Abstract: Medical devices and methods for controlling the flow of fluid from wounds are disclosed herein. The medical device can have an adhesive pad defining a catheter-receiving opening, a flexible elongate tensioner, and a tensioner retainer. The tensioner retainer is configured to hold the flexible elongate tensioner such that the adhesive pad applies sufficient pressure to a subject's skin to press the subject's tissue toward a catheter when the catheter is positioned in the catheter-receiving opening and the adhesive pad is adhered to the subject's skin.

Abstract: Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided.

Abstract: An apparatus for automatic ejection of a fluid includes a drive train for automatically ejecting the fluid from a fluid reservoir through an ejection channel, and a control unit for controlling the apparatus. The control unit is configured to detect failures of drive train actuation steps, during which the drive train is actuated for priming or fluid dose ejection. The control unit is further configured to control the apparatus as a function of an actuation step failure number. The actuation step failure number is the number of failed drive train actuation steps since the last successful drive train actuation step.

Abstract: Transdermal patches and devices for delivery of therapeutic drug and/or cosmetic formulations through an intact or porated skin barrier are described. Active-infusion delivers controlled dosing over a period of time to provide long-term efficacy. Methods and devices for preparing active-infusion patches for controlled dose delivery by nonelectronic devices and methods of skin poration that is safe and painless are described.

Abstract: A drive assembly for a drug delivery device is provided, including a piston rod which is moveable in a distal direction in order to deliver a dose of medication, and including a drive element which is configured to cause a movement of the piston rod. The drive assembly further includes a decelerating mechanism which is configured to decelerate the movement of the drive element such that the movement of the piston rod is decelerated during the dispense of a dose. The decelerating mechanism includes a decelerating element which is fixed with respect to a housing of the drug delivery device at least during the dispense of a dose and the drive element, wherein the drive element is configured to rotate with respect to the housing during the dispense of a dose, and wherein the decelerating element and the drive element rub against each other during the dispense of a dose.

Abstract: A support apparatus for supporting a trocar while the trocar extends through a body wall of a patient includes an inflatable collar and a slidable abutment collar commonly connected for engagement onto the trocar following which the slide collar is released to slide along the trocar. The inflatable collar is inflated to a set size by a manually operable pump on the slidable collar operated by squeezing finger abutments together up to a latch so that threaded portion expels the inflation fluid. The abutment member is shaped to be received on an outer surface of the trocar and adjustable longitudinally of the trocar sleeve so as to be located at a selected position by a manually movable latch collar. The inflatable collar and slidably collar are held connected by a manually operable release.

Abstract: Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided.

Abstract: A syringe includes a barrel having a distal end, a proximal end, and a sidewall extending therebetween along a longitudinal axis. At least one engagement member protrudes from a terminal portion of the sidewall in a proximal direction along the longitudinal axis. The at least one engagement member tapers axially in a direction from the distal end toward the proximal end. The at least one engagement member is configured for engagement with a locking mechanism of a fluid injector to releasably lock the syringe with the fluid injector. A taper of the at least one engagement member is configured to rotationally guide the syringe into alignment with the locking mechanism and axially eject the syringe upon rotation of the syringe. The locking mechanism operatively engages the at least one engagement member regardless of an orientation of the syringe about the longitudinal axis relative to the injector.

Abstract: The present invention is directed to a device for the expression of a hemostatic powder having an elongated reservoir with a manual air pump, such as a bellows, at a proximal end and an expression port at a distal end. A porous filter is slidably disposed within the reservoir between the bellows and plunger and the expression port, and a spring is disposed within the reservoir between the air pump and the plunger. The powder is disposed within the reservoir between the porous filter and the expression port, and the pump is in a fluid communication with the expression port through the porous filter and through the powder.

Abstract: A cyclic aperture flow regulator system has an adjustable fluid aperture in a fluid path connecting the aspiration port of a surgical probe with a vacuum source. The cross-sectional area of the fluid aperture can be modified by an actuator. The actuator is controlled to modify the cross-sectional area of the adjustable fluid aperture in cycles. During each cycle, the fluid aperture cross-sectional area is substantially reduced or closed. The cycles occur at a rate fast enough to produce a substantially steady flow, with minimum flow ripple and pressure ripple.

Abstract: A bolus control device for use with an injection device includes a valve body having a proximal end opposite a distal end. The valve body defines a fluid channel therethrough to allow a passage of medical fluid from the proximal end to the distal end. A connector at the proximal end and is configured for connecting to a fluid inlet line. A connector subassembly at the distal end and is configured for connecting to a fluid outlet line. A compressible check valve is disposed within the fluid channel, such that the compressible check valve is adjustable to control a cracking pressure at which the compressible check valve closes.

