Abstract: Systems and methods for folder synchronization and offline synchronization via a mobile platform in a web-based collaboration environment are disclosed. One embodiment includes synchronizing user selected folders and/or sub-folders via the mobile platform, using portable devices including smart phones and tablets using any mobile operating system to allow offline access. Child or sub-folders of the selected folders and/or sub-folders are automatically detected and synchronized for offline access. Any change or new content detected on the client side or on the server side is also synchronized such that the selected folders and/or sub-folders on the client and server sides are up to date.

Abstract: Small molecule inhibitors of salt inducible kinases (SIKs) are provided. In particular, compounds of formula (II) and compounds of formula (III), and tautomers, stereoisomers, pharmaceutically acceptable salts and solvates thereof are provided. Also provided are pharmaceutical compositions containing the compounds, methods of preparing the compounds, and methods of using the compounds for inhibiting SIKs, such as SIK1 and SIK2, and methods of treating diseases mediated by SIKs.

Abstract: Antenna arrays and structures for propagating electromagnetic signals. A waveguide cross-section is disclosed that may be implemented as a hollow irregular hexagonal metal structure that receives an electromagnetic signal and propagates the electromagnetic signal through the hollow hexagonal metal structure. The waveguide may be fabricated using metal additive manufacturing techniques and include one or more downward facing and unsupported surfaces.

Abstract: A group of glass compositions in the Li2O—Al2O3—SiO2—B2O3 family that can be chemically strengthened in single or multiple ion exchange baths containing at least one of NaNO3 and KNO3 for a short time (2-4 hours) to develop a deep depth of layer (DOL). In some instances, the DOL is at least 70 ?m; in others, at least about 100 ?m. The ion exchanged glasses have a high damage resistance (indentation fracture toughness ranging form greater than 10 kgf to greater than 50 kgf) that is better than or at least comparable to that of sodium aluminosilicate glasses.

Abstract: Computer-implemented system and method that allows for the rehabilitation of individuals with strabismus by leveraging commercially available VR headset technology. Eye tracking capabilities and external cameras of existing VR headsets, enables the system and method to first gather the image that the dominant, unaffected eye is focused on (FIG. 1). Then, given where the strabismus unaffected eye's gaze falls on its screen, the system and method will take the image and identify where that point lies on the strabismus affected eye's screen. This point is the ideal gaze point of the strabismus affected eye. The software solution disclosed herein will then warp the strabismus affected eye's screen so that this new gaze will line up with the unaffected eye's gaze.

Abstract: A system for categorizing, visualizing, and recommending cannabis products based on objective data of the chemical composition of products is described. This system allows cannabis products to be visualized and compared based on their chemical composition, even by laypeople with little or no knowledge of the underlying objective data. A recommendation system is built upon this which can recommend products for consumption, including a user interface for receiving user input, which includes at least one of demographic data, desired level of psychoactivity, or prior experience with the product, a merchant interface for receiving merchant input, including at least one of general data descriptive of the regulated product, lab data descriptive of the regulated products chemical composition, and user data descriptive of subjective effects of the regulated product on a user; and a decision engine making a recommendation of product according to correlation of the lab data with the user data.

Abstract: A method for generating and maintaining hierarchical tags with community-based ratings is provided. Tags for media streams are organized into a hierarchical format. Users may select tags from the hierarchical tag database that describes a particular multimedia content. If the user is unable to locate a desired tag, the user may submit a new tag. Upon submission of the new tag, a librarian approves the tag before storing and placing the tag in the hierarchical tag database. Users are also able to rate the quality of the association between the tag and the multimedia content. If a tag is rated low, the tag may be removed from the hierarchical tag database. If the tag is rated highly, display of the tag in a list of tags becomes more prominent.

Abstract: A driveline includes a driver configured to be positioned between an engine and a transmission. The driver includes a housing, a motor/generator, and a clutch. The housing includes an engine mount configured to couple to the engine and a backing plate configured to couple to the transmission. The motor/generator is disposed within the housing and configured to couple to an input of the transmission. The clutch is disposed within the housing and coupled to the motor/generator. The clutch is configured to selectively couple an output of the engine to the motor/generator. The clutch is configured to be spring-biased into engagement with the engine and pneumatically disengaged by an air supply selectively provided thereto.

Abstract: A method used for planning radiation treatment accessing information that includes calculated doses and calculated dose rates for sub-volumes in a treatment target, and also accessing information that includes values of a measure of the sub-volumes as a function of the calculated doses and the calculated dose rates. A graphical user interface includes a rendering that is based on the calculated doses, the calculated doses rates, and the values of the measure.

Abstract: A graphics processing system includes a tiling unit configured to tile a scene into a plurality of tiles. A processing unit identifies tiles of the plurality of tiles that are each associated with at least a predetermined number of primitives. A memory management unit allocates a portion of memory to each of the identified tiles and does not allocate a portion of memory for each of the plurality of tiles that are not identified by the processing unit. A rendering unit renders each of the identified tiles and does not render tiles that are not identified by the processing unit.

