Patents by Inventor Abraham Oommen
Abraham Oommen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230366043Abstract: A method of detection of nucleic acids from a biological sample without isolation or purification of the nucleic acids is described. The method may include direct detection of nucleic acids from humans, animals, viruses or bacteria, including DNA and RNA from a biological sample without isolating or purifying nucleic acids prior to analysis. Biological samples may be blood, urine, semen, tissue, swabs (nasal, buccal, ocular, vaginal or anal).Type: ApplicationFiled: October 6, 2021Publication date: November 16, 2023Applicant: MATERIALS AND MACHINES CORPORATION OF AMERICAInventors: ABRAHAM OOMMEN, HEATHER PISCATELLI, SETH LEWIN, GOVARDHAN RATHNAIAH, ALYSSA HANGMAN
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Publication number: 20230251168Abstract: A biological sample collection system and dispensing system is described. The biological sample collection system provides for collection and processing of a biological sample (i.e. bodily fluids collected from nose, throat, or other mucosal membrane of an animal or human). The biological sample collection system includes a sample collector and a collection tube. The sample collector provides a structure for sealing the biological sample in the collection tube for further processing without opening the collection tube, and may provide a structure for collecting the biological sample. When the sample collector and collection tube are removably attached the dispensing system is formed. The dispensing system provides for further processing of the biological sample without opening the collection tube (i.e. without un-securing or removing the plug from the collection tube). The dispensing system further provides dispensing of the processed biological sample without opening the collection tube).Type: ApplicationFiled: February 8, 2022Publication date: August 10, 2023Applicant: MATERIALS AND MACHINES CORPORATION OF AMERICAInventors: Abraham Oommen, Trevor Craig, Matthew Greenleaf, Yashitola Wamboldt
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Patent number: 11667908Abstract: A portable nucleic acid extraction kit includes a portable nucleic acid extraction apparatus, at least one lysis buffer, at least one binding buffer, at least one washing buffer, at least one elution buffer, and at least three kit sample tubes. The portable nucleic acid extraction apparatus includes a handle, a rod, a tip, and may include a nucleic acid binding medium. The method of using the portable nucleic acid extraction apparatus includes, treating a biological sample having a nucleic acid, binding the nucleic acid in the treated biological sample to the tip of the portable nucleic acid extraction apparatus, incubating the tip of the portable nucleic acid extraction apparatus bound with the nucleic acid, washing the tip of the portable nucleic acid apparatus bound with the nucleic acid, eluting the bound nucleic acid, and analyzing the eluted nucleic acid.Type: GrantFiled: August 10, 2016Date of Patent: June 6, 2023Inventors: Abraham Oommen, Andrew Rush, Heather Piscatelli, Seth Lewin, Brandon Hatch
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Patent number: 10927402Abstract: A capsule to store and deliver lyophilized reagents is described. The lyophilized reagent capsule is configured to store a lyophilized reagent for at least five days, and is further configured to deliver a lyophilized reagent to a biological sample. The capsule includes a top, a bottom, and a lyophilized reagent. A method for delivering the lyophilized reagent via the capsule and without the use of pipettes to deliver the lyophilized reagents is described. The capsule may be part of a lyophilized reagent capsule kit.Type: GrantFiled: April 10, 2018Date of Patent: February 23, 2021Assignee: STEM Arts Projects, LLCInventors: Abraham Oommen, Heather Piscatelli, Molly Manning, Alyssa Hangman
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Publication number: 20200199661Abstract: Reaction condition compositions for detecting a genomic variation from a small sample amount from 5 nano grams (ng) to 1 microgram (ug) includes DNA ligase, DNA polymerase, at least one COP, a DNA polymerase buffer, NAD+, at least two primers, and deoxynucleotide triphosphates (dNTPs). Detection of the genomic variation utilizes COPs with increased ligation efficiency and RCA with fluorescence detection due to simultaneous ligation of COPs to CPs and replication of the genomic variation. The reaction condition composition eliminates the need to perform background reduction of un-hybridized or un-ligated COPs.Type: ApplicationFiled: January 11, 2019Publication date: June 25, 2020Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Heather Piscatelli, Alyssa Hangman
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Publication number: 20190309344Abstract: A capsule to store and deliver lyophilized reagents is described. The lyophilized reagent capsule is configured to store a lyophilized reagent for at least five days, and is further configured to deliver a lyophilized reagent to a biological sample. The capsule includes a top, a bottom, and a lyophilized reagent. A method for delivering the lyophilized reagent via the capsule and without the use of pipettes to deliver the lyophilized reagents is described. The capsule may be part of a lyophilized reagent capsule kit.Type: ApplicationFiled: April 10, 2018Publication date: October 10, 2019Applicant: Stem Arts Projects, LLCInventors: Abraham Oommen, Heather Piscatelli, Molly Manning, Alyssa Hangman
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Patent number: 9957500Abstract: A continuous flow nucleic acid extraction apparatus comprising a piston column apparatus for the extraction of nucleic acids from a nucleic acid sample. The disclosure also includes a method of using the continuous flow nucleic acid extraction apparatus.Type: GrantFiled: February 26, 2015Date of Patent: May 1, 2018Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch
