Abstract: A multiple chamber IV manifold delivery device for controlling infusion of blood, medical drugs or other solutions to a medical patient. The manifold includes a transparent housing defining a set of drip chambers that communicate with a Y-site fluid reservoir that delivers fluid to a conduit line leading to a medical patient. The Y-site reservoir is provided with a flotation check valve. The manifold delivery device is operable to control the order of delivery of at least two fluid solutions from separate supply chambers to a medical patient. The flotation check valve is used to maintain one supply chamber in a sealed condition while another chamber supplies fluid to be administered to a patient. The IV manifold device is provided with exit and entry ports to enable the device to be coupled together with at least two other similarly constructed apparatus to thereby increase the time period for administering drugs of fluids to a medical patient.