Patents Examined by Y Pak
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6537788
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 25, 2003
    Assignee: Applera Corporation
    Inventors: Jane Ye, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
  • Mutant 1,3-propandiol dehydrogenase
    Patent number: 6468773
    Abstract: The present invention relates to mutant 1,3-propanediol dehydrogenase and a novel microorganism that is capable of growing in concentrations of at least 105 g/l 1,3-propanediol, levels normally toxic to wild-type microorganisms. The present invention also provides expression vectors and host cells comprising the mutant 1,3-propanediol dehydrogenase as well as methods for producing 1,3-propanediol comprising the use of cells comprising the mutant 1,3-propanediol dehydrogenase.
    Type: Grant
    Filed: May 14, 2000
    Date of Patent: October 22, 2002
    Assignee: Genencor International, Inc.
    Inventors: Trimbur E. Donald, Whited M. Gregory, Olga V. Selifonova
  • Genes encoding picric acid degradation
    Patent number: 6461856
    Abstract: A 12 kb gene cluster has been isolated from Rhodococcus erythropolis containing several open reading frames implicated in the degradation of picric acid. The gene cluster contains 12 ORF's, all of which were isolated by a method employing differential gene display.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: October 8, 2002
    Assignee: E. I. du Pont de Nemours & Company
    Inventors: Pierre E. Rouviere, Dana M. Walters, Rainer Russ
  • Human nucleic acid methylases
    Patent number: 6436683
    Abstract: The invention provides a human nucleic acid methylases (HNAM) and polynucleotides which identify and encode HNAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HNAM.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: August 20, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Karl J. Guegler, Henry Yue
  • Regulation of quinolate phosphoribosyl transferase expression
    Patent number: 6423520
    Abstract: DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided.
    Type: Grant
    Filed: October 29, 1999
    Date of Patent: July 23, 2002
    Assignee: North Carolina State University
    Inventors: Mark A. Conkling, Wen Song, Nandini Mendu
  • Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
    Patent number: 6323016
    Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: November 27, 2001
    Assignee: PE Corporation (NY)
    Inventors: Jane Ye, Karen A. Ketchum, Valentine Di Francesco, Ellen M. Beasley