Abstract: An endotracheal tube holder secures an endotracheal tube in a selected position within the patient's mouth and trachea and includes a tube holding block having an elongated cradle that extends inwardly of a patient's mouth. The holding block is formed having a tube clasp housing in which is located a plurality of tube securing pins, whereby the endotracheal tube is held in place by the securing pins and a pair of oppositely disposed flexible flange members which engage and hold the tube in a substantially fixed position with respect to the patient's mouth, and wherein a flexible biting block is interposed between the tube cradle and the tube clasp housing.