Abstract: Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms.

Abstract: A blood pressure measurement device having an attach portion including: an opening portion provided at a position opposite a region where one artery of a wrist is found and an end surface that curves conforming to a shape in a circumferential direction of a portion of the wrist; a fastener on the attach portion; and a sensing body including: a sensor unit opposite the opening portion, the sensor unit including a sensor module that comes into contact with the region where the one artery of the wrist is found and an air bag that presses the sensor module toward the wrist by expanding when the device is worn on the wrist, a case that houses the sensor module to allow the sensor module to move in one direction with respect to the opening portion, and a biasing member that biases the sensor module in a direction away from the wrist.

Abstract: An acoustic sensor attached to a medical patient can non-invasively detect acoustic vibrations indicative of physiological parameters of the medical patient and produce an acoustic signal corresponding to the acoustic vibrations. The acoustic signal can be integrated one or more times with respect to time, and a physiological monitoring system can determine pulse or respiration parameters based on the integrated acoustic signal. The physiological monitoring system can, for instance, estimate a pulse rate according to pulses in the integrated acoustic signal and a respiration rate according to a modulation of the integrated acoustic signal, among other parameters. Further, the physiological monitoring system can compare the integrated acoustic signal or parameters determined based on the integrated acoustic signal with other signals or parameters to activate alarms.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Abstract: A real-time motion capture system and garment includes a wearable activity monitor that may be a pair of denim jeans. The wearable activity monitor includes multiple sensors such as accelerometers, gyrometers, magnetometers disposed within the seams of the garment. A microprocessor and wireless transmitter) communicate the motion data to an external device. The microprocessor and wireless transmitter may be included within one of the seams. An elastically stretchable ribbon or a flexible ribbon such as a kapton ribbon or a ribbon formed of textile, electrically couples the sensors and microprocessor and is also disposed inside the seams and the components within the seam are coated with a waterproof coating. The external device can store the data or display and analyze the data real-time, and may communicate the data to a further electronic device.

Abstract: A positioning method of functional rotation center of shoulder based on rigid upper arm model includes: step 1: abstracting a human upper arm into a cylinder with FRCS as a center of top surface; step 2: determining a reference axis vector of the cylinder; step 3: determining an axis vector of the cylinder and a displacement from the reference axis vector to the axis vector; step 4: correcting a central axis direction of the cylinder; step 5: determining a height compensation of the cylinder, and positioning the FRCS. The method has higher accuracy for the positioning result of FRCS, the positioning result of FRCS has better stability relative to the upper arm and trunk, and can be used to establish a more accurate human digital dynamic model and predict more accurate human posture.

Abstract: The present invention relates to a brain dysfunction and seizure detector monitor and system, and a method of detecting brain dysfunction and/or seizure of a subject. Preferably, the present invention also includes one or more seizure detection algorithms. The analysis method is specifically optimized to amplify abnormal brain activity and minimize normal background activity yielding a seizure index directly related to the current presence of ictal activity in the signal. Additionally, a seizure probability index based on historical values of the aforementioned seizure index, is derived for diagnostic purposes. The seizure probability index quantifies the probability that the patient has exhibited abnormal brain activity since the beginning of the recording. These indexes can be used in the context of emergency and/or clinical situations to assess the status and well-being of a patient's brain, or can be used to automatically administer treatment to stop the seizure before clinical signs appear.

Abstract: An electrocardiogram measurement system includes a patch-type electrocardiogram measurement apparatus; a first device connected to the electrocardiogram measurement apparatus by means of a first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus; and a second device connected to the electrocardiogram measurement apparatus by means of the first communication and configured to store electrocardiogram data measured by the electrocardiogram measurement apparatus. The electrocardiogram data measured by the electrocardiogram measurement apparatus includes measured time information.

Abstract: Methods, systems, and devices for measuring respiratory parameters from an ECG device are described. The method may include receiving an electrocardiogram (ECG) signal associated with a patient. The method may further include detecting a change in modulation of the ECG signal between a first portion of the ECG signal and a second portion of the ECG signal. The method may further include determining a change in respiratory effort of the patient based at least in part on the change in modulation.

Abstract: Bending stresses experienced by a pressure sensor mounted to a fractional flow reserve catheter when tracking the catheter through the vasculature creates a distortion of the sensor resulting in an incorrect pressure reading or bend error. In order to isolate the sensor from bending stresses, the sensor is mounted with one end coupled to the distal end of the shaft while the other end of the sensor is not coupled to the catheter so that a portion of the sensor is spaced apart from the distal end of the shaft.

