Abstract: An adsorptive separation device is disclosed having at least one spiral wound adsorption membrane situated around the periphery of a core mandrel wherein the flow is radial from a feed plenum situated between the core mandrel and the membrane, through the membrane to a permeate plenum located between the membrane and a housing for both the core mandrel and the spiral wound membrane. An array of such separation devices is also disclosed showing connections in parallel, in series, in both parallel and in series and in tandem.

Abstract: Adsorptive separation is performed on liquid media by directing the media containing a target substance through an adsorber stage A whereby the target substance is adsorbed; in the last phase of loading stage A and prior to breakthrough of the target substance in the stage A permeate, the stage A permeate is directed to a second adsorber stage B. Upon completion of the stage A loading, the target substance from stage A is eluted with buffer solution, which buffer solution is introduced to stage B, and liquid medium is directed to the preloaded stage A, while stage A is eluted so as both recover the target substance and regenerate the adsorptive capacity of stage A.