Patents by Inventor Ad Vermaire

Ad Vermaire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for reducing scar formation in wound healing
    Patent number: 8377881
    Abstract: The invention pertains to a method of reducing scar formation during wound healing by administering a phosphatidylserine-binding compound, in particular an annexin, to a subject in need thereof. The healing wound may be a skin damage, but it may also be a myocardium e.g. which is at risk of suffering or is recovering from a heart failure.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: February 19, 2013
    Assignee: MosaMedix B. V.
    Inventors: Peter Jozef Jacobus Moonen, Christiaan Peter Maria Reutelingsperger, Ad Vermaire
  • Annexin derivatives suitable for pretargeting in therapy and diagnosis
    Patent number: 8067357
    Abstract: The present invention provides methods and compositions for the treatment and diagnosis of diseases such as neoplastic diseases, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, and inflammatory diseases. The methods are based on the concept of pretargeting and include the administration of complexes comprising a recognizable compound A coupled to annexins, and the administration of complexes comprising of pharmaceutical or diagnostic compounds coupled to a compound B recognizing and binding to compound A to subjects. The compositions include annexins, annexin variants, that are not internalized by the target cells, derivatives thereof, and complexes thereof.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: November 29, 2011
    Assignee: Mosamedix B.V.
    Inventors: Christiaan Peter Maria Reutelingsperger, Peter Moonen, Ad Vermaire
  • COMPOSITIONS AND METHODS FOR REDUCING SCAR FORMATION IN WOUND HEALING
    Publication number: 20110091527
    Abstract: The invention pertains to a method of reducing scar formation during wound healing by administering a phosphatidylserine-binding compound, in particular an annexin, to a subject in need thereof. The healing wound may be a skin damage, but it may also be a myocardium e.g. which is at risk of suffering or is recovering from a heart failure.
    Type: Application
    Filed: April 1, 2009
    Publication date: April 21, 2011
    Applicant: MOSAMEDIX B.V.
    Inventors: Peter Jozef Jacobus Moonen, Christiaan Peter Maria Reutelingsperger, Ad Vermaire
  • ANNEXIN DERIVATIVES SUITABLE FOR PRETARGETING IN THERAPY AND DIAGNOSIS
    Publication number: 20090155170
    Abstract: The present invention provides methods and compositions for the treatment and diagnosis of diseases such as neoplastic diseases, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, and inflammatory diseases. The methods are based on the concept of pretargeting and include the administration of complexes comprising a recognizable compound A coupled to annexins, and the administration of complexes comprising of pharmaceutical or diagnostic compounds coupled to a compound B recognizing and binding to compound A to subjects. The compositions include annexins, annexin variants, that are not internalized by the target cells, derivatives thereof, and complexes thereof.
    Type: Application
    Filed: December 12, 2006
    Publication date: June 18, 2009
    Inventors: Christiaan Peter Maria Reutelingsperger, Peter Moonen, Ad Vermaire