositions, and methods and uses to control a population of invertebrate pests from a mammal, location, plant, structure treated of such pest control compositions.
Abstract: A method of making an electron beam irradiated osteoinductive implant is provided. The method comprises exposing an osteoinductive implant containing demineralized bone matrix (DBM) fibers to electron beam radiation at a dose of from about 10 kilograys to 100 kilograys for a period of time. The electron beam irradiation reduces microorganisms in the osteoinductive implant, and the electron beam irradiated osteoinductive implant retains osteoinductive properties. Methods of implantation and an irradiated osteoinductive implant are also disclosed.
Type:
Grant
Filed:
August 16, 2021
Date of Patent:
March 5, 2024
Assignee:
Warsaw Orthopedic, Inc.
Inventors:
Kelly W. Schlachter, Erick Vasquez, Daniel A. Shimko
Abstract: An apparatus and method for detecting an analyte of interest using paper spray mass spectrometry includes a spray material; a sample on the spray material including an enzyme of interest; a solvent to hydrate the sample, promote enzymatic activity, and extract analytes of interest from the sample; a substrate specific to the enzyme of interest, wherein any of the spray material and the solvent includes the substrate; a voltage source to apply a voltage to the spray material to create charged droplets of a mixture containing the sample; and a mass spectrometer to perform spectrometry on the droplets to perform any of: identify the analytes of interest in the sample; and measure a level of inhibition in any enzymes contained in the sample.
Type:
Grant
Filed:
October 26, 2021
Date of Patent:
February 27, 2024
Assignee:
The United States of America as Represented by the Secretary of the Army
Inventors:
Trevor G Glaros, Elizabeth S Dhummakupt, Phillip M Mach, Daniel O Carmany
Abstract: The present disclosure discloses a preparation method for hyperthermophilic aerobic fermentation inoculant prepared by using sewage sludge, the method includes the following steps: carrying out fermentation after the activation of hyperthermophilic aerobic bacteria, removing the supernatant from the fermentation products, and adding the protective agent and stirring until uniform, drying to obtain a product, pulverizing the product by a pulverizer, and sieving the product before sub-packing. The solution of the present disclosure has the following advantages.
Abstract: The invention relates to chitin, a hydrolysate and a method for the production of at least one desired product from insects. More specifically, the invention relates to a method for the production of at least one desired product from insects, comprising an insect cuticle pressing step, followed by the enzymatic hydrolysis of the insect cuticles using a proteolytic enzyme.
Type:
Grant
Filed:
December 30, 2015
Date of Patent:
February 6, 2024
Inventors:
Nathalie Berezina, Antoine Hubert, Fabrice Berro, Jean-Gabriel Levon, Karine Le Roux, Cecilia Socolsky, Lorena Sanchez, Sophie Laurent
Abstract: The invention relates to a biological indicator for determining the efficacy of a steam or heat sterilization process, and its method. The biological indicator comprises microbial spores (a), at least one sensor protein exogenous to the microbial spores (b), one fluorophore (c), and a culture medium (d). The invention also refers to the method of use of this biological indicator.
Type:
Grant
Filed:
August 16, 2019
Date of Patent:
January 30, 2024
Assignees:
Terragene LLC, Terragene SA
Inventors:
Adrian Jesus Rovetto, Esteban Lombardia, Pablo Ravasi
Abstract: The present invention relates to compositions and methods for increasing the health of aquatic animals comprising one or more selected bacterial strains.
Type:
Grant
Filed:
April 9, 2014
Date of Patent:
January 30, 2024
Assignee:
Novozymes A/S
Inventors:
David Drahos, Christian Munch, Lene Venke Kofod
Abstract: Provided is Lactobacillus kefiri MSR101, having the accession member being CGMCC No. 17506. The strain has acid resistance, bile salt resistance, resistance to phenol, antibiotic resistance, antioxidant activity, cell surface hydrophobicity, adhesion to intestinal epithelial cells, and a cholesterol-lowering function.
Type:
Grant
Filed:
March 18, 2020
Date of Patent:
October 17, 2023
Assignee:
SHENZHEN UNIVERSITY
Inventors:
Liqing Zhao, Muhammad Shahid Riza Rajoka
Abstract: The present specification discloses papermaking additive compositions, articles of manufacture, containers or kits comprising such compositions, and methods and uses to increase separation of cellulose fibers from a pulp, to remove one or more impurities and/or one or more contaminates from a pulp and/or a paper material and to remove an ink from a pulp and/or a paper material.
