Abstract: A system includes a tubing set and a drive assembly. The tubing set includes inlet tubing couplable to a source of fluid, a valve coupled to the inlet tubing, a syringe coupled to the inlet tubing via the valve, and outlet tubing coupled to the valve. The valve is configured to allow fluid to be drawn from the source of fluid via the inlet tubing into a syringe body of the syringe and to be expelled from the syringe body and through the outlet tubing, and to prevent fluid from being drawn from the outlet tubing into the syringe body and to prevent fluid expelled from the syringe body from flowing through the inlet tubing. The drive assembly is configured to reversibly receive the tubing set such that a drive mechanism is engaged with a plunger of the syringe to reciprocally translate the plunger relative to the syringe body.

Abstract: A computer-assisted medical system includes a manipulator, an instrument holder physically coupled to the manipulator arm, and a controller that includes a computer processor. The instrument holder includes an instrument holder carriage configured to releasably couple to an instrument and translate the instrument along a longitudinal axis. The controller applies a signal that represents a movement for the instrument along the longitudinal axis to a filter to differentiate between a first and a second motion component of the movement along the longitudinal axis, and causes the instrument to move in accordance with the movement along the longitudinal axis by commanding the manipulator arm to move based on the first motion component of the movement along the longitudinal axis. The controller further commands, based on the second motion component of the movement along the longitudinal axis, the instrument holder carriage to move relative to the manipulator arm.

Abstract: Systems and methods for constructing an itinerary for a user based on articles of multimedia content are disclosed. One computer-implemented method may include: receiving, at the server and from a user device hosting a media streaming platform, an indication of selection by a user of a travel option associated with an aspect featured in an article of multimedia content presented on the media streaming platform; identifying, based on the receiving, a real-world location of the aspect; ascertaining, by the server, contextual information associated with the user; establishing, based on the real-world location of the aspect and the contextual information associated with the user, the itinerary for travel to the aspect; and presenting, subsequent to the establishing, a visual display of the itinerary on the media-streaming platform. Other aspects are described and claimed.

Abstract: The invention relates to prokaryotic cells for the production of polymers containing non-canonical amino acids, and to methods for making said cells. The invention also relates to newly obtainable polymers as produced by the cells of the invention. In addition, the invention relates to new orthogonal aminoacyl-tRNA synthetases (aaRSs) and orthogonal tRNAs, which may be used in pairs and find utility in host cells such as, but not limited to, the prokaryotic cells of the invention.

Abstract: Boundary information associated with a three-dimensional (3D) flying space is obtained, including a boundary of the 3D flying space. Location information associated with an aircraft is obtained, including a location of the aircraft. Information is presented based at least in part on the boundary information associated with the 3D flying space and the location information associated with the aircraft, including by presenting, in a display, the boundary of the 3D flying space and an avatar representing the aircraft at the location of the aircraft.

Abstract: The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

Abstract: A grooming tool for use on an animal includes a base arrangement sized for grasping by a human hand. A first section of grooming members is secured to the base arrangement and includes flexible members. A second section of grooming members is spaced from the first section and includes flexible members. A third section of rigid grooming members are positioned between the first section and second section of grooming members. The tool can include a grip assembly having a pivotable grip member.

Abstract: The present technology is a prosthetic heart valve device, and related systems and methods, for treating a native valve of a human heart having a native annulus and native leaflets. One embodiment comprises a valve support, a prosthetic valve assembly within the valve support, and an anchoring member having an upstream portion and a downstream portion. The device further includes an extension member coupled to the fixation frame and extending radially outward therefrom. The extension member includes a plurality of discrete fabric segments having a first end at the anchoring member and a second end spaced apart from the anchoring member, wherein each discrete fabric segment includes lateral edges extending from the first end to the second end of the discrete fabric segment. The discrete fabric segments are configured to move circumferentially relative to each other.

