Abstract: Automation for a system and/or method detects and/or controls treatment of inspiratory flow limitation. The system may include a flow rate sensor configured to generate a signal representing a respiratory flow rate of a patient. It may include a recording device configured to record the generated respiratory flow rate signal during a diagnosis session. It may include a computing device (7040) configured to detect a degree of inspiratory flow limitation of the patient on the recorded respiratory flow rate signal. The method may include extracting an inspiratory portion of each breath during a detection and/or monitoring session from a respiratory flow rate signal of the patient, calculating a feature vector from each inspiratory flow portion, labelling each feature vector as flow limited or not flow limited, and/or computing a metric based on the labels, the metric indicating the degree of inspiratory flow limitation of the patient during the session.

Abstract: Apparatuses and methods of using them to collect blood, are provided, by first ensuring that the patient's skin is properly cleaned, to prevent contamination of the collected blood. One feature is a blood collection device configured to collect blood from a patient. Another feature is a scrub timer integrated into the device and configured to indicate to a user a scrub time period prior to beginning a blood draw process. The scrub timer can be configured to audibly and/or visually indicate to a user the start and stop times of a scrub cleaning process. In one embodiment, the scrub timer can be restarted, either manually or automatically, if the scrub cleaning process is not followed properly.

Abstract: A patient treatment unit and method analyzes and treats pain in tissues by applying an electrical pulse train to the affected tissue. The impedance of the affected tissue is measured, and the measured impedance is correlated to a level of pain in the patient. The pulse train is further applied in response to the measured impedance to reduce the patient's pain. The patient treatment unit includes a probe stimulus generator that outputs the pulse train. The treatment unit also includes a pair of probes for contacting the patient's body and receiving the pulse train. The pulse has improved shaping based on isolation of high voltage from a low voltage control. The unit further includes a body impedance analysis circuit that senses voltage and current via the probes when the probes are contacting the patient and observe the impedance. A monitor is electrically coupled to the body impedance analysis circuit and provides an indication of the measured impedance indicative of the patient's level of pain in real-time.

Abstract: The application discloses a method for monitoring a user gesture and a wearable device. The method comprises: providing an inertial sensor in a wearable device, the wearable device being located on the head of a user when being worn; monitoring movement data of the head of the user in real time, by using the inertial sensor, when the user is wearing the wearable device; conducting gesture solving by using the movement data to obtain gesture data of the head of the user; determining whether a head gesture of the user is a correct gesture according to the gesture data and a preset strategy; and sending a reminder to the user when the head gesture of the user is an incorrect gesture.

Abstract: Devices, systems and methods are provided for facilitating knee balancing during a knee replacement surgery. A system can include a force sensor, a main body, a moveable sensor platform, and an adjustment mechanism. The force sensor can sense one or more forces applied within a knee joint, including forces applied on a medial side and a lateral side. The movable sensor platform can be coupled between the force sensor and the main body. The adjustment mechanism can adjust the moveable sensor platform, relative to the main body, thereby adjusting a collective height of the system. A method can include inserting portions of a knee balancing system into a gap formed between a cut distal end of a femur and a cut proximal end of a tibia, adjusting an adjustable mechanism of the system to increase or decrease a collective system height, and sensing and displaying the medial and lateral forces.

Abstract: A pressure pulse wave sensor includes: a sensor chip including: a pressure-sensitive element row configured by a plurality of pressure-sensitive elements arranged in one direction; and a chip-side terminal portion placed in an end portion in the one direction of a pressure-sensitive surface on which the pressure-sensitive element row is formed, and electrically connected to the pressure-sensitive element row; and a substrate including a concave portion, the sensor chip fixed to a bottom surface of the concave portion, a substrate-side terminal portion for being electrically connected to the chip-side terminal portion is disposed on a surface of the substrate in which the concave portion is formed, and the pressure pulse wave sensor further includes: an electroconductive member connecting the chip-side terminal portion and the substrate-side terminal portion to each other; and a protective member covering the electroconductive member.