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Publication number: 20180105809Abstract: A portable nucleic acid extraction kit includes a portable nucleic acid extraction apparatus, at least one lysis buffer, at least one binding buffer, at least one washing buffer, at least one elution buffer, and at least three kit sample tubes. The portable nucleic acid extraction apparatus includes a handle, a rod, a tip, and may include a nucleic acid binding medium. The method of using the portable nucleic acid extraction apparatus includes, treating a biological sample having a nucleic acid, binding the nucleic acid in the treated biological sample to the tip of the portable nucleic acid extraction apparatus, incubating the tip of the portable nucleic acid extraction apparatus bound with the nucleic acid, washing the tip of the portable nucleic acid apparatus bound with the nucleic acid, eluting the bound nucleic acid, and analyzing the eluted nucleic acid.Type: ApplicationFiled: August 10, 2016Publication date: April 19, 2018Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Andrew Rush, Heather Piscatelli, Seth Lewin, Brandon Hatch
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Patent number: 9810631Abstract: A wavelength scanning apparatus that detects at least four different fluorescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired fluorescent emission wavelengths, and at least four photodetectors to detect light of the desired fluorescent emission wavelengths.Type: GrantFiled: November 1, 2016Date of Patent: November 7, 2017Assignee: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20170115222Abstract: A wavelength scanning apparatus that detects at least four different fluorescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired fluorescent emission wavelengths, and at least four photodetectors to detect light of the desired fluorescent emission wavelengths.Type: ApplicationFiled: November 1, 2016Publication date: April 27, 2017Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Patent number: 9568429Abstract: A wavelength scanning apparatus that detects at least four different florescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired florescent emission wavelengths, and at least four photodetectors to detect light of the desired florescent emission wavelengths.Type: GrantFiled: July 25, 2015Date of Patent: February 14, 2017Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20170023479Abstract: A wavelength scanning apparatus that detects at least four different florescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired florescent emission wavelengths, and at least four photodetectors to detect light of the desired florescent emission wavelengths.Type: ApplicationFiled: July 25, 2015Publication date: January 26, 2017Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20160251647Abstract: A continuous flow nucleic acid extraction apparatus comprising a piston column apparatus for the extraction of nucleic acids from a nucleic acid sample. The disclosure also includes a method of using the continuous flow nucleic acid extraction apparatus.Type: ApplicationFiled: February 26, 2015Publication date: September 1, 2016Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch
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Publication number: 20160214106Abstract: A capillary diagnostic device comprising a cylindrical tube with one or more rings having one or more probes, the one or more rings disposed on the interior surface of the cylindrical tube. The invention also includes a method of making the capillary diagnostic device and method of use thereof for diagnostic testing.Type: ApplicationFiled: January 27, 2015Publication date: July 28, 2016Applicant: Materials and Machines Corporation of AmericaInventors: Abraham Oommen, Matthew Greenleaf
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Patent number: 8622215Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.Type: GrantFiled: May 6, 2011Date of Patent: January 7, 2014Assignee: Neogen CorporationInventor: Abraham Oommen
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Publication number: 20110265582Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.Type: ApplicationFiled: May 6, 2011Publication date: November 3, 2011Inventor: Abraham Oommen
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Patent number: 7959000Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.Type: GrantFiled: March 25, 2008Date of Patent: June 14, 2011Assignee: Neogen CorporationInventor: Abraham Oommen
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Publication number: 20090078064Abstract: A differential mobility analyzer that is capable of analyzing more than one sample simultaneously, comprising an aerosol generator, a particle classifier and/or a particle counter is disclosed.Type: ApplicationFiled: August 6, 2008Publication date: March 26, 2009Inventor: Abraham Oommen
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Patent number: 7470399Abstract: The present invention relates to a novel device for the collection, storage, shipping and retrieval of hair follicles from animals for the purpose of isolating DNA or other genetic material from the follicles for analysis. The device has outer flaps for the protection as well as identification of the samples and an inner part where samples are placed. The inner device has thicker base and a clear plastic cover, the easy peel back of which is facilitated by a) low tack adhesives that hold the two together and b) a touch cut on one end, through the base sheet which creates a grip. This makes the device convenient and easy to use, and yet a robust collection device for hair follicles from animals in a farm or real-life situation. Hair follicles can be punched out through the inner device for direct DNA isolation and analysis.Type: GrantFiled: May 29, 2004Date of Patent: December 30, 2008Inventor: Abraham Oommen
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Patent number: D786707Type: GrantFiled: January 19, 2016Date of Patent: May 16, 2017Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf