Patents by Inventor Abigail K. R. Lytton-Jean

Abigail K. R. Lytton-Jean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Screening sequence selectivity of oligonucleotide-binding molecules using nanoparticle based colorimetric assay
    Patent number: 7807372
    Abstract: Disclosed herein are methods of screening sequence selectivity of oligonucleotide-binding molecules using a gold nanoparticle based colorimetric assay.
    Type: Grant
    Filed: June 4, 2008
    Date of Patent: October 5, 2010
    Assignee: Northwestern University
    Inventors: Chad A. Mirkin, Sarah J. Hurst, Min Su Han, Abigail K. R. Lytton-Jean
  • SILVER NANOPARTICLE BINDING AGENT CONJUGATES BASED ON MOIETIES WITH TRIPLE CYCLIC DISULFIDE ANCHORING GROUPS
    Publication number: 20100234579
    Abstract: The present invention concerns the use of binding agent-functionalized silver nanoparticles for a variety of uses, including molecular diagnostic labels, synthons in programmable materials synthesis approaches, and functional components for nanoelectronic devices. More specifically, the invention provides a new strategy for preparing silver nanoparticle-binding agent conjugates that are based upon moieties with triple cyclic disulfide-anchoring groups.
    Type: Application
    Filed: May 12, 2008
    Publication date: September 16, 2010
    Applicant: NORTH WESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Jae-Seung Lee, Abigail K.R. Lytton-Jean, Sarah J. Hurst
  • Maximizing Oligonucleotide Loading on Gold Nanoparticle
    Publication number: 20100099858
    Abstract: Increasing the amount of DNA loaded onto gold nanoparticles is disclosed. More particularly, methods of maximizing DNA loading, using salting techniques, sonication, temperature and other such procedures are disclosed.
    Type: Application
    Filed: September 25, 2007
    Publication date: April 22, 2010
    Inventors: Chad A. Mirkin, Abigail K.R. Lytton-Jean, Sarah J. Hurst
  • ASYMMETRIC FUNCTIONALIZATED NANOPARTICLES AND METHODS OF USE
    Publication number: 20090280188
    Abstract: Disclosed herein are asymmetrically functionalized nanoparticles. Further disclosed herein are methods of preparing asymmetrically functionalized nanoparticles. Asymmetrically functionalized nanoparticles can be used in various therapeutic methods.
    Type: Application
    Filed: June 25, 2007
    Publication date: November 12, 2009
    Applicant: Northwestern University
    Inventors: Chad A. Mirkin, Fengwei Huo, Abigail K.R. Lytton-Jean, Xiaoyang Xu, Nathaniel L. Rosi, Yuhuang Wang
  • Colorimetric Screening of DNA Binding/Intercalating Agents with Gold Nanoparticle Probes
    Publication number: 20090221095
    Abstract: Methods are provided to identify and characterize compounds that bind with duplex and triplex polynucleotides.
    Type: Application
    Filed: October 13, 2006
    Publication date: September 3, 2009
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Min Su Han, Abigail K.R. Lytton-Jean
  • SCREENING SEQUENCE SELECTIVITY OF OLIGONUCLEOTIDE-BINDING MOLECULES USING NANOPARTICLE BASED COLORIMETRIC ASSAY
    Publication number: 20080311669
    Abstract: Disclosed herein are methods of screening sequence selectivity of oligonucleotide-binding molecules using a gold nanoparticle based calorimetric assay.
    Type: Application
    Filed: June 4, 2008
    Publication date: December 18, 2008
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: Chad A. Mirkin, Sarah J. Hurst, Min Su Han, Abigail K.R. Lytton-Jean