Abstract: Parametric model based computer implemented methods for determining the stiffness of a bone, systems for estimating the stiffness of a bone in vivo, and methods for determining the stiffness of a bone. The computer implemented methods include determining a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f) and fitting a parametric mathematical model to Y(f) and to H(f). The systems include a device for measuring the stiffness of the bone in vivo and a data analyzer to determine a complex compliance frequency response function Y(f) and an associated complex stiffness frequency response function H(f). The methods for determining the stiffness include fitting a parametric model to stiffness of the skin-bone complex as a function of frequency H(f) and the compliance of the skin-bone complex as a function of frequency Y(f).

Abstract: A steerable guidewire. The steerable guidewire is fabricated includes an outer tube, an inner tube, a hub, and a distal articulating region. The steerable guidewire hub can be removed to permit advancement of catheters over its proximal end followed by re-attachment of the hub to permit deflection of the distal end of the steerable guidewire.

Abstract: Embodiments of a syringe-based device for procuring bodily fluid samples can include a housing having a port that can be coupled to a lumen-defining device for receiving bodily fluids, an actuator mechanism retained at least partially within the housing, the actuator mechanism including a pre-sample reservoir, a plunger operably coupled with pre-sample reservoir, a plunger cap, a plunger tube, a valve, a plunger seal, an a selectively attachable collection vial for capturing a bodily fluid sample.

Abstract: A system includes a processor in communication with a set of bioelectrical sensors and a user interface device that provides functionality to monitor one or more bioelectrical signals from a set of bioelectrical electrodes. Processor automatically adjusts a selected one of: (i) a resting threshold; and (ii) a switch threshold that is greater than the resting threshold based at least in part on a trend of the bioelectrical signal. The processor determines whether an amplitude of the bioelectrical signal is less than the resting threshold. In response to determining that the amplitude is less than the resting threshold, the processor determines whether an amplitude of the bioelectrical signal subsequently is equal to or greater than the switch threshold. In response to determining that the bioelectrical signal is greater than the switch threshold, the processor triggers the user interface device with a switch signal.

Abstract: A method and system for operating a neural feedback system is disclosed. The method includes recording brain waves of a user, recording sensor data measuring at least one of a physical state or an activity of the user, and generating recorded context-based brain wave information by detecting correlations between the recorded brain waves and the recorded sensor data. The method further includes identifying recorded context-based brain wave patterns in the recorded context-based brain wave information and associating at least one rule of at least one electronic device with at least one recorded context-based brain wave pattern.

Abstract: A biopsy device includes an elongated probe having a central longitudinal axis, a proximal end, and a distal end. A tissue penetrating tip includes a proximal base and a sharp distal point. The proximal base is secured to the distal end of the elongated probe. The sharp distal point is distal to the proximal base and is aligned with the central longitudinal axis. The tissue penetrating tip has a plurality of concave surfaces annularly arranged to form at least three adjacent pairs of concave surfaces. Each concave surface of the plurality of concave surfaces extends from the proximal base to the sharp distal point. Each adjacent pair of concave surfaces intersect to form a concave curved cutting edge. Cumulatively, the at least three adjacent pairs of concave surfaces form a plurality of concave curved cutting edges that distally terminate at the sharp distal point.

Abstract: A guidewire manipulation system may include a cylindrical drum, having a cylindrical outer drum surface with a helical groove for housing a flexible guidewire and an anchoring mechanism for attaching the flexible guidewire to the drum. The system may also include an outer shell or belt disposed around the drum, forming an opening through which the flexible guidewire exits. The system may also include a first actuator coupled with the drum for rotating the drum about a first axis, and a second actuator coupled with the drum for rotating the system about a second axis.

