Patents Examined by Yvonne Eyler
  • Enantiomerically enriched 2-butanol
    Patent number: 7396964
    Abstract: The present invention relates to a process for preparing enantiomerically enriched 2-butanol and to its use.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: July 8, 2008
    Assignee: LANXESS Deutschland GmbH
    Inventors: Björn Schlummer, Martin Stürmann
  • Perturbed membrane-binding compounds
    Patent number: 7396859
    Abstract: The present invention provides uses of compounds that bind selectively to cells undergoing perturbations and alterations of their normal membrane organization, while binding to a lesser degree to cell having membranes of normal organization. These compounds are termed perturbed-membrane-binding compounds (PMBC). The PMBC group of compounds includes new compounds and also known compounds.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: July 8, 2008
    Assignee: NST Neurosurvival Technologies, Ltd.
    Inventors: Ilan Ziv, Anat Shievan, Sharon Ebner
  • Process for stably operating a continuous preparation process for obtaining acrolein or acrylic acid or a mixture thereof from propane
    Patent number: 7396956
    Abstract: A process for stably operating a continuous preparation process for obtaining acrolein or acrylic acid or a mixture thereof from propane, in which the feed rate of fresh propane to the process is utilized as a correcting element for stable steady-state operation.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: July 8, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Martin Dieterle, Götz-Peter Schindler, Catharina Klanner
  • Fluorinated compound, water repellent composition and thin film
    Patent number: 7393515
    Abstract: To provide a fluorinated compound, which can readily form a thin film having a hydrophobic/hydrophilic pattern, by employing an ultraviolet light having a relatively low energy.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: July 1, 2008
    Assignee: Asahi Glass Company, Limited
    Inventors: Taiki Hoshino, Yutaka Furukawa, Takashi Okazoe
  • Intermediates in producing phenoxyacetic acid derivatives and method of using the same
    Patent number: 7393968
    Abstract: The present invention provides novel intermediates represented by general formula (I) etc. for preparing a phenoxyacetic acid derivative represented by general formula (X) or a pharmaceutically acceptable salt thereof, which has ?3-adrenoceptor stimulating activity and are useful for treating or preventing obesity, hyperglycemia, diseases caused by intestinal hypermotility, pollakiuria, urinary incontinence, depression or biliary calculus.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: July 1, 2008
    Assignee: Kissei Pharmaceutical Co., Ltd.
    Inventors: Nobuyuki Tanaka, Tetsuro Tamai, Harunobu Mukaiyama, Takehiro Ishikawa, Junichi Kobayashi, Satoshi Akahane, Hiromu Harada
  • Process for the preparation of cinacalcet base
    Patent number: 7393967
    Abstract: Provided is a process for preparing cinacalcet, (R)-?-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: July 1, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventor: Revital Lifshitz-Liron
  • Dicopper(I) oxalate complexes as precursor for metallic copper deposition
    Patent number: 7393555
    Abstract: The invention relates to dicopper(I) oxalate complexes stabilized by neutral Lewis bases, such as alkenes or alkynes, and to the use of dicopper(I) oxalate complexes as precursors for the deposition of metallic copper, in which the neutral Lewis bases used are alkynes, alkenes, triarylphosphines, CO or isonitriles.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: July 1, 2008
    Assignee: BASF Aktiengesellschaft
    Inventor: Katrin Koehler
  • Preparation of ketals
    Patent number: 7390930
    Abstract: The invention relates to a process for ketalizing triacetonamine by reacting triacetonamine and a hydroxyl derivative, for example, a mono- or polyhydric alcohol, with gaseous hydrogen chloride to give an open-chain or cyclic ketal.
    Type: Grant
    Filed: July 16, 2003
    Date of Patent: June 24, 2008
    Assignee: Degussa AG
    Inventors: Oliver Meyer, Renate Uhlenberg, Michael Korell
  • Optimized liquid-phase oxidation
    Patent number: 7390921
    Abstract: Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: June 24, 2008
    Assignee: Eastman Chemical Company
    Inventors: Alan George Wonders, Marcel de Vreede, Lee Reynolds Partin, Wayne Scott Strasser, Puneet Gupta
  • Terphenyl derivatives, preparation thereof, compositions containing same
    Patent number: 7390924
    Abstract: The invention relates to terphenyl derivatives of formula: and to their preparation and to the pharmaceutical compositions comprising them. These compounds exhibit an antagonist activity with respect to CB1 cannabinoid receptors.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: June 24, 2008
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Serge Martinez, Murielle Rinaldi-Carmona
  • Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3
    Patent number: 7390926
    Abstract: The invention provides the diastereoselective alkylation of optically active nopinone to form the compound of formula (I) according to scheme A below: in which: —R is a C5-15 alkyl group; —R1 is especially a C1-15 alkyl, C2-15 alkenyl or C2-15 alkynyl group or a C5-15 aryl, each group optionally being substituted; and —X is a halogen atom; and the configuration of the compound of formula (I) is either (E) or (Z) or a mixture of the two. The compound of formula (I) is a valuable synthetic intermediate.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: June 24, 2008
    Assignee: ZaCh System
    Inventors: Jean-Claude Caille, Marc Mauduit
  • Phenolic acid salts of gabapentin in liquid and/or semi-solid dosage forms and methods of use
    Patent number: 7390922
    Abstract: The present invention relates to pharmaceutical compositions of gabapentin tannate, processes for production of those compositions and methods of use of those compositions. The present invention provides a novel process for preparation of the tannate salt of gabapentin in liquid or semi-solid dosage form for human and veterinary pharmaceutical use. Tannate salts of active pharmaceutical ingredients are used in sustained release applications and to improve certain organoleptic properties such as taste. The process may utilize either natural or synthetic tannic acid.
