Abstract: Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.

Abstract: Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently “tune” the brain and affect mood, focus, and cognition of subjects.

Abstract: The present disclosure pertains to automatically predicting a slow wave response of a subject to sensory stimulation during a sleep session. The sensory stimulation may be delivered to the subject upon detection of deep NREM sleep. The sensory stimulation may be auditory, haptic, visual, or other stimulation. The system delivers stimulation to the subject in blocks of stimulation separated from one another be intra-block intervals. The blocks are separated from each other by inter-block stimulations. The system compares the stimulated slow wave activity of the subject to the unstimulated slow wave activity of the subject. The system may update the stimulation parameters based on the comparison and deliver a subsequent block stimulation. Once the comparison indicates that the stimulated slow wave activity is significantly different from the unstimulated slow wave activity, the system may apply continuous fixed sensory stimulation to the user according to the most recent stimulation parameters.

Abstract: The present invention includes an intraoral tool, including one or more selected solid or inflatable inserts targeted to provide a low load prolonged stretch to orofacial musculature that may be coupled to tool handle or tool mounting bracket, wherein the intraoral tool is configured for a delivery of intraoral treatment, such as a stretch to a patient's facial injury or disorder and configured to permit manipulation of the insert in the patient's mouth.

Abstract: Wearable devices can be used to provide therapy to users and/or to monitor various physiological parameters of the user. In some cases, therapy can be triggered automatically based on the monitored physiological parameters reaching or exceeding predefined thresholds.

Abstract: Systems and devices for continuous heating combined with oscillatory magnetic stimulation of the ST36 acupoint and/or other acupoint(s) by noninvasive infrared heating and transcutaneous magnetic field stimulation, and applied to the treatment of several physical conditions.

Abstract: An insertable cardiac monitor (ICM) with induction-based recharging capabilities and a transmitting coil for recharging the same are disclosed. The length of the monitoring performed by the ICM is extended and the functionality of the ICM enhanced, by including an internal energy harvesting module that allows for charging the ICM at a high speed without burning the patient or overheating components of the ICM. Internally, the energy harvesting module includes at least two overlapping receiving coils that are spaced to be orthogonal to each other and that have a tilt angle of substantially 45°. Such overlapping wire combination allows to minimize mutual inductance of the solenoid coils and increase the rate at which energy can be provided to the energy harvesting module. Further, the rate at which the energy is transmitted from the outside can be increased by defining in a transmitting coil a substantially triangular gap.

Abstract: A flexible neuromodulation device and method capable of varying a neuromodulation therapy in order to prevent, delay, or control a sexual emission, and/or increasing an intensity of a sexual climax.

Abstract: Disclosed herein is a radiotherapy apparatus for delivering radiation to a patient. The apparatus comprises a gantry, a source of radiation attached to the gantry and configured to emit radiation along a radiation axis, a support structure for supporting the gantry, and a gantry rotation mechanism positioned between the support structure and the gantry. The gantry rotation mechanism is configured to rotate the gantry about a gantry rotation axis, and tilt the gantry with respect to the gantry rotation axis such that the radiation axis is non-perpendicular with the gantry rotation axis.

Abstract: The present invention relates to a kit suitable for preparing a sustained release composition, in particular for preparing a sustained release composition comprising spermatozoa embedded within an alginate matrix.

Abstract: Pelvic implant having a frame with two arms and a sheet are disclosed. The sheet may be held under tension in the assembled implant. The implant may be planar (flat) or may be non-planar. The implant may be contoured laterally. A curved non-planar implant may be convex or concave in a rostro-caudal direction. The implants may (optionally) include two additional arms and a second sheet for supporting a urethra and/or a bladder neck. Methods for constructing and assembling the implants are disclosed. A method ultrasonically welding the frame of the implant without thermally damaging the sheet is disclosed. Methods of implantation of the implants are disclosed.

Abstract: A method of providing neuromodulation treatment to a patient includes both an assessment procedure prior to the application of magnetic stimulation signal to the patient during a treatment period of time. The assessment procedure is completed prior to the treatment period of time and senses an electroencephalogram (EEG) signal of the person and then an evaluates the EEG signal to obtain a measure of a patient's endogenous brain activity within a selected EEG band of the EEG signal of the patient. A control subsystem adjusts a stimulation protocol parameter used in the generation of the magnetic stimulation signal based upon the measure of a characteristic of the patient's endogenous brain activity obtained during the assessment procedure. The adjusted magnetic signal is then applied to the head of the patient for providing treatment to the patient patient's brain.

