Patents Examined by Tania Ismail
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Patent number: 11298506Abstract: A method of treating an anatomical cavity of a patient comprises introducing an infusion/aspiration catheter into the patient, such that a plurality of arms of the catheter reside within the anatomical cavity, delivering a fluid into the at least one of a connector, such that fluid exits the at least one fluid port of at least one of the arms, thereby infusing the anatomical cavity with the fluid, and aspirating the fluid into the at least one fluid port of at least one of the arms, such that the fluid exits the connector(s).Type: GrantFiled: September 17, 2018Date of Patent: April 12, 2022Assignees: STRYKER CORPORATION, STRYKER EUROPEAN OPERATIONS HOLDINGS LLCInventors: Stephen Porter, Jon Schabert
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Patent number: 11285268Abstract: A drug delivery device comprises a housing and a dose sleeve located within the housing, the dose sleeve being configured to move helically within the housing as a medicament dose is dialled into or delivered from the drug delivery device. A dose setting arrangement is coupled to the dose sleeve and is configured to cause helical movement of the dose sleeve as a medicament dose is dialled into the drug delivery device through rotation of a dose dial forming part of the dose setting component. A dose delivery arrangement comprising a dose button is coupled to the dose sleeve and is configured to cause delivery of medicament with helical movement of the dose sleeve and without rotation of the dose dial when the dose button is actuated. A first sensor arrangement is configured for detecting a rotation of the dose dial relative to the housing. A second sensor arrangement is configured for detecting movement of the dose sleeve relative to the housing.Type: GrantFiled: January 5, 2017Date of Patent: March 29, 2022Assignee: Sanofi-Aventis Deutschland GMBHInventor: Christian Rehbein
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Patent number: 11266780Abstract: A control system for administration of a drug comprises a drug administration actuator for administering the drug to a patient at a controllable dosage; a monitor for measuring an effect of the drug on the patient; and a controller configured to determine a control signal to the drug administration actuator; wherein the controller is configured to implement a closed loop model-predictive control scheme comprising, for each of a series of time steps, minimizing a cost function subject to one or more constraints to determine the control signal, the cost function based at least in part on a reference level and the monitor measurement; wherein the control signal is used as an input to an auxiliary model to estimate at least one concentration level of the drug in the patient; and wherein the constraints comprise at least one constraint on the estimate of the concentration level of the drug.Type: GrantFiled: November 23, 2016Date of Patent: March 8, 2022Assignee: University of British ColumbiaInventors: Guy Dumont, Mark Ansermino, Sara Khosravi, Nicholas West
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Patent number: 11266788Abstract: Sensing systems, devices and methods are disclosed for determining the relative movement of first and second members of a medication delivery device which are proportional to the amount of a dose set and/or delivered by operation of the medication delivery device. A sensor is coupled with the first member. A pair of targets is coupled with the second member. Each target comprises an array of teeth which move through an area sensed by the sensor. The sensor thereby detects characteristic values of a sensed parameter corresponding to the combined relative positions of the first and second members. The sensing system outputs this information to a processor which determines the amount of the dose set and/or delivered. Related medication delivery devices and methods are also disclosed.Type: GrantFiled: April 12, 2017Date of Patent: March 8, 2022Assignee: Eli Lilly and CompanyInventors: Roy Howard Byerly, Russell Wayne Perkins
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Patent number: 11253650Abstract: An electrical information device and a medicament delivery device are presented. The electrical information device includes at least one start of delivery sensor configured to detect a distal axial movement of a release member of the medicament delivery device. The release member is configured to be distally moved when an activator member of the medicament delivery device 1 is forced distally. The electrical information device also includes at least one information communication unit, which is configured to communicate information related to the medicament delivery. The electrical information device further includes at least one activation unit, which is configured to activate the at least one information communication unit based on a detected distal axial movement of the release member.Type: GrantFiled: December 15, 2016Date of Patent: February 22, 2022Assignee: SHL MEDICAL AGInventors: Daniel Carlsson, Daniel Säll
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Patent number: 11141570Abstract: An intravenous catheter introducer for medical use having a body, a frontal attachment that is disposed in transverse sliding engagement with a front part of the body, a hub tube assembly that is releasably supported by the frontal attachment, and a retractable catheter insertion needle and needle holder that are biased rearwardly by a spring offset laterally from the needle axis, whereby lateral repositioning of the body relative to the frontal attachment following vascular insertion moves a needle retraction cavity disposed inside the body into substantial coaxial alignment and causes the needle holder to be retracted into the needle retraction cavity.Type: GrantFiled: March 29, 2018Date of Patent: October 12, 2021Assignee: Retractable Technologies, Inc.Inventors: Thomas J. Shaw, Mark Small, Ni Zhu
