Patents by Inventor Abraham M. de Vos

Abraham M. de Vos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vascular endothelial cell growth factor variants and uses thereof
    Patent number: 7090834
    Abstract: The present invention provides VEGF variants having one or more amino acid mutations in the KDR and/or FLT-1 receptor binding domains in the native VEGF sequence and selective binding affinity for either the KDR receptor or the FLT-1 receptor. Methods of making the VEGF variants and methods of using the VEGF variants are also provided.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: August 15, 2006
    Assignee: Genentech, Inc.
    Inventors: Brian C. Cunningham, Abraham M. de Vos, Bing Li