Abstract: A glass composition includes greater than or equal to 45 mol % to less than or equal to 60 mol % SiO2; greater than or equal to 15 mol % to less than or equal to 25 mol % Al2O3; greater than or equal to 10 mol % to less than or equal to 20 mol % Li2O; greater than or equal to 0 mol % to less than or equal to 7.5 mol % Na2O; greater than or equal to 0 mol % to less than or equal to 5 mol % K2O; greater than or equal to 7 mol % to less than or equal to 13 mol % P2O5, and greater than or equal to 0 mol % to less than or equal to 4 mol % TiO2. The glass composition may have a liquidus temperature of less than or equal to 1300° C. and an inter-diffusion coefficient greater than or equal to 4000 ?m2/hour. The glass composition is chemically strengthenable. The glass composition may be used in a glass-based article or a consumer electronic product.

Abstract: Disclosed herein are coronavirus Spike (S) proteins and nanoparticles comprising the same, which are suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.

Abstract: A glass-based article including a first surface and a second surface opposing the first surface defining a thickness (t) of about 3 millimeters or less (e.g., about 1 millimeter or less), and a stress profile, wherein all points of the stress profile between a thickness range from about 0·t up to 0.3·t and from greater than about 0.7·t to t, comprise a tangent with a slope having an absolute value greater than about 0.1 MPa/micrometer. In some embodiments, the glass-based article includes a non-zero metal oxide concentration that varies along at least a portion of the thickness (e.g., 0·t to about 0.3·t) and a maximum central tension of less than about 71.5/?(t) (MPa). In some embodiments, the concentration of metal oxide or alkali metal oxide decreases from the first surface to a point between the first surface and the second surface and increases from the point to the second surface. The concentration of the metal oxide may be about 0.05 mol % or greater or about 0.

Abstract: Systems and techniques for adjusting experiment parameters are illustrated. One embodiment includes a method that defines a joint distribution, wherein the joint distribution corresponds to a combination of a probabilistic model and a point prediction model, and wherein the point prediction model is configured to obtain a measurement of regression accuracy. The method derives an energy function for the joint distribution. The method obtains, from the energy function for the joint distribution, an approximation for a conditional distribution, wherein an output of the point prediction model is a parameter of the approximation. The method determines, from a loss function, at least one training parameter. The method trains the probabilistic based on the at least one parameter to operate as a conditional generative model, wherein the trained probabilistic model follows the conditional distribution. The method applies the trained probabilistic model to a dataset corresponding to a randomized trial.

Abstract: The present disclosure is generally directed towards a clean drain system. The clean drain system includes drain stopper system, a seal, and a flange. The seal is coupled to the flange. The drain stopper system is positioned through the seal. The drain stopper system further includes a drain cover, a drain housing, and a basket. The drain cover along a vertical axis to allow or prevent the flow of water through the tailpipe. The basket includes a plurality of openings. The basket is configured to catch debris as it flows downward through the drain to prevent the drain from clogging. The clean drain system further includes an overflow cover, an overflow tube, and a collar. The collar is positioned around the drain housing. The overflow cover is coupled to the overflow tube. The collar is coupled to another end of the overflow tube.

Abstract: Systems and techniques for adjusting experiment parameters are illustrated. One embodiment includes a method that defines a joint distribution, wherein the joint distribution corresponds to a combination of a probabilistic model and a point prediction model, and wherein the point prediction model is configured to obtain a measurement of regression accuracy. The method derives an energy function for the joint distribution. The method obtains, from the energy function for the joint distribution, an approximation for a conditional distribution, wherein an output of the point prediction model is a parameter of the approximation. The method determines, from a loss function, at least one training parameter. The method trains the probabilistic based on the at least one parameter to operate as a conditional generative model, wherein the trained probabilistic model follows the conditional distribution. The method applies the trained probabilistic model to a dataset corresponding to a randomized trial.

Abstract: Improved soles for shoes, in particular for sports shoes, are described. A sole for a shoe, in particular a sports shoe, is provided, said sole having a cushioning element that includes randomly arranged particles of an expanded material and a control element. The control element is free from expanded material and reduces the shearing motions in a first region of the cushioning element compared to shearing motions in a second region of the cushioning element.

Abstract: A military vehicle include a driveline. The driveline includes a first driver including an engine, an energy storage system, an accessory drive coupled to the engine, a transmission coupled to at least one of the front axle or the rear axle, and a second driver coupled to the engine and the transmission. The accessory drive includes a plurality of accessories and a first motor. The first motor is electrically coupled to the energy storage system. The first motor is positioned to facilitate selectively driving the plurality of accessories. The second driver includes a second motor electrically coupled to the energy storage system.

Abstract: A single-use handle is configured to attach to a working shaft that can support a sounder for measuring the medullary canal of a proximal radius, and a planarizer that is configured to planarize a proximal edge of the proximal radius after the proximal radius has been resected. The handle can further include a plurality of sizing cavities that are configured to receive the resected bone so as to determine the size of the resected bone. The handle can further include an ejector that is configured to decouple the planarizer from the working shaft.

Abstract: A medical device, comprising a fastening assembly, wherein the fastening assembly includes an adapter defining an opening therethrough, a fastener releasably coupled to the adapter, wherein the fastener includes at least two jaws pivotable relative to one another, the fastener having a first configuration wherein the jaws are open and a second configuration wherein the jaws are closed, and at least one cable coupled to the fastener and the adapter, the at least one cable being configured to apply tension to the fastener to transition between the first configuration and the second configuration while the fastener is coupled to the adapter, and to control release of the fastener from the adapter.