Patents by Inventor Abdelkader Zebda
Abdelkader Zebda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240180958Abstract: A transdermal dihydrogen delivery device including a body including an anode and a cathode, and an electrical energy source, wherein the body is based on a flexible material, capable of shaping to the skin of a human or animal body, and the body includes a water receptacle, the relative arrangement of the receptacle, the anode and the cathode being configured such that the water contained in the receptacle is in contact with the anode and the cathode to form a closed electrical circuit, so as to produce dihydrogen at the cathode from the water taken from the receptacle, to release transdermally the dihydrogen produced. The proposed delivery device is relatively non-invasive, while allowing dihydrogen delivery.Type: ApplicationFiled: April 4, 2022Publication date: June 6, 2024Inventors: Abdelkader ZEBDA, Philippe CINQUIN, Awatef BEN TAHAR, Véronique COIZET
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Publication number: 20240039007Abstract: A composition for manufacturing an electrode, the composition including an electrically conductive carbon-based compound, at least one species able to form a catalyst, and cellulose microfibrils encapsulating chitosan. The cellulose microfibrils create a fibrous mesh binding the composition while limiting coating of the catalyst. Thus, the catalyst remains accessible to the surrounding environment, to allow the redox reactions at the electrode. The electrochemical performances of the electrode are consequently improved. The composition is furthermore particularly adapted for shaping an electrode by 3D printing.Type: ApplicationFiled: February 2, 2022Publication date: February 1, 2024Inventors: Myriam GHODHBANE, Davide BENEVENTI, Didier CHAUSSY, Mohamed Naceur BELGACEM, Lionel DUBOIS, Abdelkader ZEBDA
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Publication number: 20230218211Abstract: A method for determining a region in which the actual concentration is located, in a medium, of a substrate made up of any molecule likely to undergo catalysed oxidation-reduction by a catalyst. The method includes the following steps: taking at least one group of at least two biosensors, each biosensor having a calibration curve of the signal induced by the oxidation-reduction reaction and having identical initial portions of their calibration curves up to a concentration value of the substrate from which the measurement of the signal differ; and when more than one group is present, the biosensors in different groups having different calibration curves without identical initial portions; placing the biosensors in contact with the medium; measuring the signal induced by the oxidation or reduction reaction for each biosensor in the group/groups; comparing all the signal values produced by the biosensors and following the method described in the description.Type: ApplicationFiled: June 11, 2021Publication date: July 13, 2023Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLE, CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE ALPESInventors: Abdelkader ZEBDA, Philippe CINQUIN, Don MARTIN
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Patent number: 11660314Abstract: A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.Type: GrantFiled: December 21, 2018Date of Patent: May 30, 2023Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Philippe Cinquin, Abdelkader Zebda, Jean-Pierre Alcaraz, Donald Keith Martin
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Patent number: 11469433Abstract: Thermo-electric generator which is intended to be immersed in a fluid which contains at least one chemical species, comprising two electrodes each having a first end and a second end, the first ends being connected to each other, the generator being configured to generate an electrical voltage between the two ends when a temperature difference is imposed between each first end and the corresponding second end, the temperature difference being such that one end, referred to as the “hot end”, of each electrode has a temperature which is strictly greater than the temperature of the other end. The hot end of at least one electrode comprises a micro-organism or an enzyme which is capable of causing at least one exothermic reaction involving the chemical species.Type: GrantFiled: May 23, 2019Date of Patent: October 11, 2022Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER RÉGIONAL DE GRENOBLEInventors: Abdelkader Zebda, Philippe Cinquin, Jean-Pierre Alcaraz, Donald Martin, Aziz Bakri, Nawel Khalef
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Publication number: 20220275420Abstract: A biomass-based enzymatic biocathode based on glucose, monosaccharide, ketone or aldehyde includes a collector conductor support, conductive particles disposed on and bound to said collector conductor support, and an aldose reductase disposed on said conductive particles, being bound thereto by adsorption and accessible at the surface of the monosaccharide, ketone or aldehyde reagent that is to be reduced when the biocathode is operational.Type: ApplicationFiled: July 27, 2020Publication date: September 1, 2022Applicants: UNIVERSITÉ GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MEDICALE - INSERM, GRENOBLE INP (INSTITUT NATIONAL POLYTECHNIQUE), CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Abdelkader ZEBDA, Philippe CINQUIN, Donald MARTIN, Thomas SORANZO
