Patents by Inventor Aaron E. DARLING

Aaron E. DARLING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for introducing mutations
    Patent number: 11421238
    Abstract: The present invention relates to a method for introducing mutations into at least one target nucleic acid molecule comprising (a) providing at least one sample comprising at least one target nucleic acid molecule; and (b) amplifying the at least one target nucleic acid molecule using a low bias DNA polymerase. The present further relates to a use of a low bias DNA polymerase in a method for introducing mutations into one or more nucleic acid molecule(s), a group of sample tags, a method for designing the group of sample tags, a computer readable medium, and a method for preferentially amplifying target nucleic acid molecules.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: August 23, 2022
    Assignee: LONGAS TECHNOLOGIES PTY LTD
    Inventors: Leigh G. Monahan, Joyce To, Catherine M. Burke, Michael Imelfort, Aaron E. Darling
  • Sequencing Algorithm
    Publication number: 20210174905
    Abstract: The invention relates to a method for determining a sequence of at least one target template nucleic acid molecule using non-mutated sequence reads and mutated sequence reads. The invention also relates to a method for determining a sequence of at least one target template nucleic acid molecule in a sample involving controlling or normalising the number of target template nucleic acid molecules in the sample. The invention also relates to a computer programme adapted to perform the method, a computer readable medium comprising the computer programme, and computer implemented methods.
    Type: Application
    Filed: August 12, 2019
    Publication date: June 10, 2021
    Inventors: Michael IMELFORT, Leigh G. MONAHAN, Joyce TO, Catherine M. BURKE, Aaron E. DARLING
  • Method for Introducing Mutations
    Publication number: 20210010008
    Abstract: The present invention relates to a method for introducing mutations into at least one target nucleic acid molecule comprising (a) providing at least one sample comprising at least one target nucleic acid molecule; and (b) amplifying the at least one target nucleic acid molecule using a low bias DNA polymerase. The present further relates to a use of a low bias DNA polymerase in a method for introducing mutations into one or more nucleic acid molecule(s), a group of sample tags, a method for designing the group of sample tags, a computer readable medium, and a method for preferentially amplifying target nucleic acid molecules.
    Type: Application
    Filed: February 19, 2019
    Publication date: January 14, 2021
    Inventors: Leigh G. MONAHAN, Joyce TO, Catherine M. BURKE, Michael IMELFORT, Aaron E. DARLING