Abstract: In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T1 greater than 15 seconds and a water-octanol partition coefficient between ?1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, the imaging agent includes a carbon-13 enriched alcohol.

Abstract: In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T.sub.1 greater than 15 seconds and a water-octanol partition coefficient between ?1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, the imaging agent includes a carbon-13 enriched alcohol.

Abstract: In one aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided. The method includes introducing an imaging agent into the subject, the imaging agent including a compound having at least one hyperpolarized nucleus having a T1 greater than 15 seconds and a water-octanol partition coefficient between ?1 and 1, providing at least one excitation signal to the region of interest, the at least one excitation signal configured to invoke a nuclear magnetic resonance (NMR) effect at least in the introduced imaging agent, and detecting an NMR signal emitted by the region of interest in response to the at least one excitation signal. In another aspect, a method of imaging blood flow in a region of interest of a subject using magnetic resonance imaging (MRI) is provided.

Abstract: In one aspect, a method of obtaining magnetic resonance (MR) and radio-frequency impedance mapping (RFIM) data from a region of an object arranged proximate a plurality of radio-frequency (RF) coils is provided. The method comprises detecting nuclear magnetic resonance (NMR) signals emitted from the region to form, at least in part, first MR data, obtaining at least one impedance measurement from the plurality of RF coils to form, at least in part, first RFIM data, and computing a first RFIM map indicating a spatial distribution in the region of at least one dielectric property, the first RFIM map computed based, at least in part, on the first RFIM data and the first MR data.

Abstract: In one aspect, a method of obtaining magnetic resonance (MR) and radio-frequency impedance mapping (RFIM) data from a region of an object arranged proximate a plurality of radio-frequency (RF) coils is provided. The method comprises detecting nuclear magnetic resonance (NMR) signals emitted from the region to form, at least in part, first MR data, obtaining at least one impedance measurement from the plurality of RF coils to form, at least in part, first RFIM data, and computing a first RFIM map indicating a spatial distribution in the region of at least one dielectric property, the first RFIM map computed based, at least in part, on the first RFIM data and the first MR data.

Abstract: In one aspect, a method of obtaining magnetic resonance (MR) and radio-frequency impedance mapping (RFIM) data from a region of an object arranged proximate a plurality of radio-frequency (RF) coils is provided. The method comprises detecting nuclear magnetic resonance (NMR) signals emitted from the region to form, at least in part, first MR data, obtaining at least one impedance measurement from the plurality of RF coils to form, at least in part, first RFIM data, and computing a first RFIM map indicating a spatial distribution in the region of at least one dielectric property, the first RFIM map computed based, at least in part, on the first RFIM data and the first MR data.