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Patent number: 11141539Abstract: An injector for delivering liquid can include a body having a proximal end, a distal end, a longitudinal axis, and a track follower adjacent to the proximal end. A plunger can be disposed at least partially within the body and movable with respect to the body along the longitudinal axis. An actuator can be positioned at the proximal end of the body and operably connected to the plunger. The actuator can include a track having a first portion and a second portion. The first portion can limit travel of the actuator along the longitudinal axis to deliver a first predetermined amount of the liquid. The second portion can limit travel of the actuator along the longitudinal axis to deliver a second predetermined amount of the liquid. The actuator can be positionable to selectively control displacement of the plunger pursuant to the first portion or the second portion of the track.Type: GrantFiled: December 14, 2016Date of Patent: October 12, 2021Assignee: Merck Sharp & Dohme Corp.Inventors: Jeffrey C. Givand, Peter A. Basile
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Patent number: 11129959Abstract: The present invention relates generally to medical devices and, in particular, to an introducer sheath that includes a shaft including a tubular portion, an expandable portion coupled to the tubular portion and a longitudinal axis. Additionally, the expandable portion includes a first pair of leaflets and a second pair of leaflets and both the first pair of leaflets and the second pair of leaflets extend along the longitudinal axis. Additionally, the second pair of leaflets are spaced radially inward of an inner surface of the first pair of leaflets and the expandable portion is designed to shift between a first configuration and a second radially expanded configuration.Type: GrantFiled: February 15, 2019Date of Patent: September 28, 2021Assignee: Boston Scientific Scimed, Inc.Inventors: Matthew Hart, Corey N. Meyer, Derek Kenneth Larson, Benjamin Breidall, Kevin Martin, Victoria Velez, Nathan Adams
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Patent number: 11116301Abstract: A device for treating human keratin materials that delivers a cosmetic or dermatological composition onto the latter together with the application of an electric current, in particular an electrophoresis device, the composition applied being contained in a cartridge carried by the device, the cartridge having a body that forms a reservoir and a piston through which a drive screw passes and which can move in the body under the effect of the relative rotation of the screw and the piston, the device comprising an electric drive motor for bringing about this relative rotation of the screw and of the piston, and an electronic circuit for controlling the electric motor.Type: GrantFiled: December 6, 2016Date of Patent: September 14, 2021Assignee: L'OREALInventors: Laure Thiebaut, Franck Mandica, Hélène Pernot, Johan Sabattier
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Patent number: 11116894Abstract: A medical pump device for delivering a medical fluid includes a base body and elastomeric hollow membrane secured to the base body and arranged in such a way that a pump volume for filling with medical fluid is formed between the base body and hollow membrane. The hollow membrane, in an at least partially filled state of the pump volume, is elastically extended and exerts a delivery pressure on the pump volume. The medical pump device has a sensor system set up to determine the extension of the hollow membrane such that, by using the extension that is thus determined, filling level information concerning the filling state of the pump volume is determined. The medical pump device can be used in infusion or transfusion arrangements.Type: GrantFiled: March 26, 2018Date of Patent: September 14, 2021Assignee: B. BRAUN MELSUNGEN AGInventor: Jens Stettner
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Patent number: 11110004Abstract: A phacoemulsification cutting tip, including a rigid tubular portion and a flexible and expandable tip portion located distal to the rigid tubular portion. The flexible and expandable tip portion presents an axial length and an unexpanded radius and is formed such that the axial length shortens while the unexpanded radius increases when differential pressure due to an occlusion of an opening of the flexible tip portion exists.Type: GrantFiled: September 17, 2018Date of Patent: September 7, 2021Inventor: William F. Wiley
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Patent number: 11103636Abstract: An insertion mechanism for a wearable drug delivery device includes a needle hub, a needle coupled to the needle hub, a flexible boot removably coupled to the needle hub, and a cannula coupled to the flexible boot. The needle hub, the needle, the flexible boot, and the cannula are movable between a first position and a second position. Upon moving the needle hub, the needle, the flexible boot, and the cannula from the first position to the second position, the cannula engages a floor member to restrict movement of the cannula and the flexible movement towards the first position.Type: GrantFiled: June 22, 2018Date of Patent: August 31, 2021Assignee: AMGEN INC.Inventors: Jerome Olivas, Justin Harris, Sudeshna Dutta Ray, David Coleman, Eoghan McManus
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Patent number: 11097054Abstract: A cartridge (10) for injecting a pharmaceutical solution includes at least one flexible small bag (18, 22) made of thin film walls, having a chamber (12, 14) containing a pharmaceutical substance (S, P, L) and having a head surface (37) being outwardly convex. A syringe (100) for injecting a pharmaceutical solution (S) includes a body (102) extended along a main axis (X), an accommodating space (120) to accommodate a cartridge (10), and a plunger (110) with a head (113) being dome-shaped and convex towards the space (120), preferably asymmetrical with respect to the main axis (X). An injection kit for injecting a pharmaceutical solution including a syringe (100) and at least one cartridge (100).Type: GrantFiled: January 12, 2017Date of Patent: August 24, 2021Assignee: OROFINO PHARMACEUTICALS GROUP S.R.L.Inventor: Ernesto Orofino
