Patents Examined by T. Wissendorf
  • Humoral hypercalcemic factor antagonists with modification at position 13 . . .
    Patent number: 5087562
    Abstract: The present invention relates to the use of peptide analogues as inhibitors of their respective naturally occurring peptides. The structure of the peptide hormone analogues is exemplified by human humoral hypercalcemic factor (hHCF), wherein Lys.sup.13 is modified so as to produce HCF analogues which can inhibit the action of HCF.
    Type: Grant
    Filed: April 25, 1990
    Date of Patent: February 11, 1992
    Assignee: Merck & Co., Inc.
    Inventors: Michael Rosenblatt, Eliahu Roubini, Michael Chorev, Ruth F. Nutt