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Publication number: 20210196962Abstract: Thermo-electric generator which is intended to be immersed in a fluid which contains at least one chemical species, comprising two electrodes each having a first end and a second end, the first ends being connected to each other, the generator being configured to generate an electrical voltage between the two ends when a temperature difference is imposed between each first end and the corresponding second end, the temperature difference being such that one end, referred to as the “hot end”, of each electrode has a temperature which is strictly greater than the temperature of the other end. The hot end of at least one electrode comprises a micro-organism or an enzyme which is capable of causing at least one exothermic reaction involving the chemical species.Type: ApplicationFiled: May 23, 2019Publication date: July 1, 2021Inventors: Abdelkader ZEBDA, Philippe CINQUIN, Jean-Pierre ALCARAZ, Donald MARTIN, Aziz BAKRI, Nawel KHALEF
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Patent number: 10960191Abstract: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.Type: GrantFiled: April 4, 2016Date of Patent: March 30, 2021Assignees: UNIVERSITE GRENOBLE ALPES, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLEInventors: Philippe Cinquin, Dominique Schneider, Max Maurin, Donald Martin, Sarra El Ichi, Abdelkader Zebda, Jean-Pierre Alcaraz, Fabian Reche, Patrick Tuvignon, Jacques Thelu, Audrey Le Gouellec, Bertrand Toussaint
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Publication number: 20200390802Abstract: A device intended to be implanted in a human or animal body, in order to produce hydrogen in situ from molecules present in the body medium in which the device is implanted, this device having an anode and a cathode, which are each electrically connected to a pole of an electrical energy source, and having a semi-permeable material separating the electrodes from the body medium, in which device, when the connection to the electrical energy source is effective in situ, in the presence of body fluid, a closed electrical circuit is formed, with production of hydrogen at the cathode, the semi-permeable material having a cutoff threshold of between 50 and 500 Da.Type: ApplicationFiled: December 21, 2018Publication date: December 17, 2020Inventors: Philippe CINQUIN, Abdelkader ZEBDA, Jean-Pierre ALCARAZ, Donald MARTIN
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Patent number: 10316284Abstract: The invention concerns a bioreactor obtained by compressing a mixture of an enzyme, a conductor and chitosan. The conductor can consist of carbon nanotubes. This bioreactor can be produced according to the following steps: preparing a mixture of powders in which the proportion of enzyme powder relative to a carbon nanotube powder is of the order of 50/50 by weight; preparing a viscous solution of chitosan in a ratio of 5 to 15 (in mg) of chitosan to 0.75 to 1.25 (in ml) of acetic acid diluted to 0.4 to 0.6% by volume in water; adding the viscous chitosan to the mixture of powders in a proportion be weight of 3 to 5 of powder to 5 to 10 of chitosan; carrying out a first compression followed by light grinding; carrying out a second compression to produce a pellet; and drying at ambient temperature.Type: GrantFiled: March 23, 2015Date of Patent: June 11, 2019Assignee: Universite Grenoble AlpesInventors: Sarra El Ichi, Donald K. Martin, Philippe Cinquin, Abdelkader Zebda
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Publication number: 20180078746Abstract: The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.Type: ApplicationFiled: April 4, 2016Publication date: March 22, 2018Inventors: Philippe CINQUIN, Dominique SCHNEIDER, Max MAURIN, Donald MARTIN, Sarra EL ICHI, Abdelkader ZEBDA, Jean-Pierre ALCARAZ, Fabian RECHE, Patrick TUVIGNON, Jacques THELU, Audrey LE GOUELLEC, Bertrand TOUSSAINT
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Publication number: 20170081626Abstract: The invention concerns a bioreactor obtained by compressing a mixture of an enzyme, a conductor and chitosan. The conductor can consist of carbon nanotubes. This bioreactor can be produced according to the following steps: preparing a mixture of powders in which the proportion of enzyme powder relative to a carbon nanotube powder is of the order of 50/50 by weight; preparing a viscous solution of chitosan in a ratio of 5 to 15 (in mg) of chitosan to 0.75 to 1.25 (in ml) of acetic acid diluted to 0.4 to 0.6% by volume in water; adding the viscous chitosan to the mixture of powders in a proportion be weight of 3 to 5 of powder to 5 to 10 of chitosan; carrying out a first compression followed by light grinding; carrying out a second compression to produce a pellet; and drying at ambient temperature.Type: ApplicationFiled: March 23, 2015Publication date: March 23, 2017Applicant: Universite Grenoble AlpesInventors: Sarra EL ICHI, Donald K. MARTIN, Philippe CINQUIN, Abdelkader ZEBDA
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Publication number: 20130284596Abstract: The invention relates to a biopile electrode or biosensor electrode intended to be immersed in a liquid medium containing a target and an oxidizer, respectively a reducer, in which the anode comprises an enzyme able to catalyse the oxidation of a target, and the cathode comprises an enzyme able to catalyse the reduction of the oxidizer, and in which each of the anode electrode and cathode electrode consists of a solid agglomeration of carbon nanotubes mixed with the enzyme, and is secured to an electrode wireType: ApplicationFiled: August 18, 2011Publication date: October 31, 2013Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIERInventors: Abdelkader Zebda, Alan Le Goff, Michael Holzinger, Serge Cosnier