Abstract: The invention relates to benzoylcyclohexenone derivatives of general formula (I) wherein the variables R1 to R10 and n have the designation cited in claim 1.
Type:
Grant
Filed:
July 26, 2002
Date of Patent:
March 27, 2007
Assignee:
BASF Aktiengesellschaft
Inventors:
Wolfgang von Deyn, Ernst Baumann, Michael Hofmann, Markus Kordes, Ulf Misslitz, Liliana Parra Rapado, Cyrill Zagar, Matthias Witschel, Andreas Landes
Abstract: Arylamine derivatives that can be utilized as hole transport or hole injection materials of organic electroluminescence devices, electrophotographic reactors, etc., and synthetic intermediates thereof, and processes of producing those. The arylamine derivative is represented by the general formula (1): wherein R1 to R4 each independently represents a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, an aryloxy group, a halogen atom, an amino group, etc.; Ar1 and Ar2 each independently represents a substituted or unsubstituted aryl group or hetero-aromatic group, and Ar1 and Ar2 may form a nitrogen-containing heterocyclic ring together with the nitrogen atom to which Ar1 and Ar2 bond; and Ar3 represents a substituted or unsubstituted arylene group.
Abstract: Clogging of a distillation column by polymerization caused by a change of the production rate of (meth)acrylic acid, is prevented to carry out a stabilized operation over a long period. A process for producing (meth)acrylic acid, which includes a purification step wherein a (meth)acrylic acid-containing material to be purified is supplied to and distilled by a distillation column, wherein during a cut operation in which the production rate of (meth)acrylic acid is reduced by ?% relative to the production rate of (meth)acrylic acid during the ordinary operation, the liquid/gas flow rate in the distillation column is adjusted to be at least (100??/2)% of the liquid/gas flow rate during the ordinary operation.
Abstract: Disclosed in one embodiment is a process for the synthesis of 1,3,3,3-tetrafluoropropene that comprises (a) reacting a compound of formula (I) X1X2 with a compound of formula (II) CF3CH?CH2 to produce a reaction product comprising a compound of formula (III) CF3CHX1CH2X2, wherein X1 and X2 are each independently selected from the group consisting of hydrogen, chlorine, bromine and iodine, provided that X1 and X2 are not both hydrogen; (b) when X2 in formula (III) is not fluorine, fluorinating the compound of formula (III) to produce a reaction product comprising a compound of formula (III) wherein X1 is as described above and X2 is fluorine; and (c) exposing said compound of formula (III) to reaction conditions effective to convert said compound to 1,3,3,3-tetrafluoropropene.
Type:
Grant
Filed:
April 29, 2005
Date of Patent:
March 13, 2007
Assignee:
Honeywell International
Inventors:
Sudip Mukhopadhyay, Haridasan K. Nair, HsuehSung Tung, Michael Van Der Puy
Abstract: The present invention relates to a process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives of the formula I, which are valuable pharmaceutical active ingredients and can be used, for example, as antidepressants. The process starts from O-ethyl phosphinates of the formula II into which, after silylation with hexamethyldisilazane, the 3-amino-2-hydroxypropyl moiety is introduced by reactions with epichlorohydrin and ammonia.
Abstract: The invention relates to reaction products of glycols, diglycols, higher glycols or glycerol with ?-hydroxycarboxylic acids in a molar ratio of 1:2 or higher, especially conforming to the general formula (V) where R is hydrogen or a C1-3 alkyl group, preferably methyl, nx is from 1 to 5, preferably from 1 to 3, n is 1 or 2 and when n=1 the radical R? is C1-4 alkylene, preferably ethylene, x is defined as x? and y is not less than 1, preferably from 1 to 5, especially 1 or 2, and when n=2 the radical R? is a glycerol radical, x is defined as x? and y is =1. The invention further relates to the use of the (poly)hydroxycarboxylic acid (poly)glycol esters or (poly)hydroxycarboxylic acid glyceryl esters as acid donors and for controlling the pH in textile treatment processes.
Abstract: The present invention relates to a method for increasing the heat-resistant of ethylene-vinyl alcohol copolymer (EVOH), the method is characterized by using a mixture of acetic acid, magnesium dihydrogen phosphate, and potassium dihydrogen phosphate at a certain ratio as an acid-treating solution in the acid-treating procedure of a process for preparing EVOH. The EVOH produced by the method of the present invention exhibits an excellent heat-resistance and does not become yellowing attributed to the elevated processing temperature. Also, the EVOH generated by the method of the present invention exhibits a uniform heat-resistance since the additives are dispersed evenly in the EVOH.
Type:
Grant
Filed:
June 20, 2003
Date of Patent:
March 6, 2007
Assignee:
Chang Chun Petrochemical Co., Ltd.
Inventors:
Jing Jin Tsai, Li Shing Lin, Huan Ming Chang, Kuang Hui Fan, Weng Shing Lin
Abstract: A compound of Formula (IA) or Formula (IB) wherein R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
Type:
Grant
Filed:
May 28, 2003
Date of Patent:
March 6, 2007
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
Inventors:
Thomas Martin Kirrane, Jr., Daniel Kuzmich, John Robert Proudfoot, David Thomson
Abstract: The present invention relates to triphenylene compounds useful, for example, in an electrophotographic photoreceptor, and to a method for manufacturing these compounds.
Abstract: The invention relates to the polymorph A of flibanserin, to a technical process for the preparation thereof, as well as to the use thereof for preparing medicaments.
