Patents by Inventor Abdullah Ibrahim Haj-Yehia

Abdullah Ibrahim Haj-Yehia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disordersB
    Publication number: 20080149097
    Abstract: The present invention relates to multifunctional ?-agonist compounds comprising a reactive oxygen species scavenger group and a nitric oxide donor, and to methods of treating chronic obstructive airway diseases, such as asthma and chronic bronchitis.
    Type: Application
    Filed: March 10, 2008
    Publication date: June 26, 2008
    Applicant: Yissum Research Development Company of Hebrew University of Jerusalem
    Inventor: Abdullah Ibrahim Haj-Yehia
  • Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders
    Patent number: 7378438
    Abstract: The present invention relates to multifunctional ?-agonist compounds comprising a reactive oxygen species scavenger group and a nitric oxide donor, and their use for the treatment of respiratory diseases involving airway obstruction, such as asthma and chronic bronchitis. The invention further relates to methods and devices for administering the compounds.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: May 27, 2008
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventor: Abdullah Ibrahim Haj-Yehia
  • Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
    Patent number: 6759430
    Abstract: The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O2−) scavenger, their preparation and their use in the treatment of conditions associated with oxidative stress or endothelial dysfunction. In particular, the present invention relates to chemical compounds of Formula (I) wherein: R1 may be the same of different and are independently selected from hydrogen, alkoyl, carboxy, hydroxy, amino, amido, cyano, nitro, thio, sulphonyl, sulphoxide alkyl groups comprising an NO-donor, provided that at least one R1 is a group comprising an NO-donor; R2 may be the same or different and are independently selected from alkyl groups; n is an integer 1, 2, or 3; or a salt thereof.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: July 6, 2004
    Assignee: OxoN Medica Inc.
    Inventors: Erik Emil Anggard, Abdullah Ibrahim Haj-Yehia
  • Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
    Publication number: 20030069429
    Abstract: The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O2−) scavenger, their preparation and their use in the treatment of conditions associated with oxidative stress or endothelial dysfunction. In particular, the present invention relates to chemical compounds of formula (I) wherein: R1 may be the same or different and are independently selected from hydrogen, alkoyl, alkoxy, carboxy, hydroxy, amino, amido, cyano, nitro, thio, sulphonyl, sulphoxide alkyl groups comprising an NO-donor, provided that at least one R1 is a group comprising an NO-donor, R2 may be the same or different and are independently selected from alkyl groups; n is an integer 1, 2 or 3; or a salt thereof.
    Type: Application
    Filed: July 25, 2002
    Publication date: April 10, 2003
    Inventors: Erik Emil Anggard, Abdullah Ibrahim Haj-Yehia
  • Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
    Patent number: 6455542
    Abstract: The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O2−) scavenger, their preparation and their use in the treatment of conditions associated with oxidative stress or endothelial dysfunction. For example, the present invention relates to chemical compounds of the formula: wherein R1 may be the same or different and are independently selected from hydrogen, alkoyl, alkoxy, carboxy, hydroxy, amino, amido, cyano, nitro, thio, sulphonyl, sulphoxide alkyl groups and groups comprising an NO-donor, provided that at least one R1 is a group comprising an NO-donor; R2 may the same or different and are independently selected from alkyl groups; n is an integer 1, 2 or 3; or a salt thereof.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: September 24, 2002
    Assignee: Oxon Medica Inc.
    Inventors: Erik Emil Anggard, Abdullah Ibrahim Haj-Yehia
  • Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
    Patent number: 6448267
    Abstract: The present invention relates to chemical compounds comprising a nitric oxide (NO) donor and a superoxide ion (O2−) scavenger, their preparation and their use in the treatment of conditions associated with oxidative stress or endothelial dysfunction. For example, the present invention relates to chemical compounds of the formula: wherein R1 may be the same or different and are independently selected from hydrogen, alkoyl, alkoxy, carboxy, hydroxy, amino, amido, cyano, nitro, thio, sulphonyl, sulphoxide alkyl groups and groups comprising an NO-donor, provided that at least one R1 is a group comprising an NO-donor; R2 may the same or different and are independently selected from alkyl groups; n is an integer 1, 2 or 3; or a salt thereof.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: September 10, 2002
    Assignee: Oxon Medica, Inc.
    Inventors: Erik Emil Anggard, Abdullah Ibrahim Haj-Yehia
  • Piperidine and pyrrolidine derivatives comprising a nitric oxide donor for treating stress
    Publication number: 20020091266
    Abstract: 1
    Type: Application
    Filed: March 6, 2002
    Publication date: July 11, 2002
    Inventors: Erik Emil Anggard, Abdullah Ibrahim Haj-Yehia