Abstract: The present invention relates to a novel benzotriazole derivative compound, a tautomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof, which are related to a compound for inhibiting ENPP1, a composition for inhibiting ENPP1, and a method for inhibiting ENPP1.

Abstract: Described are anti-doppel antibody-drug conjugates, compositions comprising them, and related methods of treating doppel-associated diseases and conditions, including cancer.

Abstract: Disclosed is a window film for a display device including a light transmitting substrate including a polyamide including a structural unit represented by Chemical Formula 1 and a structural unit represented by Chemical Formula 2, and a hard coating layer laminated on one surface of the light transmitting substrate: in Chemical Formula 1 and Chemical Formula 2, each of A1, A2, B, and D is the same as defined in the detailed description.

Abstract: A display device includes a display panel having a folding axis extending in a first direction; and a panel supporter disposed on a surface of the display panel. The panel supporter includes a first layer including a first base resin and first fiber yarns extending in the first direction and dispersed in the first base resin, a second layer disposed on the first layer, the second layer including a second base resin and second fiber yarns extending in a second direction intersecting the first direction and dispersed in the second base resin, and a third layer disposed on the second layer, the third layer including a third base resin and third fiber yarns extending in the first direction and dispersed in the third base resin.

Abstract: Described herein are doppel-targeting molecules (e.g., antibodies) useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.

Abstract: Provided are a method and apparatus for providing a driver interface. The method of providing a driver interface may include, based on a state of a vehicle, determining a main interface configured to display information regarding a vehicle operation service, and generating the determined main interface, wherein the generating of the main interface may include determining a before-starting-work interface as the main interface, in response to the state of the vehicle being switched to a moving-to-workplace state, determining a moving-to-workplace interface as the main interface, and in response to the state of the vehicle being switched to a standby-for-dispatch state, determining a standby-for-dispatch interface as the main interface.

Abstract: Provided herein may be a semiconductor device and a method of manufacturing the semiconductor device. The semiconductor device includes a peripheral circuit structure formed on a substrate including a cell region and a contact region, a cell stacked body formed over the peripheral circuit structure to overlap the cell region, a dummy stacked body formed over the peripheral circuit structure to overlap the contact region, a pillar structure configured to penetrate the cell stacked body, an etch stop layer located over the peripheral circuit structure and overlapping with a bottom surface of the pillar structure, a cutting structure penetrating the pillar structure in a vertical direction and contacting the etch stop layer, and a contact plug penetrating the dummy stacked body and extending to the peripheral circuit structure.

Abstract: The present inventors have arrived at the present application by confirming that a novel quinazolinone derivative exhibits therapeutic efficacy for metabolic disorders. The quinazolinone derivative according to the present application has a similar structure to that of idelalisib, but exhibits very different properties and a different mechanism of action from idelalisib. In addition, this derivative molecule was shown to have excellent efficacy against metabolic disorders, in particular lipid metabolic disorders, through different mechanism of action. The derivative molecule also showed excellent efficacy against non-alcoholic steatohepatitis (NASH). No non-alcoholic steatohepatitis treatment drugs have been approved at the time of filing.

Abstract: Disclosed is a simulation learning-based drowsy driving simulation platform system for detecting careless driving in conjunction with deep learning, the simulation learning-based drowsy driving simulation platform system comprising: a drive state warning device configured to determine a driver's careless driving from a captured image, determine a driver's careless driving determination level, and output the determined level; a smart cruise control interworking part configured to transmit the driver's careless driving determination level outputted from the drive state warning device; and a smart cruise control processing part configured to control a vehicle according to the driver's careless driving determination level transmitted by the smart cruise control interworking part, during a smart cruise control operation.

Abstract: The present disclosure provides a patch attachable to the occlusal plane of posterior teeth, which includes: a drug layer; a backing layer in contact with the drug layer; and a removable part in contact with the backing layer. The patch can be provided as a single-sided type or a double-sided type. It may also be provided as a linear type or a symmetric type. The present disclosure is directed to providing a patch that can be easily attached to the occlusal plane of posterior teeth.

