Patents by Inventor Aaron Goerke

Aaron Goerke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of adenovirus purification
    Publication number: 20080118970
    Abstract: A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
    Type: Application
    Filed: December 7, 2007
    Publication date: May 22, 2008
    Inventors: John Konz, Ann Lee, Chi To, Aaron Goerke
  • Methods of adenovirus purification
    Publication number: 20050196854
    Abstract: A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
    Type: Application
    Filed: May 13, 2003
    Publication date: September 8, 2005
    Inventors: John Konz, Ann Lee, Chi To, Aaron Goerke
  • Methods of adenovirus purification
    Publication number: 20050153420
    Abstract: A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
    Type: Application
    Filed: May 13, 2003
    Publication date: July 14, 2005
    Inventors: John Konz Jr., Ann Lee, Chin To, Aaron Goerke