Abstract: A method and apparatus are provided for the stimulation through the sphenoid sinus, the pituitary gland and the adjoining brain structures. The apparatus consists of an inflatable balloon and which is inserted into the sphenoid sinus and inflated. The balloon will stimulate by pressure, heat, cold or electricity, the structures surrounding the sphenoid sinus. The balloon is controlled via connecting tubes and control wires. This method and apparatus has application in the treatment of pain and a number of other maladies of the nervous system.