Abstract: A wireless communication and global location enabled intelligent health monitoring system comprising of a plurality of wireless medical sensor apparatus that include an active sensor, a transducer, a digital-to analog converter, a frequency synthesis, a plurality of bandpass filter, a plurality of linear power amplifier, a signal mixer, a packaged antenna, a thin-film battery, for measuring patient vital signs on different parts of patient body, and a main processing unit apparatus that contains a system software including intelligent controller which uses active, real-time monitoring method to measure and process vital signs and location information for providing alert on location and transmitting emergency request to remote patient monitoring station for immediate assistance. Intelligent controller and all application tasks of said system software are running under separate parallel execution threads.