Type:
Grant
Filed:
August 1, 2002
Date of Patent:
February 27, 2007
Assignee:
Bidachem S.p.A.
Inventors:
Carlo Bombarda, Enrica Dubini, Antoine Ezhaya, Margarete Schneider, legal representative, Heinrich Schneider, deceased
Abstract: Process for removal of the esterification catalyst by separation from a crude plasticizer ester obtained by reacting a dicarboxylic acid with C8–C13 alcohols, by treating the crude ester with an aqueous alkali solution in the range from 10 to 100° C. and then separating the aqueous alkaline phase comprising the hydrolyzed esterification catalyst by gravitational phase separation, by treating the crude ester, prior to or during the phase separation, with a salt of a di- or polyvalent metal, or with a mixture of these salts.
Type:
Grant
Filed:
July 23, 2003
Date of Patent:
February 27, 2007
Assignee:
BASF Aktiengesellschaft
Inventors:
Kurt Schwirten, Walter Disteldorf, Günther Golfier, Jarren Peters
Abstract: Process for obtaining a hydrofluoroalkane which is purified of organic impurities, according to which the hydrofluoroalkane containing organic impurities is subjected to at least one purification treatment chosen from (a) a treatment with chlorine in the presence of a initiator (b) a reaction with hydrogen fluoride (c) a distillation in which the purified hydrofluoroalkane is removed from the top of the distillation column or from the side (d) an extractive distillation (e) an adsorption onto a solid adsorbent (f) a reaction with a compound containing oxygen, and (g) a reaction with a compound containing oxygen and a gas-phase reaction with a reagent capable of reacting with at least some of the organic impurities, with the exception of a reaction with elemental chlorine.
Type:
Grant
Filed:
August 10, 2001
Date of Patent:
February 20, 2007
Assignee:
Solvay (Societe Anonyme)
Inventors:
Vincent Wilmet, Francine Janssens, Lionel Casaubon Seignour, Philippe Krafft, Alain Lambert, Olivier Buyle
Abstract: Organohalosilanes are prepared by reacting metallic silicon particles with an organohalide in the presence of a copper catalyst. A contact mass composed of the metallic silicon and the copper catalyst contains an effective amount of a catalyst alloy containing 0.2–8 wt % of tin and 4–20 wt % of phosphorus which is powdered by atomization.
Abstract: The invention concerns (aryl)(amino)borane compounds and a method for preparing same. Said compounds are of formula A-BH—NR1R2, wherein: R1 and R2 are selected among linear, branched or cyclic alkyl radicals, and arylalkyl radicals, or R1 and R2 form together an alkylene; and A represents an aromatic or heteroaromatic group optionally polycondensed, or a group selected among the vinyl, dienyl, polyenyl and alkynyl groups, all said groups optionally bearing at least one substituent. The compounds are obtained by a method which consists in preparing an amine-borane R1R2NH.BH3 complex, in transforming it into aminoborane R1R2NBH2 by heating, then in reacting it with an A-X compound wherein X is a leaving group.
Type:
Grant
Filed:
December 20, 2002
Date of Patent:
February 20, 2007
Assignees:
Centre National de la Recherche Scientifique, Universite de Rennes
Abstract: The invention relates to the use of derivatives of cyclopentenone for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing such compounds. The invention relates more specifically to the use of derivatives of cyclopentenone for the inhibition and/or prevention of cancer of the colon, pancreas, larynx, ovary, duodenum, kidney, oral cavity, prostate, lung, endothelial cells and leukemias.
Type:
Grant
Filed:
December 4, 2002
Date of Patent:
February 20, 2007
Assignee:
Dabur Research Foundation
Inventors:
Mukund K. Gurjar, Radhika D. Wakharkar, Gautam R. Desiraju, Ashwini Nangia, Jhillu Singh Yadav, Anand C. Burman, Rama Mukherjee, Hanumant Bapu Rao Borate, Srivari Chandrasekhar, Manu Jaggi, Anuo T. Singh, Kamal Kapoor, Sanjay Sarkhel, K. V. V. M. Sairam
Abstract: An improved process for recovering a crystalline product (particularly an N-(phosphonomethyl)glycine product) from a solution comprising both a product subject to crystallization and undesired impurities is provided.
Type:
Grant
Filed:
September 17, 2004
Date of Patent:
February 20, 2007
Assignee:
Monsanto Technology LLC
Inventors:
Eric A. Haupfear, Eduardo A. Casanova, Kenneth S. Meyer, Henry H. Chien
Abstract: A process is provided for preparing a sodium ferric gluconate complex, substantially free of excipients, for providing a sodium ferric gluconate complex co-precipitated with sucrose, and for providing sodium ferric gluconate complexes in aqueous solution.
Type:
Grant
Filed:
July 12, 2004
Date of Patent:
February 20, 2007
Assignee:
Navinta LLC
Inventors:
Jagadeesh Babu Rangisetty, Christopher Benny Newton
Abstract: The methods of preparing quinols and quinones typified by mitoquinol and mitoquinone where a compound typified by idebenone is reacted with Ph3PHX and Ph3P, where X is a halogen atom.
Type:
Grant
Filed:
August 12, 2002
Date of Patent:
February 20, 2007
Assignee:
Antipodean Pharmaceuticals, Inc.
Inventors:
Robin Andrew James Smith, Michael Patrick Murphy
Abstract: Disclosed is a method for producing Alkyllithium compounds by reacting metallic lithium with an Alkyl halide in a solvent. The reaction is performed at a reduced pressure at the boiling point of the solvent.