Abstract: This invention is a dry EEG electrode with an articulated distal base and/or a plurality of articulated conductive proximal protrusions which penetrate between strands of hair for good electromagnetic contact without causing discomfort or skin irritation.

Abstract: Sensor delivery devices and methods of measuring Fractional Flow Reserve in a patient are disclosed. One sensor delivery device includes a distal sleeve, a proximal portion, and a pressure sensor. The distal sleeve is configured to be advanced through a patient's vasculature over a guidewire. The pressure sensor is located on the distal sleeve or the proximal portion. The pressure sensor is adapted to generate a signal proportional to fluid pressure. The pressure sensor includes a material having a low thermal coefficient of pressure.

Abstract: An impedance-based respiration monitoring system for apnea detection includes at least three surface electrodes configured to record impedance respiration data from a patient's torso, a signal processing system, and an apnea detection module. The signal processing system is configured to generate a first respiration lead formed by a first set of surface electrodes from the at least three surface electrodes, the first respiration lead providing a first series of impedance measurements, and to generate a second respiration lead formed by a second set of surface electrodes attached to the patient's torso, the second lead providing a second series of impedance measurements. The apnea detection module is executable on a processor to calculate a first apnea metric based on the first series of impedance measurements, and calculate a second apnea metric based on the second series of impedance measurements. An apnea event is then detected based on the first apnea metric and the second apnea metric.

Abstract: Embodiments herein include testing articles to assess hydration of a test subject. The testing articles can include a carrier portion having a porous medium through which a fluid of the test subject moves. The carrier portion can include a first end and a second end opposite the first end. The testing articles can include a first chemical composition disposed in the porous medium that reacts with chloride ions to produce a first color change. The testing articles can include a wick that is in direct contact with the first end of the carrier portion to allow the transfer of the fluid from the wick to the carrier portion. The testing articles can include a fill indicator element in direct contact with the second end of the carrier portion to allow the transfer of the fluid from the carrier portion to the fill indicator element. Other embodiments are also included herein.

Abstract: Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein.

Abstract: In a biopotential-physiological-phenomena sensing system, an impedance measurement circuit for measuring the impedance of a channel electrode that is applied to a subject's body for sensing a physiological phenomenon includes: an amplifier, a DC-biased power supply with an AC component and a conductive element. The amplifier has a signal input coupled to a channel electrode that is applied to a subject's body and a signal output for providing an output voltage that is representative of a voltage provided at the signal input in accordance with an amplification of the amplifier. The conductive element is coupled between the power supply and the signal input of the amplifier. The AC component of the DC-biased power supply causes a known test current to flow through the channel electrode thereby causing a voltage drop proportional to the impedance of the channel electrode at the input of the amplifier. The impedance of the channel electrode is measured in accordance with the amplifier's output voltage.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: A two part patient monitoring device includes an activator module and a sensor device. The activator module includes a non-galvanic data port that creates a communication path with a non-galvanic data port on the sensor device. The activator module includes power contact pads that are each at least partially surrounded by a bias ring. A bias voltage is applied to the bias rings and a processor or circuit in the activator module monitors the voltage on the bias ring to detect a leakage current. The sensor module includes power contact pins that engage the power contact pads to transfer power from the activator module to the sensor device. Each of the contact pins are surrounded by a seal member such that the connection between the power contact pins and the power contact pads is protected from debris and/or moisture.

Abstract: This invention is a system for nutritional monitoring and management which includes a camera, a spectroscopic sensor, a fiducial component, a wearable biometric sensor, a smart utensil or dish, a passive feedback mechanism which provides a person with information concerning food item types and/or quantities, and an active stimulus mechanism which modifies the person's food-related physiological processes. This system can help a person to improve their dietary habits and health.

Abstract: This disclosure relates to a glucose-sensing electrode including a nanoporous layer on an electrically conductive surface. The nanoporous layer includes a three-dimensional interconnected network of irregularly shaped bodies that are formed of numerous nanoparticles having a generally oval or spherical shape with a length ranging between about 2 nm and about 5 nm. Inside the three-dimensional interconnected network of irregularly shaped bodies, at least part of the nanoparticles are adjacent to each other without an intervening nanoparticle therebetween and apart from each other to define interparticular nanopores therebetween, wherein at least part of the interparticular nanopores inside the three-dimensional interconnected network of irregularly shaped bodies are in a size ranging between about 0.5 nm and about 3 nm.