Abstract: An electronic system includes a host device and a storage device including a first memory device of a volatile type and a second memory device of a nonvolatile type. The first memory device is accessed by the host device through a memory-mapped input-output interface and the second memory device is accessed by the host device through a block accessible interface. The storage device provides a virtual memory region to the host device such that a host-dedicated memory region having a first size included in the first memory device is mapped to the virtual memory region having a second size larger than the first size.

Abstract: A storage device includes a storage region in which first data is stored and that is accessed using a first virtual address, and a memory controller configured to control stored data stored in the storage region. The memory controller predicts second data to be accessed using a second virtual address based on the first virtual address, prefetches the second data into an external device, and modifies a physical address mapped to the second virtual address so that the prefetched second data is accessible by a host in communication with the storage device.

Abstract: Provided is a system for verifying a vehicle-based communication service through simulation based on various environments. The system includes a first terminal configured to receive log data and output data from a vehicle terminal equipped in each of a plurality of vehicles, transmit the log data and a reproduction command signal corresponding to the log data, and display the output data and a second terminal configured to receive the log data from the first terminal to upload the log data, perform synchronization of a corresponding system time, and adjust a reproduction time of each of pieces of log data to a predetermined reference point according to the reproduction command signal.

Abstract: A storage device includes a storage region in which first data is stored and that is accessed using a first virtual address, and a memory controller configured to control stored data stored in the storage region. The memory controller predicts second data to be accessed using a second virtual address based on the first virtual address, prefetches the second data into an external device, and modifies a physical address mapped to the second virtual address so that the prefetched second data is accessible by a host in communication with the storage device.

Abstract: An apparatus for switching a control authority of an autonomous vehicle may include: a capturing unit configured to capture an image of the inside of a vehicle and provide the captured image; a storage unit configured to store learning information and weights for inferring the presence and age of a passenger and whether a driver holds a steering wheel, based on deep learning; and a control unit configured to determine whether the passenger can drive the vehicle, by inferring the presence and age of the passenger through the learning information and weights stored in the storage unit from the image inputted from the capturing unit according to a manual mode switch request, infer whether the driver holds the steering wheel, and switch the control authority of the vehicle to a manual mode.

Abstract: An electronic system includes a host device and a storage device including a first memory device of a volatile type and a second memory device of a nonvolatile type. The first memory device is accessed by the host device through a memory-mapped input-output interface and the second memory device is accessed by the host device through a block accessible interface. The storage device provides a virtual memory region to the host device such that a host-dedicated memory region having a first size included in the first memory device is mapped to the virtual memory region having a second size larger than the first size.

Abstract: The present disclosure relates to a novel use of EI24, and provides a novel use of EI24 involved in the improvement of EGFR-TKI drug resistance by inhibiting IGF-1R signaling. According to the present disclosure, the presence or absence of resistance to anti-cancer drugs may be determined by detecting an expression level of EI24. In addition, resistance to anti-cancer drugs may be inhibited, delayed, or improved using EI24 or an activating agent thereof. Moreover, by regulating a pathway of EI24-mediated resistance to anti-cancer drugs, the efficacy of existing anti-cancer drugs may be enhanced, and resistance to anti-cancer drugs may be inhibited, delayed, or improved.

Abstract: A bank interleaving controller may include a power calculator and a write driver. The power calculator may calculate a total power consumption by adding a power consumption of one or more memory banks that are performing write operations and an amount of power that is expected to be additionally consumed to write input data. The write driver may write the input data to a memory cell corresponding to an input address when the total power consumption is equal to or less than a reference power consumption.

Abstract: Provided herein are a pharmaceutical composition for the prevention and treatment of cancer, including, as an active ingredient, E124 protein or a fragment thereof, or an expression vector including a nucleotide sequence encoding the E124 protein or the fragment thereof, and a method of screening a cancer therapeutic agent candidate.

Abstract: A bank interleaving controller may include a power calculator and a write driver. The power calculator may calculate a total power consumption by adding a power consumption of one or more memory banks that are performing write operations and an amount of power that is expected to be additionally consumed to write input data. The write driver may write the input data to a memory cell corresponding to an input address when the total power consumption is equal to or less than a reference power consumption.