Abstract: The present invention provides a process for the treatment of sewage sludge with enzymes, which process comprises treating a sewage sludge resulting from the treatment of municipal or industrial waste water with a composition comprising a fermentation supernatant product from a Saccharomyces cerevisiae culture and a non-ionic surfactant, wherein said fermentation supernatant product is free of active enzymes, at conditions suitable for generating said active enzymes from said sewage sludge in situ.
Abstract: The present specification discloses plant agent compositions, articles of manufacture, containers or kits comprising such compositions, and methods and uses to control a causal agent of a plant disease or increasing plant growth and/or fruit production.
Abstract: A skin care composition is disclosed comprising at least one exopolysaccharide (EPS) originating from a microbial mat, the EPS being in a concentration of about 0.001% w/w to about 1.5% w/w of the composition. Uses and methods of use thereof. In specific embodiments, the EPSs are derived from microorganisms isolated from microbial mats found in French Polynesia. The composition is useful in reducing signs of skin aging and environmental damage by altering skin cell metabolism and improving hydration.
Abstract: Ear corn is picked from corn fields by ear corn harvesters and transported to a central shelling station associated with an ethanol manufacturing facility. Shelled corn from the central shelling station is processed into ethanol at the ethanol manufacturing facility, and corn cobs from the central shelling station are burned to provide process heat for the ethanol manufacturing process. Energy is conserved and costs are reduced during the picking and shelling of the ear corn and by the burning of cobs for process heat.
Abstract: The present invention relates to compositions and methods for the remediation of contaminated solids and liquids. In particular, embodiments of the present invention relate to the bioremediation of solids and liquids by a composition comprising a biocatalyst or mixture of biocatalysts. The present invention also relates to methods for producing the bioremediation compositions and methods for applying the bioremediation compositions to contaminated sites, including treatment, storage, and disposal facilities, as well as various contaminated water sources, such as aquifers and reservoirs.
Abstract: The present invention is related to novel methods for identifying a population of subjects that are at risk for developing of atopic allergic diseases, such as atopic dermatitis, and to the prevention and treatment of these allergic diseases.
Type:
Grant
Filed:
February 7, 2018
Date of Patent:
July 25, 2023
Assignee:
National Jewish Health
Inventors:
Donald Y. M. Leung, Elena Goleva, Evgeny Berdyshev
Abstract: The disclosure provides methods using mixed substrate cofeeding for bioproduct synthesis, which enables faster, more efficient, and higher yield carbon conversion in various organisms.
Type:
Grant
Filed:
June 29, 2018
Date of Patent:
May 16, 2023
Assignee:
Massachusetts Institute of Technology
Inventors:
Junyoung Park, Nian Liu, Gregory Stephanopoulos
Abstract: A method for activating a cell-signaling pathway of interest in a cell, including applying a time-modulated localized alternating current electrical field to the cell, wherein the amplitude and frequency of the localized alternating current electrical field is selected to activate the cell signaling pathway of interest, thereby activating the cell signaling pathway.
Type:
Grant
Filed:
November 5, 2019
Date of Patent:
April 25, 2023
Assignees:
Arizona Board of Regents on behalf of Arizona State University, The Regents of the University of California
Inventors:
Quan Qing, John Albeck, Liang Guo, Min Zhao, Houpu Li
Abstract: The invention belongs to the field of microbes and specifically relates to a myroides odoratimimus biocontrol strain for efficiently degrading aflatoxin and an application thereof. A myroides odoratimimus biocontrol strain 3J2MO is preserved at the China Center for Type Culture Collection (referred to as CCTCC) on Jun. 13, 2017 with preservation number CCTCC No. M 2017329. The myroides odoratimimus biocontrol strain of the invention can effectively degrade aflatoxin and may be configured to degrade aflatoxin and treat aflatoxin pollution of food crops.
Type:
Grant
Filed:
May 29, 2020
Date of Patent:
April 11, 2023
Assignee:
OIL CROPS RESEARCH INSTITUTE, CHINESE ACADEMY OF
AGRICULTURAL SCIENCES
Abstract: The present invention relates to a method for extracting nucleic acids from a biological sample, and the extraction method presents a novel method for effectively extracting nucleic acids. When nucleic acids are extracted from biological samples in the related art, various impurities present in the biological samples are not properly removed, such that the purification rate is low, but the present invention provides a method for extracting nucleic acids from a biological sample of which the bacteria, virus and nucleic acid recovery rates are enhanced, by adding a surfactant and a sodium sulfate (Na2SO4) solution in a biological sample disruption step and a purification step, thereby enabling pathogens to be detected more sensitively and accurately.