Abstract: A system and method detect neuronal action potential signals from tissue responding to electrical stimulation signals. A sparse signal space model for a set of tissue response recordings has a signal space separable into a plurality of disjoint component manifolds including a neural action potential (NAP) component manifold corresponding to tissue response to electrical stimulation signals. A response measurement module is configured to: i. map a tissue response measurement signal into the sparse signal model space to obtain a corresponding sparse signal representation, ii. project the sparse signal representation onto the NAP component manifold to obtain a sparse NAP component representation, iii. when the sparse NAP component representation is greater than a minimum threshold value, report and recover a detected NAP signal in the tissue response measurement signal.

Abstract: Systems and methods of monitoring electrodermal activity (EDA) in human subjects suitable for use in wearable electronic devices. An EDA monitoring system can include first and second dry electrodes, an alternating current (AC) excitation signal source, a trans-impedance amplifier, an analog-to-digital (A-to-D) converter, a discrete Fourier transform (DFT) processor, and a microprocessor. The AC excitation signal source can produce an AC excitation signal having a predetermined excitation frequency, such as about 100 or 120 Hertz (Hz). The analog-to-digital (A-to-D) converter can include a sample-and-hold circuit that operates at a predetermined sampling frequency, such as about four times (4×) the predetermined excitation frequency of 100 or 120 Hz. The DFT processor can generate complex frequency domain representations of digitized, sampled voltage level sequences provided by the A-to-D converter for use in obtaining measures of a user's skin impedance or skin conductance.

Abstract: The present invention relates to systems and methods for characterizing at least one anatomical parameter of an upper airway of a patient by analysing spectral properties of an utterance, comprising: a mechanical coupler comprising means for restricting the jaw position of the patient; means for recording an utterance; and processing means for determining at least one anatomical parameter of the upper airway from the recorded utterance and comparing the recorded utterance to a threshold value. In addition the present invention relates to the use of the above mentioned systems as a diagnostics tool for assessing obstructive sleep apnea.

Abstract: A system is provided for monitoring a patient on an air support system. The system comprises a capacitive sensor system having a capacitive sensor positioned at the underside of an air filled mattress, and a respiration signal processing module that receives the output of the capacitive sensor system and is configured to monitor patient respiration. Respiration is monitored by: periodically sampling the capacitive sensor system output to obtain measurements of incremental body displacement; analyzing a plurality of the samples to determine one or more values for parameters of patient respiratory rate; and determining when one or more of the parameter values indicate abnormal respiration. A corresponding method and computer program are also provided.

Abstract: A method and system to obtain and process data indicative of muscle reflexes for screening and/or diagnosing a patient with a brain injury or spinal cord injury, and especially for obtaining and processing data indicative of reflexes from the bulbospongiosus muscle. Certain embodiments employ a novel electromechanical probe for stimulating the bulbospongiosus muscle to identify a time of the stimulation so that electrical responses from electrodes on the patient's skin can be identified for analysis.

Abstract: In one example, a method of estimating lung fluid content includes receiving a first response signal in response to a delivered first test stimulus, the first test stimulus delivered and the first response signal obtained during a first subject state, receiving a first estimate of a fluid content value during the first subject state, receiving a second response signal in response to a delivered second test stimulus, the second test stimulus delivered and the second response signal obtained during a second subject state, receiving a second estimate of the fluid content value during the second subject state, pairing the first response signal and the first estimate of the fluid content value to form a first pair of values and pairing the second response signal and the second estimate of the fluid content value to form a second pair of values, and determining a relationship between the pairs of values.

Abstract: A medical device including an electric measurement circuit, in which are connected at least two sensors the impedance of which varies as a function of a sensed physical parameter, a source of electrical power for powering the electric measurement circuit, an antenna for emitting an electromagnetic field as a function of the impedance of the electric measurement circuit, each of the sensors being associated with a switch for short circuiting the sensor in the measurement circuit, the medical device further including a system for controlling the switches in order successively to command the opening or closing of the switches in determined configurations. The medical device may notably be able to be applied to the human body or implanted in the human body.