Patents by Inventor Abhijit Mazumder

Abhijit Mazumder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogel-based microarray signal amplification methods and devices therefor
    Patent number: 6921638
    Abstract: Methods and devices for detecting nucleic acid and protein targets on hydrogel microarrays are disclosed. Fluorophores are incorporated into the targets and detected. A linear correlation between target concentration and signal amplitude is maintained through the elimination of active enzyme amplification.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: July 26, 2005
    Assignee: Amersham Biosciences AB
    Inventors: Chang-Gong Liu, Abhijit Mazumder, Charles K. Brush, W. Travis Johnson
  • P450 single nucleotide polymorphism biochip analysis
    Publication number: 20040229222
    Abstract: This invention relates to methods and compositions for determining single nucleotide polymorphisms (SNPs) in P450 genes. In preferred embodiments, self extension of interrogation probes is prevented by using novel non self-extension probes and/or methods, thereby improving the specificity and efficiency of P450 SNP detection in target samples with minimal false positive results. The invention thus describes a variety of methods to decrease self-extension of interrogation probes. In addition, this invention provides a unique collection of P450 SNP probes on one assay, primer sequences for specific amplification of each of the seven P450 genes and amplicon control probes to evaluate whether the intended p450 gene targets were amplified successfully. The invention also describes a variety of array platforms for performing the assays of the invention; for example: CodeLink™, eSensor™, multiplex arrays with cartridges etc., all described herein.
    Type: Application
    Filed: April 1, 2002
    Publication date: November 18, 2004
    Inventors: Buena Chui, Robert Elghanian, Vineet Gupta, Krishnamurthy Jayaraman, Gretchen Kiser, Changming Li, Chang-Gong Liu, Kenneth R. Luehrsen, Abhijit Mazumder, Ramesh Ramakrishnan, Arkadiy Silbergleyt, Todd Tuggle, Carl Yamashiro, Handy Yowanto, Ekaterina Pestova, David R. Fermin, David G. Wang, Zhijie John Gu
  • Ratio-based oligonucleotide probe selection
    Publication number: 20030027149
    Abstract: Disclosed herein are methods of selecting probes to target nucleic acid sequences, methods of making oligonucleotide arrays comprising such probes, and methods of using such arrays. Also, described herein are oligonucleotide arrays comprising probes selected by a method of the invention.
    Type: Application
    Filed: August 2, 2001
    Publication date: February 6, 2003
    Inventors: David Dorris, Abhijit Mazumder, Richard D. Shippy
  • Hydrogel-based microarray signal amplification methods and devices therefor
    Publication number: 20020146730
    Abstract: Methods and devices for detecting nucleic acid and protein targets on hydrogel microarrays are disclosed. Fluorophores are incorporated into the targets and detected. A linear correlation between target concentration and signal amplitude is maintained through the elimination of active enzyme amplification.
    Type: Application
    Filed: December 19, 2001
    Publication date: October 10, 2002
    Inventors: Chang-Gong Liu, Abhijit Mazumder, Charles K. Brush, W. Travis Johnson
  • Guanosine-rich oligonucleotide integrase inhibitors
    Patent number: 6355785
    Abstract: A method and compositions for treating viral infection (IV) vitro and in vivo using a guanosine-rich oligonucleotide. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans, and a method for designing guanosine-rich oligonucleotides having anti-viral activity and integrase inhibition activity.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: March 12, 2002
    Assignee: Aronex Pharmaceuticals, Inc.
    Inventors: Robert F. Rando, Susan Fennewald, Joseph G. Zendegui, Joshua O. Ojwang, Michael E. Hogan, Yves Pommier, Abhijit Mazumder