Abstract: The inventive compounds are small molecule therapeutics that are potent inhibitors of USP7 activity. The invention also provides pharmaceutical compositions comprising the compounds, and methods for using the compounds for treating or preventing a disease, disorder, or condition associated with USP7 activity.

Abstract: The system includes a network that allows a user (an uploader), who has made a compilation playable as a video or audio or both, to visit a website and make arrangements for his or her compilation to be broadcast on one or more TV channels in various locations around the world. The uploader who has created a video, for example, will visit the website and upload his or her creation to the website. After uploading, the website will present the uploader with options as to where, on what type of outlet (media devices, terrestrial TV, video on demand, satellite TV, cable TV, Internet, mobile phone or other outlet) and when (or in what time window) his or her creation will be played. The website, optionally, may charge user or not charge the user a fee. Whether or not a fee is paid, the video may be edited in order to make it comply with broadcast safety standards and/or for compliance with rules governing the outlet over which the video will be played.