Abstract: An assembly for a drug delivery device includes a first member and an attenuation member. The first member includes a main body and an elastically displaceable feature connected to the main body. The attenuation member mechanically cooperates with the elastically displaceable feature to influence the force which has to be exerted on the elastically displaceable feature to displace the elastically displaceable feature elastically with respect to the main body. An attenuation member can be used in a drug delivery device to tune the force required to elastically displace an elastically displaceable feature of a first member of the drug delivery device by bringing the attenuation member into mechanical cooperation with the elastically displaceable feature.

Abstract: A drive mechanism of a drug delivery device for dispensing of a dose of a medicament, includes an elongated housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge to displace the piston in axial distal direction, a drive sleeve rotatably supported in the housing at least in a dose incrementing direction against the action of a spring element, and a ratchet mechanism to rotatably fix the drive sleeve relative to the housing. A first ratchet body has a first and a second ratchet element to alternately engage with a toothed profile of a second ratchet body. One of the first and second ratchet bodies is operably engaged with the housing and wherein the other one of the first and second ratchet bodies is operably engaged with the drive sleeve.

Abstract: An injection aid for use with an injection device, such as a safety syringe, for example, is disclosed. The injection aid employs a flexible clip-based design to compensate for manufacturing tolerances associated with the injection device. The injection aid includes a body and a lever mounted to the body, the lever being configured to rotate about the body. The injection aid may further include gears rotate with rotation of the lever, and which function to remove a needle shield from the injection device. The body positions the injection device so as to ensure consistent injection depth.

Abstract: A cyclic aperture flow regulator system has an adjustable fluid aperture in a fluid path connecting the aspiration port of a surgical probe with a vacuum source. The cross-sectional area of the fluid aperture can be modified by an actuator. The actuator is controlled to modify the cross-sectional area of the adjustable fluid aperture in cycles. During each cycle, the fluid aperture cross-sectional area is substantially reduced or closed. The cycles occur at a rate fast enough to produce a substantially steady flow, with minimum flow ripple and pressure ripple.

Abstract: The invention relates to a drive mechanism (9) for a needle insertion arrangement (1), the drive mechanism (9) including:—a cross beam (16) linearly movable in a distal direction (D) and a proximal direction (P) for moving an injection needle (2),—an actuator (5),—a slider (12) coupled to the actuator (5) and linearly movable in a transversal direction (T) at right angles relative the distal direction D and the proximal direction D,—a cam (14) on one of the cross beam (16) and the slider (12),—a guide track (13) in the other one of the cross beam (16) and the slider (12) adapted to engage the cam (14), the guide track including a sloped section (13.3) such that the cross beam (16) is moved on movement of the slider (12).

Abstract: A safety device for shielding a medical needle, includes a hand grip element; a cannula held at the hand grip element; a base with laterally protruding, flat wings, the base having a guide opening which is spaced apart from the underside and in which the cannula is guided; and a connecting structure which connects the handle element with the base and includes two elongated sections connected in a row with one another by at least one joint and the connecting structure is connected at one end by at least one joint with the hand grip element and, at the other end, by at least one joint with the base, the elongated section of the connecting structure, which is connected with the base has a wall element which protrudes transversely at its base end, and the connecting structure can be unfolded from a first state into a second extended state.

Abstract: An injection pen (1) includes a housing (2), a lead screw (75), a dose set member (6), a setback member (17), and a rotatable driver (60). The lead screw (75) is axially moveable in the housing (2). The dose set member (6) is connected to the housing (2) for dose setting and dose correcting. The setback member (17) is operatively connected to the dose set member (6). The rotatable driver (60) is operatively connected to the setback member (17) and the lead screw (75). The driver (60) is prevented from rotating during dose setting and dose correcting, and the driver (60) rotates during an injection to axially move the lead screw (75).

Abstract: An injection pen (1) includes a housing (2), a lead screw (75), a dose set member (6), a setback member (17), and a rotatable driver (60). The lead screw (75) is axially moveable in the housing (2). The dose set member (6) is connected to the housing (2) for dose setting and dose correcting. The setback member (17) is operatively connected to the dose set member (6). The rotatable driver (60) is operatively connected to the setback member (17) and the lead screw (75). The driver (60) is prevented from rotating during dose setting and dose correcting, and the driver (60) rotates during an injection to axially move the lead screw (75).

Abstract: An infusion set includes a first infusion line set that forms a first infusion line with an injection port; and a connector including a male connector end that is insertable into the injection port, a female connector end to which a second infusion line can be connected, a flow channel, and a partition. The injection port and the connector are configured such that, when the male connector end of the connector is inserted into the injection port, the flow channel of the connector is divided by the partition into an in-flow channel configured to let in a liquid from the injection port in the first infusion line and an out-flow channel configured to let out the liquid that has entered the in-flow channel to the injection port.