Abstract: An insertion tool for implanting a medicinal delivery device, such as which is attached to the tissue or mucous membrane lining of a human organ, such as a female cervix, through a variety of means not limited to vacuum suction and/or mechanical fastening. The delivery tool exhibits an elongated body with a vacuum inducing support surface for retaining the delivery device in a first implantation stage. Forward end located actuating clamps grip peripheral locations of the device during implantation, and upon completion, can be pivoted out of engagement with the body of the delivery device, via the toggle initiated displacement of a sleeve integrated into the elongated body.

Abstract: The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel contents thereof.

Abstract: An orifice-free drug delivery device is provided. In an embodiment, the device includes a body having at least one water-permeable wall bounding a reservoir defined within the body. A drug formulation is disposed within the reservoir. The body has an elastic portion and at least one restraining plug closing off an opening of the body. The opening is in fluid communication with the reservoir, and the restraining plug contacts the elastic portion of the body and controls release of the drug from the device by the transient formation of one or more microchannels between the elastic portion of the body and the at least one restraining plug. The elastic portion may define an opening having an inner diameter, which is exceeded by the outer diameter of the restraining plug by at least 3%.

Abstract: Embodiments disclosed herein are directed to systems and methods for protecting needleless injector units from one or more contaminants. In an embodiment, a needleless injector system includes a needleless injector unit and an auxiliary unit. The needleless injector unit has a nozzle portion and a supply of one or more substances for injection. The needleless injector unit is configured to inject the one or more substances from the nozzle portion through a skin surface of a subject. The auxiliary unit is coupleable to the needleless injector unit. The auxiliary unit includes a source of one or more protectants and is configured to emit the one or more protectants in a region between the nozzle portion of the needleless injector unit and the skin surface of the subject.

Abstract: There is provided a therapeutic instrument, for storing a sheet-type therapeutic substance to which a liquid is delivered, and delivering the stored therapeutic substance to an affected part, including: a nozzle member 23 having an opening 34 on a tip end of a tubular part 31 in which the therapeutic substance can be stored, for charging and discharging the therapeutic substance; and a syringe unit 22 that selectively causes a negative pressure and a positive pressure to act in the tubular part 31 through a hole of a valve member 27, wherein the space 33 of the tubular part 31 is the space for sucking the therapeutic substance into the tubular part 31 together with the liquid by causing the negative pressure in the tubular part 31 by the syringe unit 22 when the therapeutic substance is stored therein, and is the space for pushing out the therapeutic substance to outside of the tubular part 31 together with the liquid by causing the positive pressure to act in the tubular part 31 by the syringe unit 22 when t

Abstract: A tension mechanism for a robotically-controlled medical device measures the tension applied to an actuation tendon to provide feedback to a robotic controller. In one embodiment, the device comprises an elongated instrument, an elongated member, and a base. The elongated member is coupled to the distal end of the elongated instrument, configured to actuate the distal end of the elongated instrument in response to tension in the elongated member. The base is located at the proximal end of the elongated instrument, and comprises a first redirect surface that redirects the elongated member. The first redirect surface is coupled to a lever element that is configured to exert a reactive force on a sensor in response to tension in the elongated member.

Abstract: A device to administer multiple capsules or pills or a combination of capsules or pills into the mouth of an animal. The device is gravity fed and is composed of seven parts. The parts are: (i) a molded tee handle, (ii) a molded trigger pin (tee handle), (iii) a spring pin (trigger release pin) which is part of the molded trigger; (iv) a torsion spring; (v) a tube which can be 6 inches long with an outer diameter such as ½ inch with varying inner diameters resulting from different interior thicknesses of the barrel; (vi) a ? inch ID #4 pan head screw; and (vii) a ? inch diameter disc.

Abstract: This invention is a continuous monitor of the spinal cord and brain microenvironment in injury and disease that also allows therapeutic interventions. It utilizes a multiport catheter that contains a transducer at the tip for monitoring spinal physiological parameters and also allows via additional ports for sampling and exchange of spinal fluid, as well as drug delivery to the central nervous system. This invention allows for more precise therapeutic interventions in spinal cord and brain injury and disease. If the pressure monitor is mounted to the patient, the wireless data transmitter may also send a wireless signal to a wireless data receiver for display on a wireless data display. The catheter would allow for wireless transmission of physiological parameters.

Abstract: An access device places a medical article within a body space of a patient. The device has a needle that includes an elongated body and a needle hub. The device further includes a dilator disposed on and slideable along the elongated body of the needle and a medical article. The medical article is disposed on and slideable along the dilator. A track extends in a proximal direction from the dilator. The needle hub slides along at least a portion of the track between a first position and a second position. The device further includes a locking mechanism operably disposed between the track and the needle hub so as to inhibit further axial movement of the needle in the proximal direction when the needle hub is in the second position.

Abstract: A disposable skin-worn device for the transdermal delivery at least one dose of charged therapeutic substances, including granisetron, by iontophoresis, the device comprising a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, a counter reservoir, a source of electric power connected in a circuit between the donor reservoir and the counter reservoir and a control system for controlling current flow in the circuit to enable at least one dose of the therapeutic substance to be delivered transdermally by iontophoresis and wherein the control system includes a control element selected from the group consisting of a sensor activated by an external signal and a switch.

