Patents by Inventor Aakanksha Khandelwal

Aakanksha Khandelwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retinamide and uses thereof
    Patent number: 9156792
    Abstract: Retinoic acid metabolism blocking agents (RAMBAs). The RAMBAs may be used for treatment of cancer, including breast and prostate cancers. Methods for preparing novel retinamide RAMBAs. The methods include reacting RAMBAs with terminal polar carboxylic acid group with a variety of amines in the presence of suitable coupling reagents. The retinamide RAMBAs are potent inhibitors of the growth of prostate and breast cancer cells and may be useful for the treatment of these diseases in humans.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: October 13, 2015
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Vincent C. O. Njar, Lalji K. Gediya, Aakanksha Khandelwal
  • NOVEL RETINAMIDE RETINOIC ACID METABOLISM BLOCKING AGENTS
    Publication number: 20110059974
    Abstract: Retinoic acid metabolism blocking agents (RAMBAs). The RAMBAs may be used for treatment of cancer, including breast and prostate cancers. Methods for preparing novel retinamide RAMBAs. The methods include reacting RAMBAs with terminal polar carboxylic acid group with a variety of amines in the presence of suitable coupling reagents. The retinamide RAMBAs are potent inhibitors of the growth of prostate and breast cancer cells and may be useful for the treatment of these diseases in humans.
    Type: Application
    Filed: May 7, 2009
    Publication date: March 10, 2011
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Vincent C. O. Njar, Lalji K. Gediya, Aakanksha Khandelwal
  • MUTUAL PRODRUGS AND METHODS TO TREAT CANCER
    Publication number: 20100184812
    Abstract: Mutual prodrugs comprising retinoids and histone deacetylase inhibitors, methods for production of the mutual prodrugs, and methods of treatment comprising administration of the mutual prodrugs. The retinoids include all-trans retinoic acid, 13-cis retinoic acid, and retinoic acid analogs that have a substitution at C-4. Further, the mutual prodrugs of the present invention can be used as therapeutic agents for the treatment of cancer and dermatological diseases and conditions. Pharmaceutical compositions comprising the mutual prodrugs.
    Type: Application
    Filed: June 6, 2008
    Publication date: July 22, 2010
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Vincent C. O. Njar, Lalji K. Gediya, Aakanksha Khandelwal