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Patent number: 11083849Abstract: An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises: a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; and a cord arranged to connect the plurality of plunger elements, wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force.Type: GrantFiled: November 21, 2016Date of Patent: August 10, 2021Assignee: Sanofi-Aventis Deutschland GMBHInventors: Stefan Wendland, Michael Harms
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Patent number: 11076984Abstract: A method includes inserting a flexible cannula between a sclera and a choroid of an eye. The needle is advanced from a distal end of the flexible cannula, such that the needle pierces the choroid to access a subretinal space of the eye. The needle is used to aspirate fluid from the subretinal space. The fluid may be present from a retinal detachment, a macular hemorrhage, or other condition present before the procedure begins. The method may further include injecting the fluid in the subretinal space via the needle, in which case the fluid may be a balanced salt solution or other bleb fluid. The method may further include injecting a therapeutic agent into the subretinal space after aspirating the bleb fluid. The volume of injected bleb fluid may be greater than the volume of injected therapeutic agent.Type: GrantFiled: March 5, 2018Date of Patent: August 3, 2021Assignee: GYROSCOPE THERAPEUTICS LIMITEDInventors: Daniel W. Price, Brendan J. Oberkircher, Daniel J. Prenger, Geoffrey King, Isaac J. Khan, Michael F. Keane, Benjamin L. Ko
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Patent number: 11020194Abstract: The present invention provides a minimally invasive surgical instrument with a terminal steerable mechanism, comprising an intervention device, a control device and one or more wires. The strip-shaped intervention device sequentially includes a main section, a flexible section and an operation section from the top to the end. The control device includes a sphere with a preset rotational degree of freedom, and an operating lever connected to the sphere. Said one or more wires are extended along the main section of the intervention device. Here, the second ends of said at least one or more wires are connected to the flexible section or the operation section of the intervention device, and the first ends thereof are connected to at least a part of the control device.Type: GrantFiled: May 15, 2018Date of Patent: June 1, 2021Assignee: NATIONAL CHIAO TUNG UNIVERSITYInventors: Bing-Shiang Yang, Chao-Che Wu
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Patent number: 10987455Abstract: The present invention relates to a breast pump (1) for extracting milk from a female breast comprising an expression kit (2), a container (5) connected to the expression kit (2), and a vacuum unit (6) connected to the expression kit (2), wherein the combined volumes of the expression kit (2), the container (5), the vacuum unit (6) and the connections thereof define a system air volume, and a vacuum pressure sensor for determining volume changes in the system air volume in response to changes in vacuum pressure.Type: GrantFiled: December 15, 2016Date of Patent: April 27, 2021Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Arnold Aalders, Arjan Teodor Van Wieringen, Hassan El Barakat
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Patent number: 10980937Abstract: A dosing unit for use in an ambulatory infusion system, the dosing unit including: a dosing cylinder and a piston arranged inside the dosing cylinder and in a sliding displaceable manner along a displacement axis. The piston is convertible from a storing configuration into an operational configuration, wherein a circumferential sealing member of the piston is mechanically relieved in the storing configuration and is in sealing and sliding engagement with a circumferential inner surface of the dosing cylinder in the operational configuration. The dosing unit includes a configuration switch member in operative mechanical coupling with the piston, the configuration switch member being movable relative to the piston from a storing position into an operational position, thereby switching the piston configuration from the storing configuration to the operational configuration.Type: GrantFiled: February 28, 2018Date of Patent: April 20, 2021Assignee: Roche Diabetes Care, Inc.Inventor: Hanspeter Niklaus
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Patent number: 10960177Abstract: A medical device used to percutaneously gain access to a targeted site within a living body, for example the left ventricle of the heart. The device is comprised of an inner tubular member, outer tubular member, and an adjustable control handle. The control handle can precisely control the relative position of the inner tubular member relative to the outer member by providing feedback to the operator. This feedback provided by the control handle allows the operator to precisely maneuver the catheter within a body and change the shape of the catheter system without taking his/her eyes off the task that he/she is performing. The control handle is designed to precisely change the catheter system from one tip shape to another tip shape and back. Described herein are methods to use such devices.Type: GrantFiled: June 28, 2019Date of Patent: March 30, 2021Assignee: PROMEDICA HEALTH SYSTEM, INC.Inventor: P. Kasi Ramanathan
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Patent number: 10953194Abstract: A medical device and use thereof provide percutaneous access to a targeted site within a living body, for example the left ventricle of the heart. The device includes an inner tubular member, outer tubular member, and an adjustable control handle. The control handle can precisely control the relative position of the inner tubular member relative to the outer member by providing feedback to the operator. This feedback provided by the control handle allows the operator to precisely maneuver the catheter within a body and change the shape of the catheter system without taking his/her eyes off the task that he/she is performing. The control handle is designed to precisely change the catheter system from one tip shape to another tip shape and back.Type: GrantFiled: February 28, 2018Date of Patent: March 23, 2021Assignee: PROMEDICA HEALTH SYSTEM, INC.Inventor: P. Kasi Ramanathan