Abstract: The dispensing device includes a hollow tube having an open upper end and an open lower end, as well as a horizontal bar disposed between the walls of the hollow tube adjacent to the open lower end. A disc is movably positioned within the hollow tube, the disc having a central aperture defined therein. A string or other flexible member has one end secured to the disc. The other end of the string is drawn downward in the tube, looped around the horizontal bar, then drawn upward through the central aperture in the disc and out the open upper end of the tube. A semi-solid medication is loaded in the tube between the disc and the open lower end of the tube. When the string is pulled out of the upper end of the tube, the disc is drawn downward, dispensing the medication.

Abstract: Drive and metering devices for injection devices include a dose display element with a helical dosage scale; an indicating means; a metering member, which can be rotated relative to the indicating means for dose setting; a discharge spring and an advancement member. The dose display element can be screwed relative to the indicating means about a longitudinal axis (L) and a value on the dose scale can be read via the indicating means corresponding to the set dose. The discharge spring causes the advancement member to discharge the product as it moves an overall discharge stroke length (Hg), where the overall discharge stroke length (Hg) comprises a first partial discharge stroke length (H1), during which the dose display element is rotationally secured in relation to the indicating means and where the dose display element can be rotated relative to the indicating means following the first partial discharge stroke length (H1).

Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

Abstract: The present invention relates in one aspect to an infusion fluid warmer which comprises a casing shell having an upper wall structure and a lower, opposing, wall structure. The casing shell encloses a fluid channel or passage extending through the casing shell in-between the upper and lower wall structures and fluid inlet and outlet ports coupled to opposite ends of the fluid channel or passage to allow a flow of infusion fluid through the casing shell. A housing shell is formed in a thermally conducting and electrically insulating material and a heating element is bonded to the housing shell and thermally coupled thereto. The fluid channel or passage extends through the housing shell or extends around the housing shell such that heat energy is transferred to the infusion fluid by direct physical contact with housing shell material.

Abstract: A medical injector is provided herein having a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided formed to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally towards a distal end of the body but not proximally towards a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger thereby allowing the engagement portion to by-pass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector.

Abstract: A needleless fluid delivery system for delivering therapeutic fluids to treatment sites within a patient. The fluid delivery system can include an automated injector source and a needleless access device. The access device can include a delivery scope and a treatment specific applicator. The automated injector source, delivery scope and applicator can be operably coupled with quick-connect style fittings so as to allow for quick replacement and maintenance of used or damaged components. The automated injector source can include a hands-free input mechanism allowing a medical professional to use both hands in manipulating the delivery scope and needleless applicator at the same time an injection is desired. The delivery scope and needleless applicator can comprise flexible or rigid lengths of tubing based on the accessibility of the treatment site. The needleless delivery system can include an imaging system for precisely position the applicator with respect to the treatment location.

Abstract: An auto-injector device including a syringe, a needle arranged in the vicinity of a first end of the syringe, and a plunger arranged within the syringe. A volume within the syringe between the plunger the needle accommodates medicine, such that movement of the plunger toward the needle dispenses medicine through the needle. A selection assembly configurable by a user to adjust an amount of medicine dispensed by the auto-injector device and depth to which the medicine is delivered. Also, a method for treating a skin lesion or skin disorder utilizing the auto-injector and a kit for patient administered treatment.

Abstract: Described is a needle assembly attachment and removal device comprising a case having a base and a longitudinal axis (L), a carriage axially movable with the case from a first position to a second position, a carrier rotatably coupled to the carriage and adapted to hold a needle assembly, and a gearing arrangement rotatably coupled to the carriage and adapted to rotate the carrier in a first rotational direction as the carriage moves from the first position to the second position and in a second rotational direction as the carriage moves from the second position to the first position.

Abstract: An autoinjector including a housing, in which can be mounted a syringe having a plunger, a barrel and needle at one end thereof through which medicament can be delivered to an injection site; a syringe support means capable of causing said syringe to move therewith along an axial path with respect to said housing; biasing means capable of biasing said syringe support means so that said needle is normally inside said housing, blocking means selectively moveable by a user from a first position in which rearward movement of the syringe along said axial path is substantially prevented, to a second position in which rearward movement of the syringe along said axial path relative to said housing is possible and said biasing means causes said needle to retract inside said housing.

Abstract: Systems and methods for nasal irrigation are provided in which a nasal irrigation device includes a source of saline, an effluent receptacle, a nasal interface, a vacuum source, a fluid passageway to communicate the source of saline with the effluent receptacle through the nasal interface and a nasal cavity of the user, and a switch and valve assembly for selectively controlling the vacuum source and flow of the saline through the fluid passageway. The saline source is disposed relative to the device to provide gravitational inducement of saline to the nasal interface in engagement to the device user's nostrils. A combination of the gravitational inducement and the relative vacuum from the effluent receptacle generates a fluid flow for irrigating, cleansing and massaging the nasal cavity and ostia of the user. The entire device is assembled as a hand-held device for convenient lifting and disposal against the user's nostrils.