Abstract: Systems and methods for apprising a user of a proximately located aspect-of-interest are disclosed. One method may include: receiving an indication of a geographic location associated with the user; identifying an aspect associated with a multimedia content interest of the user; determining whether the geographic location associated is within a predetermined distance to a known location the aspect associated with the multimedia content interest; transmitting, responsive to determining that the geographic location is within the predetermined distance to the known location, instructions to a user device associated with the user to provide a notification to the user; receiving, at the server, another indication that the user has provided interaction input to the notification; and transmitting additional instructions to another device to perform an action that is based on the interaction input.

Abstract: Systems and methods for distributing rewards based on user actions performed in association with multimedia content are disclosed. One computer-implemented method may include: receiving, at the server, an indication of a real-world action performed by a user; identifying, by the server, that the real-world action corresponds to a rewards-based action performed in association with an article of multimedia content present on a media-streaming platform, wherein the rewards-based action at least corresponds to visitation to a geographic location associated with an aspect of the article of multimedia content; determining, by the server, whether performance of the rewards-based action necessitates distribution of a reward to the user, ascertaining, subsequent to determining that performance of the rewards-based action does necessitate distribution of the reward to the user, a type of the reward; and distributing, based on the ascertaining, the reward of the ascertained type to the user.

Abstract: Systems, methods, and computer-readable media are described for compact radar systems. In some examples, a compact radar system can include a first set of transmit antennas, a second set of receive antennas, one or more processors, and at least one computer-readable storage medium storing computer-executable instructions which, when executed by the one or more processors, cause the radar system to coordinate digital beam steering of the first set of transmit antennas and the second set of receive antennas, and coordinate digital beam forming with one or more of the second set of receive antennas to detect one or more objects within a distance of the radar system.

Abstract: Provided are aminopyridine compounds and pharmaceutically acceptable compositions thereof which exhibit inhibition activity against certain mutated forms of EGFR.

Abstract: A tool is provided that includes unitary plate that includes a blade portion and a tang portion. The blade portion can include an edge. The tang portion can include a positioning hole, a first hole, a slot, a second hole, a rivet hole, and one or more teeth (also referred to as one or more barbs) on a side of the tang portion. The tool can further include a hilt member which includes a through passage, a tab, and a notch. The tool includes an overlay on a body to create a handle for gripping the tool. The tool further includes a hammerhead cap on an end of the body, the hammerhead cap is coupled to the handle with a rivet through the rivet hole.

Abstract: Sensor data that includes or more of the following: (1) aircraft state information associated with an aircraft or (2) parachute canopy state information associated with a parachute canopy is received. The parachute canopy is coupled to the aircraft at a point aft of a center of mass of the aircraft. It is determined, based at least in part on the sensor data, whether to generate a control signal associated with maneuvering the aircraft into a nose-up position. A recovery action is performed, including by deploying the parachute canopy; wherein a load on the parachute canopy is reduced in the event the aircraft is in the nose-up position compared to the aircraft being in a nose-down position.

Abstract: A computer-implemented method of object enhancement in endoscopy images includes capturing an image of an object within a surgical operative site via an imaging device, determining a size of the object based on the captured image of the object, displaying the captured image of the object, and displaying on the displayed captured image of the object a representation of the determined size of the object.

Abstract: A plurality of propellers generate vertical thrust at least some of the time. An attachment sub-system detachably couples to a vertical connector, where a plurality of vertically-stacked multicopters are configured to detachably couple to the vertical connector in order to transport a load at a bottom end of the vertical connector. There is an opening in a vehicle frame that is configured to: (1) receive the vertical connector prior to the attachment sub-system detachably coupling to the vertical connector and (2) hold the vertical connector while the attachment sub-system is detachably coupled to the vertical connector.

Abstract: An assembly includes a liftgate having a frame and a body panel supported by the frame, the body panel defining a plurality of openings, the openings providing access to the frame. The assembly includes a first cover covering the plurality of openings of the body panel. The assembly includes a second cover supported by the first cover and defining a chamber therebetween. The assembly includes a sensor assembly supported within the chamber between the first cover and the second cover.