    Type: Grant
    Filed: March 22, 2004
    Date of Patent: June 24, 2008
    Assignee: Kiel Laboratories, Inc.
    Inventors: Jeffrey S. Kiel, H. Greg Thomas, Narasimhan Mani
  • Cyclopentane carboxylate compounds, process and intermediates for preparing the same and use thereof
    Patent number: 7388103
    Abstract: The present invention discloses cyclopentane carboxylate compounds. The 1-hydrocarbyl-2-acyloxy-cyclopentane carboxylates according to the invention have a general formula (I): wherein groups R1, R2 and R3, which are identical or different, are independently selected from the group consisting of linear or branched C1-C20alkyl, C3-C20cycloalkyl, C6-C20aryl, C7-C20alkaryl and C7-C20aralkyl. The present invention also discloses a process as well as intermediate compounds for preparing the compounds of formula (I), and use of the compounds (I) as electron donor in the preparation of catalysts for propylene polymerization.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: June 17, 2008
    Assignees: China Petroleum & Chemical Corporation, Beijing Research Institute of Chemical Industry
    Inventors: Lunjia Xie, Hongbin Du, Zhibiao Hu, Tianyi Zhang, Siyuan Zhao, Xinsheng Wang
  • Compounds and use to reduce the formation of malodour
    Patent number: 7388105
    Abstract: Malodour formation reducing compounds alpha-N-(3-Methyl-5-phenylpentanoxycarbonyl)-L-glutamine, alpha-N-(2-Methyl-5-phenylpentanoxycarbonyl)-L-glutamine, and alpha-N-(2,4-Dimethyl-4-phenylbutanoxycarbonyl)-L-glutamine, and their salts, compositions comprising such compounds, including cosmetic products, personal care products, and deodorant products, and methods forming such products and their use. The compounds are useful to reduce the formation of human malodour resulting from bacterial degradation of compounds naturally present in sweat, in particular axilliary malodour.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: June 17, 2008
    Assignee: Givaudan S.A.
    Inventors: Andreas Natsch, Felix Flachsmann
  • Method of preparing organomagnesium compounds
    Patent number: 7387751
    Abstract: The present invention is directed to a reagent for use in the preparation of organomagnesium compounds as well as to a method of preparing such organomagnesium compounds. The present invention furthermore provides a method of preparing functionalized or unfunctionalized organic compounds as well as the use of the reagents of the present invention in the preparation of organometallic compounds and their reaction with electrophiles. Finally, the present invention is directed to the use of lithium salts—LiY in the preparation of organometallic compounds and their reactions with electrophiles and to an organometallic compound which is obtainable by the disclosed method.
    Type: Grant
    Filed: April 18, 2007
    Date of Patent: June 17, 2008
    Assignee: Ludwig-Maximilians-Universitat Munchen
    Inventors: Paul Knochel, Arkady Krasovskiy
  • Manufacture of polytrimethylene ether glycol
    Patent number: 7388115
    Abstract: The present invention relates to a process of manufacture of polytrimethylene ether glycol, in which one or more inorganic compounds selected from alkali metal carbonates are utilized during certain purification steps to reduce phase separation time.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: June 17, 2008
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Hari Babu Sunkara, Howard C. Ng
  • Non-nucleoside reverse transcriptase inhibitors
    Patent number: 7388111
    Abstract: The present invention provides for compounds useful for treating an HIV-1 infection, or preventing an HIV-1 infection, or treating AIDS or ARC. The compounds of the invention are of formula I wherein R1-R4 and Ar are as herein defined.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: June 17, 2008
    Assignee: Roche Palo Alto LLC
    Inventors: Taraneh Mirzadegan, Tania Silva
  • Process for preparing acrolein or acrylic acid or a mixture thereof from propane
    Patent number: 7388106
    Abstract: A process for preparing acrolein or acrylic acid or a mixture thereof from propane, in which propane is dehydrogenated under heterogeneous catalysis in a reaction zone A and the propylene formed is partially oxidized heterogeneously in a reaction zone, reaction zone A being operated in loop mode and reaction gas mixture input stream A fed to the reaction zone A comprising added molecular hydrogen which is added to this input stream as late as possible.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: June 17, 2008
    Assignee: BASF Aktiengesellschaft
    Inventors: Catharina Klanner, Martin Dieterle, Goetz-Peter Schindler, Tsung-Chieh Cheng, Klaus Joachim Mueller-Engel
  • Stearate composition and method
    Patent number: 7385068
    Abstract: An improved alkaline earth metal stearate composition is disclosed and is prepared by reacting a fatty acid component including stearic acid and palmitic acid with an alkali hydroxide to form an alkaline soap. An aqueous metal salt solution is then added to the soap, and pH adjusted to less than about pH 8 to form the improved alkaline earth metal stearate. The improved alkaline earth metal stearate provides a substantially pure amount of the dihydrate form of the stearate.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: June 10, 2008
    Assignee: Mallinckrodt Inc.
    Inventors: Todd P. Heider, Steven M. Wolfgang, Scot R. Randle
  • Process for producing fluorine-containing diol and its derivatives
    Patent number: 7385091
    Abstract: A process for producing a fluorine-containing diol represented by the formula [2], includes reducing a hydroxy ketone represented by the formula [1], by hydrogen in the presence of a ruthenium catalyst. The ruthenium catalyst may be a solid-phase catalyst in which ruthenium is carried on an activated carbon, alumina or silica.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: June 10, 2008
    Assignee: Central Glass Co., Ltd.
    Inventors: Takeo Komata, Makoto Matsuura, Kei Matsunaga