Patents by Inventor Addison V. Wright

Addison V. Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterodimeric Cas9 and methods of use thereof
    Patent number: 11208638
    Abstract: The present disclosure provides a Cas9 heterodimer, as well as nucleic acids encoding the Cas9 heterodimer, and host cells comprising the nucleic acids. The present disclosure provides a system that includes a Cas9 heterodimer of the present disclosure and at least one of: a Cas9 guide RNA, and a dimerizing agent. A Cas9 heterodimer of the present disclosure is useful in a wide variety of applications, which are also provided.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: December 28, 2021
    Assignee: The Regents of the University of California
    Inventors: Samuel H. Sternberg, Jennifer A. Doudna, Addison V. Wright
  • HETERODIMERIC CAS9 AND METHODS OF USE THEREOF
    Publication number: 20180002682
    Abstract: The present disclosure provides a Cas9 heterodimer, as well as nucleic acids encoding the Cas9 heterodimer, and host cells comprising the nucleic acids. The present disclosure provides a system that includes a Cas9 heterodimer of the present disclosure and at least one of: a Cas9 guide RNA, and a dimerizing agent. A Cas9 heterodimer of the present disclosure is useful in a wide variety of applications, which are also provided.
    Type: Application
    Filed: January 7, 2016
    Publication date: January 4, 2018
    Inventors: Samuel H. Sternberg, Jennifer A. Doudna, Addison V. Wright