Abstract: Systems and method for destroying or inhibiting cancer cells and other rapidly-dividing cells include applying AP magnetic fields having a defined frequency of 5 Hz-500 kHz and a field strength of 0.1-5000 ?T to a target body area that includes the cancer or other rapidly-dividing cells, and modifying the cancer or tumor microenvironment to increase the presence of cancer-suppressive cells or decrease the presence of cancer-promoting cells. In various embodiments, the systems and methods may include adjusting the therapy based on the dosage of an immunotherapy drug administered to the patient before, during, or after the application of the AP magnetic fields.

Abstract: A method for assessing neurological function in a subject includes a) prompting a user to follow a moving saccade-evoking stimulus on a display, b) tracking eye movement of the subject while the user follows the moving stimulus, c) collecting a first eye conjugacy data of the subject relating to the saccade-evoking stimulus, and d) comparing the first eye conjugacy data with a second eye conjugacy data, the second eye conjugacy data relating to an anti-saccade stimulus.

Abstract: An instrument sterile adapter couples a surgical instrument and an instrument carriage. The instrument sterile adapter includes an instrument plate that provides a first surface to receive the surgical instrument and a latch plate joined to the instrument plate. The latch plate includes a second surface to receive the instrument carriage and latch structures. Each latch structure has a carriage latch arm that extends away from the second surface of the latch plate and an instrument latch arm joined to the carriage latch arm. The instrument latch arm extends through the instrument plate and away from the first surface of the instrument plate. A connecting member flexibly connects the carriage latch arm and the instrument latch arm to a remainder of the latch plate. The connecting member may be perpendicular to the latch arms. The latch arms may engage fixed locking surfaces in the instrument carriage and the surgical instrument.

Abstract: Wearable devices can be used to provide therapy to users and/or to monitor various physiological parameters of the user. In some cases, therapy can be triggered automatically based on the monitored physiological parameters reaching or exceeding predefined thresholds.

Abstract: Described is a catheter for being retained inside the body for extended periods, and a catheter mating device that can connect to the catheter to move the catheter inside of the body or remove it from the body. The catheter mating device has a stem with an apparatus at its distal end. The apparatus is moveable between a first position and a second position. When in its first position, the distal end is configured to fit in the proximal end of the catheter. When in its second position, the distal end engages the proximal end of the catheter and connects the catheter mating device to the catheter.

Abstract: Distributed feedback-circuitry uses operant conditioning to train a subject to achieve a target state of consciousness. The distributed feedback-circuitry includes remote circuitry having both a feature-extraction circuit and a controller. The former receives a real-time electroencephalogram and information indicative of a target state from the subject and generates a measured feature-set and a target feature-set therefrom. The latter causes transmission of a conditioning stimulus to be listened to by the subject. The conditioning stimulus causes the measured feature-set to be driven towards the target feature-set. The controller also causes the conditioning stimulus to comprise a conditioning-audio stimulus that transitions between being a base-audio stimulus with no reward stimulus and being a base-audio stimulus that has been operated on to incorporate a reward stimulus. The controller causes this transition based on progress made in causing the measured feature-set to conform to the target feature-set.

Abstract: Systems for destroying or inhibiting cancer cells and other rapidly-dividing cells including an alternating polarity (AP) magnetic field generator and at least one AP electromagnetic coil adapted to be coupled to a target body area, and a controller to control the AP magnetic field generator and at least one AP electromagnetic coil and cause the field generator and coil to apply AP magnetic field having a frequency of 0.5-500 kHz and a field strength of 0.5-5 mT to the target body area to achieve a desired inhibiting effect on cancer cells or other rapidly-dividing cells. Treatments provided by the system may be co-administered with an anti-cancer drug such as a chemotherapy drug, a hormone therapy drug, targeted therapy drugs, immunotherapy drugs, or an angiogenesis inhibitor drug.

Abstract: A method for detecting the tendency of a passenger of a vehicle to get motion sickness by using a rod and frame test is disclosed. An image designed to carry out a rod and frame test is displayed in the vehicle. The rod and the frame each enclose an angle greater than 0 degrees and less than 90 degrees with a horizontal spatial axis and/or a vertical spatial axis. A request is issued to correct the rod into a vertical or horizontal position by means of an input device. An input carried out by the passenger to correct the rod is recorded. The rod and frame test is evaluated by an evaluation device based on the recorded input of the passenger, and at least one measure is issued to prevent and/or combat the occurrence of motion sickness, depending on the result of the evaluation.